OHSU Knight Cancer Institute Research Groups:OCI Cancer Journal Club: Difference between revisions
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| Line 57: | Line 57: | ||
|Amy Farrell | |Amy Farrell | ||
|Ubiquitylation of the amino terminus of Myc by SCF<sup>β-TrCp</sup> antagonizes SCF<sup>Fbw7</sup>-mediated turnover | |Ubiquitylation of the amino terminus of Myc by SCF<sup>β-TrCp</sup> antagonizes SCF<sup>Fbw7</sup>-mediated turnover | ||
| | | | ||
|-- | |-- | ||
|10/14/2010 | |10/14/2010 | ||
| Line 64: | Line 64: | ||
Stress-Promoted Transcription via | Stress-Promoted Transcription via | ||
Histone H2B Phosphorylation | Histone H2B Phosphorylation | ||
| | | | ||
|-- | |-- | ||
|10/21/2010 | |10/21/2010 | ||
|Anupriya Agarwal | |Anupriya Agarwal | ||
| Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. | | Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. | ||
| | | | ||
|-- | |-- | ||
|10/28/2010 | |10/28/2010 | ||
|Deanne Tibbitts | |Deanne Tibbitts | ||
| Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate | | Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate | ||
| | | | ||
|-- | |-- | ||
|11/4/2010 | |11/4/2010 | ||
|Mushui Dai | |Mushui Dai | ||
|An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction | |An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction | ||
| | | | ||
|-- | |-- | ||
|11/11/2010 | |11/11/2010 | ||
|Katy Van Hook | |Katy Van Hook | ||
|Bacteri-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity | |Bacteri-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity | ||
| | | | ||
|-- | |-- | ||
|11/18/2010 | |11/18/2010 | ||
|Aaron Wortham | |Aaron Wortham | ||
|Cytohesins Are Cytoplasmic ErbB Receptor Activators | |Cytohesins Are Cytoplasmic ErbB Receptor Activators | ||
| | | | ||
|-- | |-- | ||
|11/25/2010 | |11/25/2010 | ||
| Line 99: | Line 99: | ||
|Xiaoli Zhang | |Xiaoli Zhang | ||
|A Stapled p53 Helix overcomes HDMX-mediated suppression of p53 | |A Stapled p53 Helix overcomes HDMX-mediated suppression of p53 | ||
| | | | ||
|-- | |-- | ||
|12/9/2010 | |12/9/2010 | ||
| Line 109: | Line 109: | ||
|Beibei Dong | |Beibei Dong | ||
|Copper Transporter and Cisplatin | |Copper Transporter and Cisplatin | ||
| | | | ||
|-- | |-- | ||
|1/6/2011 | |1/6/2011 | ||
|Alain Silk | |Alain Silk | ||
|Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization | |Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization | ||
| | | | ||
|-- | |-- | ||
|1/13/2011 | |1/13/2011 | ||
| Line 124: | Line 124: | ||
|Eric Stoffregen | |Eric Stoffregen | ||
|Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncohenic Transformation | |Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncohenic Transformation | ||
| | | | ||
|-- | |-- | ||
|1/27/2011 | |1/27/2011 | ||
|Mahnaz Janghorban | |Mahnaz Janghorban | ||
|B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer | |B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer | ||
| | | | ||
|-- | |-- | ||
|2/3/2011 | |2/3/2011 | ||
|Katannya Kapeli | |Katannya Kapeli | ||
|The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-b Pathway in Neuroblastoma | |The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-b Pathway in Neuroblastoma | ||
| | | | ||
|-- | |-- | ||
|2/10/2011 | |2/10/2011 | ||
| Line 145: | Line 144: | ||
|Jason Link | |Jason Link | ||
|Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation | |Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation | ||
| | | | ||
|-- | |-- | ||
|2/24/2011 | |2/24/2011 | ||
|Rosie Sears | |Rosie Sears | ||
|The blind spot of p53 <br> Stage-specific sensitivity to p53 restoration during lung cancer progression <br> Selective activation of p53-mediated tumour suppression in high-grade tumours | |The blind spot of p53 <br> Stage-specific sensitivity to p53 restoration during lung cancer progression <br> Selective activation of p53-mediated tumour suppression in high-grade tumours | ||
| | | | ||
|-- | |-- | ||
|3/3/2011 | |3/3/2011 | ||
|Amy Skinner | |Amy Skinner | ||
|Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth | |Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth | ||
| | | | ||
|-- | |-- | ||
|3/10/2011 | |3/10/2011 | ||
|Tiffany DeVine | |Tiffany DeVine | ||
|Activation of mTORC2 by Association with the Ribosome | |Activation of mTORC2 by Association with the Ribosome | ||
| | | | ||
|-- | |-- | ||
|3/17/2011 | |3/17/2011 | ||
|Aaron Jacobs | |Aaron Jacobs | ||
|Identification of Aneuploidy-Selective Antiproliferation Compounds | |Identification of Aneuploidy-Selective Antiproliferation Compounds | ||
| | | | ||
|-- | |-- | ||
|3/31/2011 | |3/31/2011 | ||
|Harini Sampath | |Harini Sampath | ||
|Dietary and genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression | |Dietary and genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression | ||
| | | | ||
|-- | |-- | ||
|4/7/2011 | |4/7/2011 | ||
|Yun Xin Lim | |Yun Xin Lim | ||
|Sensitivity to Atitubulin Chemotherapeutics is Regulated by MC:1 and FBW7 | |Sensitivity to Atitubulin Chemotherapeutics is Regulated by MC:1 and FBW7 | ||
| | | | ||
|-- | |-- | ||
|4/14/2011 | |4/14/2011 | ||
| Line 188: | Line 185: | ||
|Liangqi Xie | |Liangqi Xie | ||
|Rapid Scalable RNA1 in Mice | |Rapid Scalable RNA1 in Mice | ||
| | | | ||
|-- | |-- | ||
|4/28/2011 | |4/28/2011 | ||
|Kinrin Yamanaka | |Kinrin Yamanaka | ||
|DNA damage-mediated induction of chemoresistant niche | |DNA damage-mediated induction of chemoresistant niche | ||
| | | | ||
|-- | |-- | ||
|5/5/2011 | |5/5/2011 | ||
|Kishore Challagundla | |Kishore Challagundla | ||
|LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans | |LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans | ||
| | | | ||
|-- | |-- | ||
|5/12/2011 | |5/12/2011 | ||
| Line 208: | Line 205: | ||
|Jeff Wu | |Jeff Wu | ||
|Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism | |Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism | ||
| | | | ||
|-- | |-- | ||
|5/26/2011 | |5/26/2011 | ||
|Vince Bicocca | |Vince Bicocca | ||
|AKT Inhibition Relieves Feedback Suppression of Receptor Tyrosine Kinase Expression and Activity | |AKT Inhibition Relieves Feedback Suppression of Receptor Tyrosine Kinase Expression and Activity | ||
| | | | ||
|-- | |-- | ||
|6/2/2010 | |6/2/2010 | ||
|Xiangshu Xiao | |Xiangshu Xiao | ||
|Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer | |Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer | ||
| | | | ||
|-- | |-- | ||
|6/9/2011 | |6/9/2011 | ||
|Arun Krishnamoorthy | |Arun Krishnamoorthy | ||
|Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways | |Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways | ||
| | | | ||
|} | |} | ||
</div> | </div> | ||
Revision as of 08:15, 21 June 2011
Home Faculty Graduate Program Postdocs OHSU Knight Core Facilities
Programs
Res Group Meetings
Cancer Journal Club
Cell/CANB 616
Gen. Inst/R3 Club
CANB 610
Objectives of the OHSU Cancer Biology Journal Club
Cross-departmental workshop composed of students, postdocs, and faculty with shared interest in basic principles and emerging discoveries in Cancer Biology. The goals of the meetings and this wiki:
- Establish a challenging and interactive cross-departmental focus group that will advance understanding of our individual projects and encourage collaborations.
- Provide students and postdocs with training and interactions with faculty interested in Cancer Biology and emerging therapeutics
OCI CJC Activities
Want to join us? All are invited!
- To get on the listserve:
- Email: majordomoATohsu.edu (must be sent as a plain text email)
- subject: subscribe oncobio
- text box: subscribe oncobio
- When and where we meet
- MacHall 2136
- Thursdays noon-1 PM
- Lunch provided by OCI
- Organizer contact information: searsrATohsu.edu, lopezcATohsu.edu
Member Labs and Affiliations
Lopez Lab Hem Onc
Lloyd Lab CROET
McCullough Lab CROET
Schedule
- Scheduling In Progress
| Date | Presenters | Topic | Links & Comments |
| 9/30/2010 | Rosie Sears | Organization | |
| 10/7/2010 | Amy Farrell | Ubiquitylation of the amino terminus of Myc by SCFβ-TrCp antagonizes SCFFbw7-mediated turnover | |
| 10/14/2010 | David Qian | Signaling Kinase AMPK Activates
Stress-Promoted Transcription via Histone H2B Phosphorylation |
|
| 10/21/2010 | Anupriya Agarwal | Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. | |
| 10/28/2010 | Deanne Tibbitts | Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate | |
| 11/4/2010 | Mushui Dai | An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction | |
| 11/11/2010 | Katy Van Hook | Bacteri-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity | |
| 11/18/2010 | Aaron Wortham | Cytohesins Are Cytoplasmic ErbB Receptor Activators | |
| 11/25/2010 | xxxxxxxxxx | THANKSGIVING, NO JOURNAL CLUB | xxxxxxxxxx |
| 12/2/2010 | Xiaoli Zhang | A Stapled p53 Helix overcomes HDMX-mediated suppression of p53 | |
| 12/9/2010 | CANCELLED | ||
| 12/16/2010 | Beibei Dong | Copper Transporter and Cisplatin | |
| 1/6/2011 | Alain Silk | Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization | |
| 1/13/2011 | Xiao-Xin Sun | Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer; ( Schramek D et al, Nature. 2010 Nov 4;468(7320):98-102) | |
| 1/20/2011 | Eric Stoffregen | Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncohenic Transformation | |
| 1/27/2011 | Mahnaz Janghorban | B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer | |
| 2/3/2011 | Katannya Kapeli | The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-b Pathway in Neuroblastoma | |
| 2/10/2011 | Jared Fischer | Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells | [1] |
| 2/17/2011 | Jason Link | Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation | |
| 2/24/2011 | Rosie Sears | The blind spot of p53 Stage-specific sensitivity to p53 restoration during lung cancer progression Selective activation of p53-mediated tumour suppression in high-grade tumours |
|
| 3/3/2011 | Amy Skinner | Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth | |
| 3/10/2011 | Tiffany DeVine | Activation of mTORC2 by Association with the Ribosome | |
| 3/17/2011 | Aaron Jacobs | Identification of Aneuploidy-Selective Antiproliferation Compounds | |
| 3/31/2011 | Harini Sampath | Dietary and genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression | |
| 4/7/2011 | Yun Xin Lim | Sensitivity to Atitubulin Chemotherapeutics is Regulated by MC:1 and FBW7 | |
| 4/14/2011 | Gregory Gores, M.D.
Division of Gastroenterology and Hepatology Mayo Clinic, Rochester, MN |
TRAIL triggers the lysosomal pathway of apoptosis | Vollum M1441 |
| 4/21/2011 | Liangqi Xie | Rapid Scalable RNA1 in Mice | |
| 4/28/2011 | Kinrin Yamanaka | DNA damage-mediated induction of chemoresistant niche | |
| 5/5/2011 | Kishore Challagundla | LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans | |
| 5/12/2011 | *****STUDENT RESEARCH FORUM***** | ||
| 5/19/2011 | Jeff Wu | Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism | |
| 5/26/2011 | Vince Bicocca | AKT Inhibition Relieves Feedback Suppression of Receptor Tyrosine Kinase Expression and Activity | |
| 6/2/2010 | Xiangshu Xiao | Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer | |
| 6/9/2011 | Arun Krishnamoorthy | Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways |
