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'''''Dear visitor,'''''<br>
 
<br> Welcome to the webpage of the '''Molecular Genetics of Plant-Environment Interactions (Alcazar Lab)''' at the Department of Biology, Healthcare & Environment of the University of Barcelona. <br><br>
'''''Genetics of Plant-Environment Interactions'''''<br><br>
We're a recently created research group that investigates the '''adaptation of plants to local environments'''. We focus on the evolutionary adaptation of plant populations to '''abiotic and biotic stresses''', which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.<br>
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Dear visitor,<br><br>
For a more detailed view of our research, please have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.<br><br>
Welcome to the webpage of the '''Alcázar Lab''' currently hosted at the University of Barcelona.
[http://www.fv2017.org XXII Meeting of the Spanish Society of Plant Physiology, BCN 2017 26-29 June] <br>
We study the genetic and molecular bases for the '''adaptation of plants to their local environments'''. We focus on the evolutionary adaptation of plant populations to '''abiotic and biotic stresses''', which are major challenges for plant survival. Derived from our basic research, we investigate ways for improving stress protection.<br><br>
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Info currently available in the following languages: <br>
For a more detailed view of our research, please have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. You can follow an updated list of our activities and publications in the NEWS section below.<br>
[[http://alcazar.openwetware.org EN]] [[http://alcazar_cat.openwetware.org CAT]] [[http://alcazar_es.openwetware.org ES]]


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'''CURRENT AREA OF RESEARCH'''
'''MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS''' <br>
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In our lab, we make use of the extensive natural variation of [https://en.wikipedia.org/wiki/Arabidopsis_thaliana ''Arabidopsis thaliana''] populations to answer key fundamental questions:
'''1. Natural variation and evolution of immune resistance genes in plants.''' <br>
 
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* '''How plants adapt to local environments including the microbiota?'''  
Plant resistance to pathogens is an important field of research with direct applications and we study it from an evolutionary, population genetics and molecular view. We currently study the '''molecular bases and evolution of ''Resistance'' genes''' and other loci that condition immune activation. We do so by studying Arabidopsis natural hybrids that exhibit activation of defense and fitness loss. We explore the mechanisms that have naturally evolved in plant populations to resist against pathogens and how the immune receptor repertoire is selected and diversified. At the direct interface between plants and the environment, we study how temperature modulates some plant immune responses.<br>
* '''How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?'''  
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* '''How the environment manipulates immune responses? How this affects the above points?'''
 
 
To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of ''Arabidopsis'' immune-related incompatible hybrids. These are hybrids obtained by crosses of natural ''Arabidopsis'' accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.
 
 
These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.
 
 
Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.
 
 
Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.  
 
 


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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
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LATEST NEWS
05/09/2016. Nazanin A. joins our lab as PhD student in the Biotechnology Program of UB.


  Upcoming event: [http://www.fv2015.org 21th Meeting of the Spanish Society of Plant Physiology, Toledo (Spain) 14-17 June]
  Publications 2016
 
   
  8.01.2015. Kosta joins our Lab as PhD student with an FI grant associated with HI project. Congrats!
  15/03/2016 In Frontiers Plant Sci: [http://journal.frontiersin.org/article/10.3389/fpls.2016.00401/abstract GWAS analysis for Arabidopsis guazatine tolerance]
 
   
  In PLoS Genetics: [http://openwetware.org/wiki/Alcazar:pressDec2014 '''Exploring the maintenance and diversity of plant immunity genes in nature''']
22/01/2016 In Plant Cell & Environment: [http://www.ncbi.nlm.nih.gov/pubmed/26791972 tSpm triggers salinity tolerance in Arabidopsis]
  by Alcázar et al.
 
  [http://www.frontiersin.org/books/Plant_polyamines_in_stress_and_development/340 E-book in Frontiers in Plant Science 2014, by Antonio F. Tiburcio and Rubén Alcázar, Eds.]
   
   
  Editorial article by Ruben Alcazar & A.F. Tiburcio in Frontiers in Plant Science 2014:
  01/02/2016 In Frontiers Plant Sci: [http://journal.frontiersin.org/article/10.3389/fpls.2016.00173/abstract Metabolic profiling of atpao4 mutants under dark induced senescence]
[http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00319/full Plant polyamines in stress and development: an emerging area of research in plant sciences] <br>
   
   
  [http://link.springer.com/article/10.1007/s00425-014-2055-9 '''Review: The Roles of Polyamines during the lifespan of plants:from development to stress''']
  In press: Drought Stress Tolerance in Relation to Polyamine Metabolism in Plants, book chapter in Springer.
Tiburcio AF, Altabella T, Bitrián M and Alcázar R. (2014) Planta 240: 1-18.<br>


''' PRESS RELEASES'''<br>
''' ACADEMIC PRESS RELEASES'''<br>
  [http://www.ub.edu/web/ub/en/menu_eines/noticies/2015/01/020.html? Alcázar Lab work highlighted by the University of Barcelona 20.01.15]<br>
  [http://www.ub.edu/web/ub/en/menu_eines/noticies/2015/01/020.html? Alcázar Lab work highlighted by the University of Barcelona 20.01.15]<br>
  [http://www.ub.edu/noticies/cgi/event.pl?id=62490&noticiaub=FARMACIA Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015]<br>
  [http://www.ub.edu/noticies/cgi/event.pl?id=62490&noticiaub=FARMACIA Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015]<br>
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<br>'''Research in Alcázar Lab is supported by:'''
<br>'''Research in Alcázar Lab is supported by:'''
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Revision as of 05:23, 5 September 2016




Dept. Biology, Healthcare & Environment
Section of Plant Physiology
Facultat de Farmàcia, Av. Joan XXIII 27-31
08028 Barcelona, Spain

<html><a href="http://www.revolvermaps.com/?target=enlarge&i=0ewrbw4fec7"><img src="//ra.revolvermaps.com/h/m/a/0/fff600/128/40/0ewrbw4fec7.png" width="156" height="100" alt="Map" style="border:0;"></a>


Dear visitor,

Welcome to the webpage of the Molecular Genetics of Plant-Environment Interactions (Alcazar Lab) at the Department of Biology, Healthcare & Environment of the University of Barcelona.

We're a recently created research group that investigates the adaptation of plants to local environments. We focus on the evolutionary adaptation of plant populations to abiotic and biotic stresses, which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.

For a more detailed view of our research, please have a look at our Research Projects and Scientific Publications sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.

XXII Meeting of the Spanish Society of Plant Physiology, BCN 2017 26-29 June
Info currently available in the following languages:
[EN] [CAT] [ES]









MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS


In our lab, we make use of the extensive natural variation of Arabidopsis thaliana populations to answer key fundamental questions:

  • How plants adapt to local environments including the microbiota?
  • How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?
  • How the environment manipulates immune responses? How this affects the above points?


To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of Arabidopsis immune-related incompatible hybrids. These are hybrids obtained by crosses of natural Arabidopsis accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.


These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.


Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.


Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.



News and Announcements e-Board

LATEST NEWS
05/09/2016. Nazanin A. joins our lab as PhD student in the Biotechnology Program of UB.
Publications 2016

15/03/2016 In Frontiers Plant Sci: GWAS analysis for Arabidopsis guazatine tolerance

22/01/2016 In Plant Cell & Environment:  tSpm triggers salinity tolerance in Arabidopsis

01/02/2016 In Frontiers Plant Sci: Metabolic profiling of atpao4 mutants under dark induced senescence

In press: Drought Stress Tolerance in Relation to Polyamine Metabolism in Plants, book chapter in Springer.

ACADEMIC PRESS RELEASES

Alcázar Lab work highlighted by the University of Barcelona 20.01.15
Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015
Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015
PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.
Arabidopsis semidwarfs: the green revolution in nature 02.12.2013. University of Barcelona.
Hybrid plants with over-reactive immune system 17.11.2010. Max Planck Society.



Rubén Alcázar is Ramón y Cajal Researcher at the Department of Natural Products, Plant Biology and Soil Science of the University of Barcelona.



Research in Alcázar Lab is supported by:


  • 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
  • Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
  • BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).