OHSU Knight Cancer Institute Research Groups:OCI Cancer Journal Club

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|2/28/2013
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|2/4/2014
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|Tim Butler
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|tumor heterogeneity, focusing mostly on a recent science paper (Kreso 2013) which shows serially passages clones responding differently to chemotherapy
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|[http://openwetware.org/images/0/09/Science-2013-Kreso-543-8.pdf Kreso 2013][http://openwetware.org/images/2/25/Gerlinger_2012%2C_Intratumor_Heterogeneity_multiregion_sequencing.pdf Gerlinger 2012]
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|3/7/2013
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|2/11/2014
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|Toni West
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|Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
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|[http://openwetware.org/images/c/c3/Schwitalla_S_et_al_Cell_152%2C_25-38_%282013%29.pdf Schwitalla S et al Cell 152, 25-38 (2013)]
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|3/14/2013
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|2/18/2014
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|Jared Fischer
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|Intestinal label-retaining cells are secretory precursors expressing Lgr5
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|[http://openwetware.org/images/0/09/Nature11965%281%29.pdf]
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|3/21/2013
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|2/25/2014
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|Mushui Dai
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|Splicing-Factor Oncoprotein SRSF1 Stabilizes p53 via RPL5 and Induces Cellular Senescence.
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|[http://openwetware.org/images/5/57/2013_SRSF1_L5_p53_MC.pdf]
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|4/4/2013
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|3/4/2014
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|Nathalie Javidi-Sharifi
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|Tumor Stem Cells Generate Vasculature
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|[http://openwetware.org/images/2/25/Gsc_vasculature_hutchinson_comment_nature_2011.pdf] [http://openwetware.org/images/1/17/Gsc_pericytes_cheng_cell_2013_incl_supp.pdf]
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|4/11/2013
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|3/11/2014
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|Amy Farrell
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|Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer
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|[http://www.sciencedirect.com/science/article/pii/S1535610813000433 Stefan Eser, et al]
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|4/18/2013
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|3/18/2014
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|Trevor Levin
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|DNA damage foci formation around double strand breaks and regulation of NHEJ and HR repair mechanisms
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|[http://openwetware.org/images/5/59/Zimmermann2013_53BP1_Rif1_DSBRepair.pdf Zimmerman][http://openwetware.org/images/b/ba/Virgilio2013_Rif1_DNA_Breaks_IG_Switching.pdf Virgilio][http://openwetware.org/images/7/72/Kukas2013_Rif1_Perspective.pdf Kukas]
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|4/25/2013
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|3/25/2014
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|Kevin Watanabe-Smith
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|"Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models"
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|[http://openwetware.org/images/5/56/Corcoran_2013_Synthetic_Lethality_in_KRAS_mutant_cancer.pdf] [http://openwetware.org/images/6/68/Supplemental_-_Corcoran_2013.pdf]
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|5/2/2013
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|4/1/2014
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|Stacey Lin
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|Hijacking the Neuronal NMDAR Signaling Circuit to Promote Tumor Growth and Invasion
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|[http://openwetware.org/images/a/ac/Li_and_Hanahan.pdf]
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|5/9/2013
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|4/8/2014
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|Juan Liang
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|Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53
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|[http://openwetware.org/images/0/0e/2012_Cance_Cell_Inhibition_of_RNA_Polymerase_I_as_a_Therapeutic_Strategy.pdf]
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|5/16/201
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|4/15/2014
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|Xiaoxin Sun
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|Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP
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|[http://openwetware.org/images/5/5f/Cancer_journal_club_paper.pdf]
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|5/23/2013
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|4/22/2014
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|Dr. Charles Lopez
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|CANCELED DUE TO RESEARCH WEEK
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|5/30/2013
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|4/29/2013
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|Mahnaz Janghorban
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|Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer
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|[http://openwetware.org/images/b/b2/Loss_of_FBP1_by_Snail-Mediated_Repression_Provides_Metabolic_Advantages_in_Basal-like_Breast_Cancer.pdf Dong et al]
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|6/6/2013
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|5/6/2014
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|Marcus Calkins
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|The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation
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|[http://openwetware.org/images/5/5c/EEF2_kinase_confers_resistance_to_ND.pdf]
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|5/13/2014
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|5/20/2014
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|5/27/2014
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|6/3/2014
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|6/10/2014
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Revision as of 19:29, 6 September 2013

Equipped with his five senses, man explores the universe around him and calls the adventure Science.  ~Edwin Powell Hubble, The Nature of Science, 1954

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Contents

Objectives of the OHSU Cancer Biology Journal Club

Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles, emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:

  • Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
  • Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics

KCI CJC Information

Want to join us? All are invited!

  • To get on the listserve:
go to the following web site:
http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio
follow instructions for subscribing
  • To send out your paper
Send an e-mail to 'oncobioATohsu.edu' with your paper attached
  • When and where we meet
MacHall 2136
Thursdays noon-1 PM
Lunch provided by KCI
  • Organizer contact information:
Rosie Sears-searsr@ohsu.edu
Charlie Lopez- lopezc@ohsu.edu

Member Labs and Affiliations

Lopez Lab Hem Onc

Sears Lab

Hoatlin Lab

Thayer Lab

Wong Lab

Lloyd Lab CROET

McCullough Lab CROET

Schedule

  • Scheduling In Progress
Date Presenters Topic Links & Comments
10/1/2013 Organization
10/8/2013
10/15/2013
10/22/2013
10/29/2013
11/5/2013
11/12/2013
11/19/2013
11/26/2013
12/3/2013
12/10/2013
12/17/2013
12/24/2013 Canceled
12/31/2013
1/7/2014
1/14/2014
1/21/2014
1/28/2014
2/4/2014
2/11/2014
2/18/2014
2/25/2014
3/4/2014
3/11/2014
3/18/2014
3/25/2014
4/1/2014
4/8/2014
4/15/2014
4/22/2014
4/29/2013
5/6/2014
5/13/2014
5/20/2014
5/27/2014
6/3/2014
6/10/2014
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