Kofuji Lab static webpage 
Another major effort in our laboratory is to study the form and function of intrinsically photosensitive ganglion cells in the mammalian retina. Within the retina of the vertebrate eye there are photoreceptors that capture light to regulate non-image forming visual processes such as day–night rhythms and the narrowing and widening of the pupil. To capture light, these special cells called intrinsically photoreceptive retinal ganglion cells, require pigments called melanopsins, similar to the opsins that the rod and cone cells use for turning light into vision. While the development of cones and rods has been extensively studied, much less is known about the development of melanopsin-expressing ganglion cells. Our lab aims to determine how melanopsin-expressing ganglion cells develop from newborn to adult mouse stages.