Nowlan:Opportunities: Difference between revisions
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Opportunities are available in the Developmental Biomechanics group for excellent UK/EU PhD applicants to the Bioengineering Department Centre for Doctoral Training (CDT). The two projects advertised are described below. For further details please contact [[Nowlan:Contact|Dr Nowlan]] by email. | Opportunities are available in the Developmental Biomechanics group for excellent UK/EU PhD applicants to the Bioengineering Department Centre for Doctoral Training (CDT). The two projects advertised are described below. For further details please contact [[Nowlan:Contact|Dr Nowlan]] by email. | ||
Recapitulating skeletogenesis in vitro: biomechanics and mechanobiology of cartilage and bone development | |||
'''Recapitulating skeletogenesis in vitro: biomechanics and mechanobiology of cartilage and bone development''' | |||
Research from our group has shown that mechanical stimulation due to fetal movements (in vivo) or due to applied mechanical forces (in vitro) leads to measureable changes in growth and shape effects in the developing skeleton. This project will use a bioreactor system to culture developing chick and mouse limb explants in order to quantify the relationship between movements and developmental change, and to explore the cell and organelle level changes leading to the observed changes. The work will be highly relevant to tissue engineering of cartilage and bone, as we will be aiming to use mechanical forces to more closely recapitulate developmental processes leading to functional skeletal tissues. This project would be suitable for candidates from either biology or engineering backgrounds. | Research from our group has shown that mechanical stimulation due to fetal movements (in vivo) or due to applied mechanical forces (in vitro) leads to measureable changes in growth and shape effects in the developing skeleton. This project will use a bioreactor system to culture developing chick and mouse limb explants in order to quantify the relationship between movements and developmental change, and to explore the cell and organelle level changes leading to the observed changes. The work will be highly relevant to tissue engineering of cartilage and bone, as we will be aiming to use mechanical forces to more closely recapitulate developmental processes leading to functional skeletal tissues. This project would be suitable for candidates from either biology or engineering backgrounds. | ||
Revision as of 02:44, 27 November 2015
2016 PhD Studentships for UK/EU ApplicantsOpportunities are available in the Developmental Biomechanics group for excellent UK/EU PhD applicants to the Bioengineering Department Centre for Doctoral Training (CDT). The two projects advertised are described below. For further details please contact Dr Nowlan by email.
Research from our group has shown that mechanical stimulation due to fetal movements (in vivo) or due to applied mechanical forces (in vitro) leads to measureable changes in growth and shape effects in the developing skeleton. This project will use a bioreactor system to culture developing chick and mouse limb explants in order to quantify the relationship between movements and developmental change, and to explore the cell and organelle level changes leading to the observed changes. The work will be highly relevant to tissue engineering of cartilage and bone, as we will be aiming to use mechanical forces to more closely recapitulate developmental processes leading to functional skeletal tissues. This project would be suitable for candidates from either biology or engineering backgrounds.
MRes Opportunities for 2016/17Opportunities are available in the Developmental Biomechanics group for enthusiastic MRes students. The research focus of the group is the importance of fetal movements for skeletal development. When a baby doesn’t move enough in the womb, their bones and joints may not form normally, and our research aims to find out why and how this can occur. Both experimental and computational projects are available, and researchers from either a biology (e.g., developmental biology, physiology, genetics) or engineering background are welcome- we are an interdisciplinary group! If you are interested in pursuing an MRes project in our group then please email Dr Nowlan to arrange a chat and include in your email (a) your CV and (b) a brief description of what type of project you are interested in and why. Please note that applicants must arrange their own funding sources. Possible project ideas:
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