LiguoWang

Contact Information

• Wang Liguo Ph.D
• Mayo Clinic
• Division of Biomedical Statistics and Informatics
• 200 First Street SW Rochester MN, 55905

Education & Experience

• Postdoc Associate, 06/2008 - 06/2012 Division of Biostatistics and Informatics. Baylor College of Medicine
• Ph.D., Bioinformatics, Beijing Genomics Institute (BGI) Chinese Academy of Sciences, 2009
• M.S., Bioinformatics, Beijing Genomics Institute (BGI) Chinese Academy of Sciences, 2005
• B.S., Biotechnology, Xuzhou Normal University, Jiangsu 221116, China. 2003

Research interests

• Computational biology, Bioinformatics, Biostatistics
• High throughput sequencing based data (RNA-seq, DNA-seq, Exome-Seq, ChIP-Exo, ChIP-seq, ChIP-chip, DNA methylation, Microarray) mining and analyses.
• Clinical data analyses.

Publications

• Rijnkels M, Freeman-Zadrowski C, Hernandez J, Potluri V, Wang L, Li W, Lemay DG. Epigenetic modifications unlock the milk protein gene loci during mouse mammary gland development and differentiation. PLoS One. 2013; 8(1):e53270. Epub 2013 Jan 02. PubMed
• Wang L, Park HJ, Dasari S, Wang S, Kocher JP, Li W. CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model. Nucleic Acids Res. 2013 Jan 17. PubMed
• Wang L, Wang S, Li W. RSeQC: Quality Control of RNA-seq experiments. Bioinformatics (2012) PubMed

• Kannan K, Wang L (joint first author), et al. Recurrent chimeric RNAs enriched in human prostate cancer identified by deep sequencing. PNAS (2011) PubMed

• Daines B, Wang H, Wang L (joint first author), et al. The Drosophila melanogaster transcriptome by paired-end RNA sequencing. Genome Res (2011) PubMed

• Zhang C, Wang L (joint first author), et al. Definition of a FoxA1 Cistrome that is Crucial for G1-S Phase Cell- Cycle Transit in Castration-Resistant Prostate Cancer. Cancer Res. (2011) PubMed

• Klisch T. J., Xi Y., Flora A., Wang L, Li W, and Zoghbi H. Y. In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development. PNAS (2011) PubMed

• Chen Z, Wang L (joint first author), Wang Q, and Li W. Histone modifications and chromatin organization in prostate cancer. Epigenomics (2011) PubMed

• Lanz RB, Bulynko Y, Malovannaya A, Labhart P, Wang L, Li W, Qin J, Harper M, O'Malley BW. Global Characterization of Transcriptional Impact of the SRC-3 Coregulator. Molecular Endocrinology. Mol Endocrinol (2010) PubMed
• Wang L, Xi Y, Yu J, Dong L, Yen L, Li W. A Statistical Method for the Detection of Alternative Splicing Using RNA-Seq. PLoS ONE (2010) PubMed

• Wang L, Hao L, Li X, Hu S, Ge S & Yu J. SNP deserts of Asian cultivated rice: genomic regions under domestication. J Evolution Biol. (2009)PubMed
• Li X, Tan L, Wang L, Hu, S. & Sun, C. Isolation and characterization of conserved non-coding sequences among rice (Oryza sativa L.) paralogous regions. Mol Genet Genomics (2008) Pubmed
• Wang W, Meng B, Ge X, Song S, Yang Y, Yu X, Wang L., Hu S, Liu S, Yu J. Proteomic profiling of rice embryos from a hybrid rice cultivar and its parental lines. Proteomics (2008) PubMed

Software

• RSeQC: Quality Control of RNA-seq experiments
• CPAT: Coding Potential Assessment Tool