Neomycin
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Experimental
target organism: bacteria, mammalian cells stock solution: 10mg/ml in water working solution: 10-50µg/ml (stable at RT for 5days)
Description
mode of action: binds to ribosomal components and inhibits protein synthesis. mode of resistance: neo/kan resistance gene is an aminoglycoside 3'-phosphotransferase, which inactivates G418, neomycin, and kanamycin by phosphorylation.