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Dept. Biology, Healthcare & Environment
Section of Plant Physiology
Facultat de Farmàcia, Av. Joan XXIII 27-31
08028 Barcelona, Spain

Plant-Environment Interactions and
Molecular Pharming

Our lab studies the genetic and molecular bases for the adaptation of plants to their local environments. We mainly focus on the evolutionary adaptation of plant populations to stress (abiotic and biotic). Derived from our basic research, we investigate ways for improving stress protection and efficient molecular pharming (production of pharmaceutical compounds in plants).

Current projects

Disease resistance in plants

We're currently studying the evolution of NB-LRR immune-receptor genes and other interacting loci that condition defense against evolving pathogens and how this derives in immune-related hybrid incompatibility, an important obstacle in plant breeding. We address these questions using molecular biology, population genetics and biochemical approaches. This research is complemented by the study of the modulation of NB-LRR signaling by temperature which is important under the current climate change predictions.

Natural variation of stress-induced metabolites

We study the genetic bases for the naturally occurring variation of some stress metabolites involved in resistance traits to abiotic and biotic stresses in collaboration with different laboratories. We identify natural compounds which protect plants from stress. Through molecular approaches we improve the resistance of plants to different stresses.

Molecular pharming

We produce proteins of pharmaceutical interest in plants and study ways to improve their productivity under different environments to adapt to the requirements of local climates.

For a more detailed view of our research, have a look at our Research Projects and Scientific Publications sections.
For general public information have a look at +info.

News and Announcements e-Board


A 3-years PhD position (2015-2017) is available in our laboratory to study 
Arabidopsis NB-LRR evolution and interactions with Hyaloperonospora arabidopsidis pathogens.

Interested candidates should send us their CV and two letters of reference by e-mail.

Questions should be addressed to the same e-mail address below.

Application period: 1 July - 15 September 2014

Expected starting date: January 2015



Editorial article of upcoming e-book in Frontiers in Plant Science. Editors: Ruben Alcazar & A.F. Tiburcio.
Plant polyamines in stress and development: an emerging area of research in plant sciences 
The Roles of Polyamines during the lifespan of plants:from development to stress
Tiburcio AF, Altabella T, Bitrián M and Alcázar R. (2014) Planta 240: 1-18.

More news

Ruben Alcazar Lab granted by the Spanish Programme of Scientific and Technical Excellence 2014.

The Faculty | The University | The Campus | Scientific and Technological Centers

Full address: Facultat de Farmacia, Universitat de Barcelona, Unitat de Fisiologia Vegetal. Avda Joan XXIII 27-31, 08028 Barcelona (Spain).
Tel +34 934 024 492 Fax +34 934 029 043

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