LabName:Alcazar: Difference between revisions

From OpenWetWare
Jump to navigationJump to search
No edit summary
No edit summary
(304 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:Alcazar_Lab.tif]]
[[Image:Alcazar_Lab3.jpg|900px]]
<div style="padding: 40px; color: #ffffff; width: 800px">
<div style="padding: 40px; color: #ffffff; width: 900px">
<font face="calibri" style="color:#000000" font size="3">
<font face="calibri" style="color:#000000" font size="3">
----
 


<div id="right menu" style="width:250px; padding: 1em 2em; float:left;">
<div id="right menu" style="width:250px; padding: 1em 2em; float:left;">
{{Template:Alcazar Vertical Menu}}
{{Template:Alcazar Vertical Menu}}
</div>
</div>
<font face="calibri" style="color:#000000" font size="4"><br>
'''''Dear visitor,'''''<br>
<br> Welcome to the webpage of the '''Molecular Genetics of Plant-Environment Interactions (Alcazar Lab)''' at the Department of Biology, Healthcare & Environment of the University of Barcelona. <br><br>
We're a recently created research group that investigates the '''adaptation of plants to local environments'''. We focus on the evolutionary adaptation of plant populations to '''abiotic and biotic stresses''', which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.<br>
<font face="calibri" style="color:#000000" font size="4"><br>
For a more detailed view of our research, please have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.<br><br>
[http://www.fv2017.org XXII Meeting of the Spanish Society of Plant Physiology, BCN 2017 26-29 June] <br>
<font face="helvetica" style="color:#000000" font size="2">
Info currently available in the following languages: <br>
[[http://alcazar.openwetware.org EN]] [[http://alcazar_cat.openwetware.org CAT]] [[http://alcazar_es.openwetware.org ES]]


<font face="calibri" style="color:#000000" font size="6">
<br><br><br><br><br><br><br>
<br><br>
'''''What are we interested in?'''''


----
<font face="helvetica" style="color:#000001" font size="3">
'''1. MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS''' <br>
<font face="calibri" style="color:#000000" font size="4">
<font face="calibri" style="color:#000000" font size="4">
<br>
----
We're interested in genetics of natural variation, population genetics, molecular biology and biochemistry. We want to know how climate change is shaping plant's resistance and tolerance traits under a combined multidisciplinary approach. Our lab undertakes a research approach that looks for the genetic and molecular basis of naturally occurring quantitative variation in biotic and abiotic stress responses, and how these interact with the environment (genotype-by-environment interactions). This multidisciplinary approach will allow a better understanding of the natural evolution of stress pathways in plants and efficient know-how transfer to practical applications.<br>
In our lab, we make use of the extensive natural variation of [https://en.wikipedia.org/wiki/Arabidopsis_thaliana ''Arabidopsis thaliana''] populations to answer key fundamental questions:
 
* '''How plants adapt to local environments including the microbiota?'''
* '''How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?'''
* '''How the environment manipulates immune responses? How this affects the above points?'''
 
 
To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of ''Arabidopsis'' immune-related incompatible hybrids. These are hybrids obtained by crosses of natural ''Arabidopsis'' accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.




For a more detailed view of our research plans, please have a look at our [http://openwetware.org/wiki/Alcazar:Research Research] and [http://openwetware.org/wiki/Alcazar:Publications Publications] sections.
These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.
<br><br>
<br><br><br><br>
----
'''LATEST NEWS'''
<font face="calibri" style="color:#000000" font size="3">
* Are you interested in joining us as PhD or Master student? Contact us by e-mail. [mailto:ralcazar@ub.edu Contact]
<br>
----
<br><br>


'''PREVIOUS ANNOUNCEMENTS'''


<div style="height:150px;width:800px;border:1px solid #ccc;font:16px/26px Calibri;overflow:auto;">
Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.


*'''''October 8th 2012'''''<br>
-> Interessat en realitzar la tesi doctoral o màster al nostre grup? Contacta per e-mail amb nosaltres.<br>
-> [mailto:ralcazar@ub.edu Contact] <br>
*'''''October 4th 2012'''''<br>
New lab webpage version released in OpenWetWare.
</div>
<font face="calibri" style="color:#000000" font size="4">
<br><br>
'''''Línies de recerca'''''


El nostre és un laboratori interessat en l'estudi de les bases genètiques de l'estrés abiòtic i biòtic en plantes, emprant organismes model i espècies d'interés agronòmic, investiguem la variabilitat genètica natural existent en poblacions silvestres. La nostra és una recerca transversal que incorpora genètica de la variabilitat natural, genètica de poblacions, biologia molecular i bioquímica.
Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.  
Els detalls de la nostra recerca i projectes en curs es poden consultar en l'apartat "Research" i "Publications".
<br>




----
----
<br>
<br>
'''''Líneas de investigación'''''
'''2. Polyamines and plant stress protection'''


Nuestro laboratorio tiene como principal línea de investigación el estudio de las bases genéticas del estrés abiótico y biótico. Para ello estudiamos la variabilidad genética natural existente en poblaciones naturales de especies modelo y de interés agronómico. Nuestra investigación es transversal e incluye genética de la variabilidad natural, genética de poblaciones, biología molecular y bioquímica.
Polyamines are small amines present in living organisms. Polyamines are essential for cell viability and have co-evolved and participate in developmental and stress signalling pathways. We’re interested to know how polyamines exert their functions in plants, with a focus on stress tolerance. For this, we’re applying modern genetics, genomics and evolutionary biology. Our final goal is to provide new strategies for crop protection against different types of stress. Read our latest publication  on this topic [http://onlinelibrary.wiley.com/doi/10.1111/pce.12714/abstract here]. Most cited review (>450 times) [http://link.springer.com/article/10.1007%2Fs00425-010-1130-0?LI=true here]
Los detalles de nuestra investigación y proyectos en curso se pueden consultar en las secciones "Research" y "Publications".
<br>




----
<font face="helvetica" style="color:#000000" font size="3">
[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
<font face="calibri" style="color:#000000" font size="3"><br>
LATEST NEWS
28.11.2016 Master offer just posted. Check out link for details. [http://openwetware.org/wiki/Alcazar:Master]




Publications 2016
15/03/2016 In Frontiers Plant Sci: [http://journal.frontiersin.org/article/10.3389/fpls.2016.00401/abstract GWAS analysis for Arabidopsis guazatine tolerance]
22/01/2016 In Plant Cell & Environment:  [http://www.ncbi.nlm.nih.gov/pubmed/26791972 tSpm triggers salinity tolerance in Arabidopsis]
01/02/2016 In Frontiers Plant Sci: [http://journal.frontiersin.org/article/10.3389/fpls.2016.00173/abstract Metabolic profiling of atpao4 mutants under dark induced senescence]
In press: Drought Stress Tolerance in Relation to Polyamine Metabolism in Plants, book chapter in Springer.
''' ACADEMIC PRESS RELEASES'''<br>
[http://www.ub.edu/web/ub/en/menu_eines/noticies/2015/01/020.html? Alcázar Lab work highlighted by the University of Barcelona 20.01.15]<br>
[http://www.ub.edu/noticies/cgi/event.pl?id=62490&noticiaub=FARMACIA Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015]<br>
[http://sefv.net/files/sd_publicaciones/58.pdf Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015]<br>
[http://www.mpipz.mpg.de/4042700/PM_Parker_2015 PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.]<br>
[http://www.ub.edu/web/ub/en/menu_eines/noticies/2013/11/063.html? Arabidopsis semidwarfs: the green revolution in nature] 02.12.2013. University of Barcelona.<br>
[http://www.mpipz.mpg.de/5389/news_publication_619091 Hybrid plants with over-reactive immune system] 17.11.2010. Max Planck Society.
<br>
----
----
<font face="calibri" style="color:#000000" font size="2">
Rubén Alcázar is Ramón y Cajal Researcher at the Department of Natural Products, Plant Biology and Soil Science of the [http://www.ub.edu University of Barcelona].<br>
----
<br>'''Research in Alcázar Lab is supported by:'''


<font face="trebuchet ms" style="color:#000000" font size="2">  
<font face="calibri" style="color:#000000" font size="2"><br>
<br>
* 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
'''Address:'''
* Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
* BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).


Facultat de Farmàcia - Universitat de Barcelona (UB) <br>
Departament de Productes Naturals, Biologia Vegetal i Edafologia<br>
Unitat de Fisiologia Vegetal - Edifici A, 2a Planta <br>
Diagonal 643, 08028 Barcelona<br>
Spain<br>
<br>
----
----
<p>This wiki site is built under [http://www.openwetware.org Openwetware],  an open access movement promoting the sharing of information among researchers.</p>
Lab website is still under construction.
--[[User:Ruben Alcazar|Ruben Alcazar]] 4 October 2012

Revision as of 11:46, 4 December 2016




Dept. Biology, Healthcare & Environment
Section of Plant Physiology
Facultat de Farmàcia, Av. Joan XXIII 27-31
08028 Barcelona, Spain

<html><a href="http://www.revolvermaps.com/?target=enlarge&i=0ewrbw4fec7"><img src="//ra.revolvermaps.com/h/m/a/0/fff600/128/40/0ewrbw4fec7.png" width="156" height="100" alt="Map" style="border:0;"></a>


Dear visitor,

Welcome to the webpage of the Molecular Genetics of Plant-Environment Interactions (Alcazar Lab) at the Department of Biology, Healthcare & Environment of the University of Barcelona.

We're a recently created research group that investigates the adaptation of plants to local environments. We focus on the evolutionary adaptation of plant populations to abiotic and biotic stresses, which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.

For a more detailed view of our research, please have a look at our Research Projects and Scientific Publications sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.

XXII Meeting of the Spanish Society of Plant Physiology, BCN 2017 26-29 June
Info currently available in the following languages:
[EN] [CAT] [ES]









1. MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS


In our lab, we make use of the extensive natural variation of Arabidopsis thaliana populations to answer key fundamental questions:

  • How plants adapt to local environments including the microbiota?
  • How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?
  • How the environment manipulates immune responses? How this affects the above points?


To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of Arabidopsis immune-related incompatible hybrids. These are hybrids obtained by crosses of natural Arabidopsis accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.


These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.


Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.


Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.




2. Polyamines and plant stress protection

Polyamines are small amines present in living organisms. Polyamines are essential for cell viability and have co-evolved and participate in developmental and stress signalling pathways. We’re interested to know how polyamines exert their functions in plants, with a focus on stress tolerance. For this, we’re applying modern genetics, genomics and evolutionary biology. Our final goal is to provide new strategies for crop protection against different types of stress. Read our latest publication on this topic here. Most cited review (>450 times) here



News and Announcements e-Board

LATEST NEWS
28.11.2016 Master offer just posted. Check out link for details. [1]


Publications 2016

15/03/2016 In Frontiers Plant Sci: GWAS analysis for Arabidopsis guazatine tolerance

22/01/2016 In Plant Cell & Environment:  tSpm triggers salinity tolerance in Arabidopsis

01/02/2016 In Frontiers Plant Sci: Metabolic profiling of atpao4 mutants under dark induced senescence

In press: Drought Stress Tolerance in Relation to Polyamine Metabolism in Plants, book chapter in Springer.

ACADEMIC PRESS RELEASES

Alcázar Lab work highlighted by the University of Barcelona 20.01.15
Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015
Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015
PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.
Arabidopsis semidwarfs: the green revolution in nature 02.12.2013. University of Barcelona.
Hybrid plants with over-reactive immune system 17.11.2010. Max Planck Society.



Rubén Alcázar is Ramón y Cajal Researcher at the Department of Natural Products, Plant Biology and Soil Science of the University of Barcelona.



Research in Alcázar Lab is supported by:


  • 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
  • Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
  • BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).