Neomycin

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Contents

Experimental

Target organism

bacteria, mammalian cells

Stock solution

10mg/ml in water

Working solution

10-50µg/ml

Description

Mode of action

Binds to ribosomal components and inhibits protein synthesis.

Mode of resistance

neo/kan resistance gene is an aminoglycoside 3'-phosphotransferase, which inactivates G418, neomycin, and kanamycin by phosphorylation.

Related antibiotics

kanamycin, G418

External links

  • list of cell culture reagents by Krackeler [1]
  • list of cell culture reagents by USB [2]
  • forum thread on difference between neomycin & G418 [3]
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