Kim
Welcome to the D. H. Kim LaboratoryOur research spans the disciplinary boundaries between biomechanics, nanotechnology, and cell biology with an emphasis on their applications to tissue engineering and regenerative medicine. We focus on the development and applications of biomimetic cell culture models and tissue engineering constructs for studying the intricate interactions between mechanical and biochemical signaling in cell function and fate decisions that are essential for cancer metastasis, tissue repair and regeneration following injury, and various developmental events. Using nanotechnology-based tools in combination with molecular and cell biology approaches, we aim to develope bioinspired tissue engineering models for drug discovery, stem cell-based therapies, disease diagnostics, and medical device development. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health. |
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