Nachury

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The Nachury Lab is part of the department of [http://mcp.stanford.edu/ Molecular and Cellular Physiology] at [http://med.stanford.edu/ Stanford University School of Medicine].<br>Our lab is interested in using a combination of interdisciplinary approaches encompassing protein biochemistry, cell biology, in vitro assays, digital microscopy and mammalian cell engineering to study the molecular etiology of complex hereditary human diseases.<br>
The Nachury Lab is part of the department of [http://mcp.stanford.edu/ Molecular and Cellular Physiology] at [http://med.stanford.edu/ Stanford University School of Medicine].<br>Our lab is interested in using a combination of interdisciplinary approaches encompassing protein biochemistry, cell biology, in vitro assays, digital microscopy and mammalian cell engineering to study the molecular etiology of complex hereditary human diseases.<br>
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A major focus of the lab is the study of the primary cilium, a once-obscure cellular organelle that has been "re-discovered" for its role in a number of signaling pathways (Hedgehog, Planar Cell Polarity,..). Most fascinatingly, defects in cilium biogenesis lead to a variety of symptoms such as retinal degeneration, kidney cysts, obesity, polydactyly, randomization of left-right asymmetry, etc.  
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A major focus of the lab is the study of the primary cilium, a once-obscure cellular organelle that has been "re-discovered" for its role in a number of signaling pathways (Hedgehog, Planar Cell Polarity, PDGF,..). Most fascinatingly, defects in cilium biogenesis lead to a variety of symptoms such as retinal degeneration, kidney cysts, obesity, polydactyly, randomization of left-right asymmetry, etc.  
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Revision as of 23:07, 9 January 2008

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The Nachury Lab is part of the department of Molecular and Cellular Physiology at Stanford University School of Medicine.
Our lab is interested in using a combination of interdisciplinary approaches encompassing protein biochemistry, cell biology, in vitro assays, digital microscopy and mammalian cell engineering to study the molecular etiology of complex hereditary human diseases.
A major focus of the lab is the study of the primary cilium, a once-obscure cellular organelle that has been "re-discovered" for its role in a number of signaling pathways (Hedgehog, Planar Cell Polarity, PDGF,..). Most fascinatingly, defects in cilium biogenesis lead to a variety of symptoms such as retinal degeneration, kidney cysts, obesity, polydactyly, randomization of left-right asymmetry, etc.

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