Matthew E. Jurek Week 12

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Matthew E. Jurek BIOL398-03/S13

Assignment Page

User Page

Analyzing and Interpreting STEM Results

  1. Why did you select this profile? In other words, why was it interesting to you?
    • I chose Profile 9 because it is down-regulated. My partner, Anthony, is focusing on a profile that is up-regulated. We thought it'd be interesting if we each explored a profile that behaved differently.
  2. How many genes belong to this profile?
    • There are 95 genes belonging to this profile.
  3. How many genes were expected to belong to this profile?
    • 23.9 genes were expected to belong to this profile.
  4. What is the p value for the enrichment of genes in this profile?
    • The p-value for this profile is 3.3X10-29.
  5. How many GO terms are associated with this profile at p < 0.05?
    • 14 GO terms are associated with this p-value.
  6. How many GO terms are associated with this profile with a corrected p value < 0.05?
    • 1 GO term is associated with this corrected p-value.
  7. Look up the definitions for each of the terms at http://geneontology.org. Write a paragraph that describes the biological interpretation of these GO terms. In other words, why does the cell react to cold shock by changing the expression of genes associated with these GO terms?
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