Lee:JC: Difference between revisions
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==Lee Lab Research Meeting== | ==Lee Lab Research Meeting== | ||
* | * 4 - 5:30 pm, every other Monday, BPC Rm 387 | ||
==Lee Lab JC== | ==Lee Lab JC== | ||
* | * 4-5:30 pm, every other Monday, BPC Rm 387 | ||
{| border="1" | {| border="1" | ||
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|width='200'|'''Presenter''' | |width='200'|'''Presenter''' | ||
|- | |- | ||
| | |4/1/13 || Youngran | ||
|- | |- | ||
| | |4/15/13 || Nilay | ||
|- | |- | ||
| | |4/29/13 || Lin | ||
|- | |- | ||
| | |5/13/13 || Nilay | ||
|- | |- | ||
|} | |} | ||
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|width='200'|'''Presenter/discussion leader''' | |width='200'|'''Presenter/discussion leader''' | ||
|- | |- | ||
| | |01/30/13 || Kim | ||
|- | |||
|02/27/13 || Ji-Eun | |||
|- | |- | ||
| | |03/27/13 || Lin | ||
|- | |- | ||
| | |04/24/13 || Zach | ||
|- | |- | ||
| | |05/29/13 || Do-Min | ||
|}<br> | |}<br> | ||
==Suggested future papers== | ==Suggested future papers== | ||
# Eloranta JJ, Hiller C, Juttner M, Kullak-Ublick GA. The SLCO1A2 Gene, Encoding the Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2), is Transactivated by the Vitamin D Receptor (VDR). Mol Pharmacol. 2012 Apr 3. [Epub ahead of print] | # Eloranta JJ, Hiller C, Juttner M, Kullak-Ublick GA. The SLCO1A2 Gene, Encoding the Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2), is Transactivated by the Vitamin D Receptor (VDR). Mol Pharmacol. 2012 Apr 3. [Epub ahead of print] | ||
# Roué G, Pérez-Galán P, Mozos A, López-Guerra M, Xargay-Torrent S, Rosich L, Saborit-Villarroya I, Normant E, Campo E, Colomer D. The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78. Blood. 2011 Jan 27;117(4):1270-9. Epub 2010 Nov 24. | # Roué G, Pérez-Galán P, Mozos A, López-Guerra M, Xargay-Torrent S, Rosich L, Saborit-Villarroya I, Normant E, Campo E, Colomer D. The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78. Blood. 2011 Jan 27;117(4):1270-9. Epub 2010 Nov 24. | ||
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==Past papers== | ==Past papers== | ||
===2013=== | |||
# Pinilla-Macua I, Casado FJ, Pastor-Anglada M. Structural determinants for rCNT2 sorting to the plasma membrane of polarized and non-polarized cells. Biochem J. 2012 Mar 15;442(3):517-25. doi: 10.1042/BJ20110605. (1/7/13 NT) | |||
# Day E, Waters B, Spiegel K, Alnadaf T, Manley PW, Buchdunger E, Walker C, Jarai G. Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib.Eur J Pharmacol. 2008 Dec 3;599(1-3):44-53 (2/4/13 YRL) | |||
# Ramachandran A, Betts G, Bhana S, Helme G, Blick C, Moller-Levet C, Saunders E, Valentine H, Pepper S, Miller CJ, Buffa F, Harris AL, West CM. An in vivo hypoxia metagene identifies the novel hypoxia inducible factor target gene SLCO1B3. Eur J Cancer. 2013 Jan 23. doi:pii: S0959-8049(12)00960-4. 10.1016/j.ejca.2012.12.003 (2/18/13, KBK) | |||
# Maldonado M, Kapphahn RJ, MR Terluk, ND Heuss, C Yuan, DS Gregerson, DA Ferrington. Immunoproteasome Deficiency Modifies the Alternative Pathway of NFκB Signaling. Plos One 2013 (3/4/13, LA) | |||
===2012=== | ===2012=== | ||
# Fang C, Dean J, Smith JW. A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. Cancer Res. 2007 Oct 1;67(19):9039-46. (pmid=17909007) (1/17/12 SH) | # Fang C, Dean J, Smith JW. A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. Cancer Res. 2007 Oct 1;67(19):9039-46. (pmid=17909007) (1/17/12 SH) | ||
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# Higashimura Y, Nakajima Y, Yamaji R, Harada N, Shibasaki F, Nakano Y, Inui H. Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells. Arch Biochem Biophys. 2011 May 1;509(1):1-8. (PMID=21338575) (7/31/12 SHH) | # Higashimura Y, Nakajima Y, Yamaji R, Harada N, Shibasaki F, Nakano Y, Inui H. Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells. Arch Biochem Biophys. 2011 May 1;509(1):1-8. (PMID=21338575) (7/31/12 SHH) | ||
# Errasti-Murugarren E, Casado FJ, Pastor-Anglada M. Different N-terminal motifs determine plasma membrane targeting of the human concentrative nucleoside transporter 3 in polarized and nonpolarized cells. Mol Pharmacol. 2010 Nov;78(5):795-803. (PMID=20643903 8/14/12 NT) | # Errasti-Murugarren E, Casado FJ, Pastor-Anglada M. Different N-terminal motifs determine plasma membrane targeting of the human concentrative nucleoside transporter 3 in polarized and nonpolarized cells. Mol Pharmacol. 2010 Nov;78(5):795-803. (PMID=20643903 8/14/12 NT) | ||
# Hammerman PS et al. Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. Cancer Discov. 2011 Jun;1(1):78-89. (PMID=22328973, 8/28/12 YRL) | |||
# Heink S, Ludwig D, Kloetzel PM, Krüger E. IFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient response. Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9241-6. (PMID: 15944226 9/10/12 KBj) | |||
# Blackburn C, Gigstad KM, Hales P, Garcia K, Jones M, Bruzzese FJ, Barrett C, Liu JX, Soucy TA, Sappal DS, Bump N, Olhava EJ, Fleming P, Dick LR, Tsu C, Sintchak MD, Blank JL. Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit. Biochem J. 2010 Sep 15;430(3):461-76. (9/24/12 JP) | |||
# Joeris T, Schmidt N, Ermert D, Krienke P, Visekruna A, Kuckelkorn U, Kaufmann SH, Steinhoff U. The proteasome system in infection: impact of β5 and LMP7 on composition, maturation and quantity of active proteasome complexes. PLoS One. 2012;7(6):e39827. (10/9/12 LA) | |||
# Tainton KM, Smyth MJ, Jackson JT, Tanner JE, Cerruti L, Jane SM, Darcy PK, Johnstone RW.Mutational analysis of P-glycoprotein: suppression of caspase activation in the absence of ATP-dependent drug efflux. Cell Death Differ. 2004 Sep;11(9):1028-37. PMID: 15131592 (10/22/12 NT) | |||
# Yang K, Kim JH, Kim HJ, Park IS, Kim IY, Yang BS. Tyrosine 740 phosphorylation of discoidin domain receptor 2 by Src stimulates intramolecular autophosphorylation and Shc signaling complex formation. J Biol Chem. 2005 Nov 25;280(47):39058-66. (11/5/12 YRL) | |||
# Mishto M, Santoro A, Bellavista E, Sessions R, Textoris-Taube K, Dal Piaz F, Carrard G, Forti K, Salvioli S, Friguet B, Kloetzel PM, Rivett AJ, Franceschi C. A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms. Biol Chem. 2006 Apr;387(4):417-29. (PMID:16606340) (11/19/12 JP) | |||
# Mizukami Y, Fujiki K, Duerr EM, Gala M, Jo WS, Zhang X, Chung DC. Hypoxic regulation of vascular endothelial growth factor through the induction of phosphatidylinositol 3-kinase/Rho/ROCK and c-Myc. J Biol Chem. 2006;281(20):13957-63. (12/3/12, KBj) | |||
# Lansdell TA, Hurchla MA, Xiang J, Hovde S, Weilbaecher KN, Henry RW, Tepe JJ. Noncompetitive Modulation of the Proteasome by Imidazoline Scaffolds Overcomes Bortezomib Resistance and Delays MM Tumor Growth in Vivo. ACS Chem Biol. 2012 Dec 11. (12/17/11, LA) | |||
===2011=== | ===2011=== | ||
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# Taub ME, Mease K, Sane RS, Watson CA, Chen L, Ellens H, Hirakawa B, Reyner EL, Jani M, Lee CA. Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells. Drug Metab Dispos. 2011 Nov;39(11):2093-102. Epub 2011 Aug 17. | # Taub ME, Mease K, Sane RS, Watson CA, Chen L, Ellens H, Hirakawa B, Reyner EL, Jani M, Lee CA. Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells. Drug Metab Dispos. 2011 Nov;39(11):2093-102. Epub 2011 Aug 17. | ||
===2010 | ===2010=== | ||
# Parlati F, Lee SJ, Aujay M, Suzuki E, Levitsky K, Lorens JB, Micklem DR, Ruurs P, Sylvain C, Lu Y, Shenk KD, Bennett MK. Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome. Blood. 2009 Oct 15;114(16):[http://bloodjournal.hematologylibrary.org/cgi/reprint/114/16/3439 3439-47]. (pmid=19671918) | # Parlati F, Lee SJ, Aujay M, Suzuki E, Levitsky K, Lorens JB, Micklem DR, Ruurs P, Sylvain C, Lu Y, Shenk KD, Bennett MK. Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome. Blood. 2009 Oct 15;114(16):[http://bloodjournal.hematologylibrary.org/cgi/reprint/114/16/3439 3439-47]. (pmid=19671918) | ||
# Deborah J. Kuhn,1 Sally A. Hunsucker,1 Qing Chen,2 Peter M. Voorhees,2 Marian Orlowski,3 Robert Z. Orlowski1. Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors.Blood. 2009 May 7;113(19):[http://bloodjournal.hematologylibrary.org/cgi/reprint/113/19/4667 4667-76]. (pmid=19050304) | # Deborah J. Kuhn,1 Sally A. Hunsucker,1 Qing Chen,2 Peter M. Voorhees,2 Marian Orlowski,3 Robert Z. Orlowski1. Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors.Blood. 2009 May 7;113(19):[http://bloodjournal.hematologylibrary.org/cgi/reprint/113/19/4667 4667-76]. (pmid=19050304) | ||
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# Yasuda H, Hirata S, Inoue K, Mashima H, Ohnishi H, Yoshiba M. Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells. Biochem Biophys Res Commun. 2007 Mar 2;354(1):[http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WBK-4MP5JGJ-C-9&_cdi=6713&_user=16764&_pii=S0006291X06028439&_origin=search&_coverDate=03%2F02%2F2007&_sk=996459998&view=c&wchp=dGLbVzb-zSkWb&md5=203a244a62ad6ef3293be26a9666deef&ie=/sdarticle.pdf 154-9]. (pmid=17214962) | # Yasuda H, Hirata S, Inoue K, Mashima H, Ohnishi H, Yoshiba M. Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells. Biochem Biophys Res Commun. 2007 Mar 2;354(1):[http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WBK-4MP5JGJ-C-9&_cdi=6713&_user=16764&_pii=S0006291X06028439&_origin=search&_coverDate=03%2F02%2F2007&_sk=996459998&view=c&wchp=dGLbVzb-zSkWb&md5=203a244a62ad6ef3293be26a9666deef&ie=/sdarticle.pdf 154-9]. (pmid=17214962) | ||
# Fuchs D, Berges C, Opelz G, Daniel V, Naujokat C. Increased expression and altered subunit composition of proteasomes induced by continuous proteasome inhibition establish apoptosis resistance and hyperproliferation of Burkitt lymphoma cells. J Cell Biochem. 2008 Jan 1;103(1):[http://onlinelibrary.wiley.com/doi/10.1002/jcb.21405/pdf 270-83]. (pmid=17516511) | # Fuchs D, Berges C, Opelz G, Daniel V, Naujokat C. Increased expression and altered subunit composition of proteasomes induced by continuous proteasome inhibition establish apoptosis resistance and hyperproliferation of Burkitt lymphoma cells. J Cell Biochem. 2008 Jan 1;103(1):[http://onlinelibrary.wiley.com/doi/10.1002/jcb.21405/pdf 270-83]. (pmid=17516511) | ||
# Imai S, Kikuchi R, Kusuhara H, Yagi S, Shiota K, Sugiyama Y. Analysis of DNA methylation and histone modification profiles of liver-specific transporters. Mol Pharmacol. 2009 Mar;75(3):[http://molpharm.aspetjournals.org/content/75/3/568.full.pdf+html 568-576] (8/3/10) | |||
# Zhang L, Littlejohn JE, Cui Y, Cao X, Peddaboina C, Smythe WR. Characterization of bortezomib-adapted I-45 mesothelioma cells.Mol Cancer. 2010 May 18;9: [http://www.molecular-cancer.com/content/pdf/1476-4598-9-110.pdf 110](8/10/10) | |||
# Kim SN, Kim NH, Lee W, Seo DW, Kim YK. Histone deacetylase inhibitor induction of P-glycoprotein transcription requires both histone deacetylase 1 dissociation and recruitment of CAAT/enhancer binding protein beta and pCAF to the promoter region. Mol Cancer Res. 2009 May;7(5):[http://mcr.aacrjournals.org/content/7/5/735.full.pdf+html 735-44] pmid=19435809 (9/16/10) | |||
# Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, Chen H, Kong X, Melamed J, Tepper CG, Kung HJ, Brodie AM, Edwards J, Qiu Y. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res. 2009 Mar 15;69(6):[http://cancerres.aacrjournals.org/content/69/6/2305.full.pdf+html 2305-13] pmid=19244107 (9/23/10) | |||
# Maeda T, Irokawa M, Arakawa H, Kuraoka E, Nozawa T, Tateoka R, Itoh Y, Nakanishi T, and Tamai I. Uptake transporter organic anion transporting polypeptide 1B3 contributes to the growth of estrogen-dependent breast cancer. J Steroid Biochem Mol Biol 2010 Oct; 122(4) [http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6T8X-50G6962-1-C&_cdi=5098&_user=16764&_pii=S0960076010002888&_origin=search&_coverDate=10%2F31%2F2010&_sk=998779995&view=c&wchp=dGLbVlW-zSkzS&md5=4e61be9c7a06b0a1c489bad90ac1d2c4&ie=/sdarticle.pdf 180-5](10/7/10) | |||
# van de Steeg E, Wagenaar E, van der Kruijssen CM, Burggraaff JE, de Waart DR, Elferink RP, Kenworthy KE, and Schinkel AH. Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs. J Clin Invest 2010 Aug 2; 120(8) 2942-52. doi:10.1172/JCI42168 pmid:20644253 | |||
# Meyer zu Schwabedissen HE, Tirona RG, Yip CS, Ho RH, Kim RB.Interplay between the nuclear receptor pregnane X receptor and the uptake transporter organic anion transporter polypeptide 1A2 selectively enhances estrogen effects in breast cancer. Cancer Res. 2008 Nov 15;68(22):[http://cancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=19010908 9338-47].PMID: 19010908 (10/28/10) | |||
#Tainton KM, Smyth MJ, Jackson JT, Tanner JE, Cerruti L, Jane SM, Darcy PK, Johnstone RW.Mutational analysis of P-glycoprotein: suppression of caspase activation in the absence of ATP-dependent drug efflux. Cell Death Differ. 2004 Sep;11(9):[http://www.nature.com/cdd/journal/v11/n9/full/4401440a.html 1028-37]. PMID: 15131592 (11/11/10) | |||
#Guo Q, Chen Y, Wu Y. Enhancing apoptosis and overcoming resistance of gemcitabine in pancreatic cancer with bortezomib: a role of death-associated protein kinase-related apoptosis-inducing protein kinase 1. Tumori. 2009 Nov-Dec;95(6):796-803. PMID: 20210246 (11/18/10) | |||
===2009 | ===2009=== | ||
# Fang C, Dean J, Smith JW. A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. Cancer Res. 2007 Oct 1;67(19):[http://cancerres.aacrjournals.org/content/67/19/9039.full.pdf+html 9039-46]. (pmid=17909007) | # Fang C, Dean J, Smith JW. A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. Cancer Res. 2007 Oct 1;67(19):[http://cancerres.aacrjournals.org/content/67/19/9039.full.pdf+html 9039-46]. (pmid=17909007) | ||
# Gomes AV, Young GW, Wang Y, Zong C, Eghbali M, Drews O, Lu H, Stefani E, Ping P. Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics. 2009 Feb;8(2):302-15. (pmid=18931337) | # Gomes AV, Young GW, Wang Y, Zong C, Eghbali M, Drews O, Lu H, Stefani E, Ping P. Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics. 2009 Feb;8(2):302-15. (pmid=18931337) | ||
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# Kimura Y, Yashiroda H, Kudo T, Koitabashi S, Murata S, Kakizuka A, Tanaka K. An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis.Cell. 2009 May 1;137(3):549-59. (pmid=19410548) | # Kimura Y, Yashiroda H, Kudo T, Koitabashi S, Murata S, Kakizuka A, Tanaka K. An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis.Cell. 2009 May 1;137(3):549-59. (pmid=19410548) | ||
# Yi F, Regan L. A novel class of small molecule inhibitors of Hsp90. ACS Chem Biol. 2008 Oct 17;3(10):645-54. Epub 2008 Sep 12.(pmid=18785742) | # Yi F, Regan L. A novel class of small molecule inhibitors of Hsp90. ACS Chem Biol. 2008 Oct 17;3(10):645-54. Epub 2008 Sep 12.(pmid=18785742) | ||
# Oerlemans R, Franke NE, Assaraf YG, Cloos J, van Zantwijk I, Berkers CR, Scheffer GL, Debipersad K, Vojtekova K, Lemos C, van der Heijden JW, Ylstra B, Peters GJ, Kaspers GL, Dijkmans BA, Scheper RJ, Jansen G. Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein. Blood. 2008 Sep 15;112(6):[http://bloodjournal.hematologylibrary.org/cgi/reprint/112/6/2489 2489-99]. (pmid=18565852) | |||
# Sloss CM, Wang F, Liu R, Xia L, Houston M, Ljungman D, Palladino MA, Cusack JC Jr. Proteasome inhibition activates epidermal growth factor receptor (EGFR) and EGFR-independent mitogenic kinase signaling pathways in pancreatic cancer cells. Clin Cancer Res. 2008 Aug 15;14(16):[http://clincancerres.aacrjournals.org/content/14/16/5116.full.pdf+html 5116-23]. (pmid=18698029) | |||
# Voortman J, Checińska A, Giaccone G. The proteasomal and apoptotic phenotype determine bortezomib sensitivity of non-small cell lung cancer cells. Mol Cancer. 2007 Nov 17;6:[http://www.molecular-cancer.com/content/pdf/1476-4598-6-73.pdf 73]. (pmid=18021420) | |||
# Platzer B, Richter S, Kneidinger D, Waltenberger D, Woisetschläger M, Strobl H. Aryl hydrocarbon receptor activation inhibits in vitro differentiation of human monocytes and Langerhans dendritic cells. J Immunol. 2009 Jul 1;183(1):66-74. Epub 2009 Jun 17. (pmid=19535631) | |||
# Shabek N, Herman-Bachinsky Y, Ciechanover A. Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):[http://www.pnas.org/content/106/29/11907.full.pdf+html 11907-12]. (pmid=19581590) | |||
# Comerford KM, Wallace TJ, Karhausen J, Louis NA, Montalto MC, Colgan SP. Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene. Cancer Res. 2002 Jun 15;62(12):[http://cancerres.aacrjournals.org/content/62/12/3387.full.pdf+html 3387-94]. (pmid=12067980) | |||
# Bentires-Alj M, Barbu V, Fillet M, Chariot A, Relic B, Jacobs N, Gielen J, Merville MP, Bours V. NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene. 2003 Jan 9;22(1):[http://www.nature.com/onc/journal/v22/n1/pdf/1206056a.pdf 90-7]. (pmid=12527911) | |||
# Kuhn DJ, Chen Q, Voorhees PM, Strader JS, Shenk KD, Sun CM, Demo SD, Bennett MK, van Leeuwen FW, Chanan-Khan AA, Orlowski RZ. Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma. Blood. 2007 Nov 1;110(9):[http://bloodjournal.hematologylibrary.org/cgi/reprint/110/9/3281 3281-90]. (pmid=17591945) | |||
# Khan MA, Oubrahim H, Stadtman ER. Inhibition of apoptosis in acute promyelocytic leukemia cells leads to increases in levels of oxidized protein and LMP2 immunoproteasome. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11560-5. Epub 2004 Jul 29. (pmid=15284441) | |||
# Xu M, Skaug B, Zeng W, Chen ZJ. A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta. Mol Cell. 2009 Oct 23;36(2):302-14. (pmid=19854138) | |||
# Comerford KM, Cummins EP, Taylor CT. c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia. Cancer Res. 2004 Dec 15;64(24):9057-61. (pmid=15604272) |
Revision as of 09:21, 19 March 2013
Lee Lab Research Meeting
Lee Lab JC
Monthly proteasome meeting schedule
Suggested future papers
Past papers2013
2012
2011
2010
2009
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