Efflux Pumps provide a direct mechanism to alleviate product toxicity (Image prepared by Everett Kaplan (JBEI))
Welcome to the Mukhopadhyay Group page!!
We are an interdisciplinary team at the Berkeley Lab studying signaling and stress response in both environmental and engineered organisms. We are part of the ENIGMA project where our research includes the study of two component signaling in the model sulfate reducing bacterium Desulfovibrio vulgaris Hildenborough. As part of the Joint BioEnergy Institute we adopt targeted and systems biology approaches to elucidate causes of inhibition during fuel/ solvent production from lignocellulose using the host microbes such as Escherichia coli and Saccharomyces cerevisiae. We hope to engineer better hosts for metabolite production and develop tools that are universally useful for microbial cellular engineering. Recently we have also become interested in studying signaling and response in cyanobacteria that dominate desert soil crusts.
Left to Right: Kavya, Melissa, Nhat-Tan, Lara, Marijke, Camille, Florence, Jee-Loon, Aindrila, Eric, Heather, Zain and Amanda The whole group at the Can't Fail cafe. We have new members in the group - Amanda Reider Appel and Nhat Than Vuong!
Feb 14th 2012
Science Today, a UC Berkeley Radio channel, features comments on our study of the D. vulgaris two component system regulator network.
Nov 9th 2011
Lara and Eric's Response Regulator Map paper gets written about in Berkeley Lab's TABL site.
(Photo by Roy Kaltschmidt, Berkeley Lab)Mario (in the blue lab coat!!) features in the Berkeley Lab news letter TABL for his important contribution in developing Bisabolene production in yeast. Here is a link to Pamela and TaekSoon's Nature Communications paper
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