Matt Gethers/20.380 HIV Project/Technical Paper/IP Outline: Difference between revisions
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*If that does not work, we will offer him a 25% (?) share of our equity and a position on our scientific advisory board | *If that does not work, we will offer him a 25% (?) share of our equity and a position on our scientific advisory board | ||
*The novel part of our idea is the use of stem cells to generate erythrocyte viral traps, and we will try to patent this aspect | *The novel part of our idea is the use of stem cells to generate erythrocyte viral traps, and we will try to patent this aspect | ||
===Citations=== | |||
<biblio>King pmid=8844435 </biblio> | |||
<biblio>Schackman pmid=17063130 </biblio> | |||
<biblio>Helle pmid=17914604 </biblio> |
Revision as of 08:20, 20 April 2009
Timeline for Development & Conclusion
Company Timeline
- We will seek an initial round of funding to do initial in vitro and in vivo experiments
- After drug is approved we will begin treating first-world patients who can afford the initially expensive treatment
- Simultaneously we will begin developing the same approach to treat other viral diseases such as the various hepatitis viruses
- We will seek patients’ and possibly non-infected blood donors to consent to us storing their engineered hematopoietic stem cells for future use in creating a library of stem cells
- This will remove the necessity of drawing a patient's blood to generate patient-specific stem cells, lowering costs
- Once we show our treatment is financially feasible, we will actively seek out funding from NGOs to expand our scope and begin treatment in third-world countries
- Our reservoir of HSCs and experience in treating first-world patients will reduce the cost of treating patients in the third-world enough to provide treatment to everyone
Financial Considerations
- Figure out estimated costs to do this
Intellectual Property
- We will probably have to license the Glaser patent since it covers so much of our idea
- We will first attempt to purchase the exclusive rights to his patent for $XXX
- If that does not work, we will offer him a 25% (?) share of our equity and a position on our scientific advisory board
- The novel part of our idea is the use of stem cells to generate erythrocyte viral traps, and we will try to patent this aspect
Citations
- King KE, Ness PM, Braine HG, and Armstrong KS. Racial differences in the availability of human leukocyte antigen-matched platelets. J Clin Apher. 1996;11(2):71-7. DOI:10.1002/(SICI)1098-1101(1996)11:2<71::AID-JCA3>3.0.CO;2-7 |