MES
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2--(N-morpholino)ethanesulfonic acid, CAS 4432-31-9 | 2--(N-morpholino)ethanesulfonic acid, CAS 4432-31-9 | ||
| - | <cite>Good66 | + | <cite>Good66,Good74,Blanchard84</cite>. Stable pH vs. temperature, no primary amine groups, no metal chelation, near physiologic pH range. |
| - | * pK<sub>a</sub> at | + | * pK<sub>a</sub> at 25°C of 6.10 (5.97 at 37°C) |
* usable buffering range of 5.5 to 6.7 | * usable buffering range of 5.5 to 6.7 | ||
* molecular weight 195.24 | * molecular weight 195.24 | ||
Current revision
2--(N-morpholino)ethanesulfonic acid, CAS 4432-31-9 [1, 2, 3]. Stable pH vs. temperature, no primary amine groups, no metal chelation, near physiologic pH range.
- pKa at 25°C of 6.10 (5.97 at 37°C)
- usable buffering range of 5.5 to 6.7
- molecular weight 195.24
- ΔpKa/ΔT = -.011
Buffers are typically 1 M, prepared by neutralizing MES with sodium hydroxide.
- Good NE, Winget GD, Winter W, Connolly TN, Izawa S, and Singh RM. . pmid:5942950.
- Good NE and Izawa S. . pmid:4206745.
- Blanchard JS. . pmid:6717292.
