Kim

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Deok-Ho Kim, PhD
 Assistant Professor
Department of Bioengineering
& Member, Center for Cardiovascular Biology
Institute of Stem Cell and Regenerative Medicine
University of Washington
Box 355061, Seattle, WA 98195

Welcome to the D. H. Kim Lab

Our research spans the disciplinary boundaries between biomechanics, nanobiotechnology, and cell biology with an emphasis on their applications to tissue engineering and regenerative medicine. We focuses on the development and applications of biomimetic cell culture models and tissue engineering constructs for studying the intricate interactions between mechanical and biochemical signaling in cell/tissue function and fate decisions that are essential for cancer metastasis, tissue repair and regeneration following injury, and various developmental events. Using BioMEMS and nanotechnology-based tools, we would like to also bridge the gap between understanding structure-function relationships at molecular and cellular levels, and being able to utilize bioinspired tissue engineering models for drug discovery, stem cell-based therapies, disease diagnostics, and medical device development. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health.

News

  • 07/30/2010 Professor Kim featured in National Institute of Biomedical Imaging and Bioengineering article on a nanoengineered patch for the damaged heart [1]
  • 05/07/2010 Professor Kim received the Harold M. Weintraub Award [2]
  • 12/17/2009 PNAS paper discussed in Science Daily magazine [3]
  • 05/18/2009 Advanced Functional Materials paper featured as Frontispiece [4]

Recent Publications

  • D.H. Kim, H.J. Lee, Y.K. Lee, J.M. Nam, and A. Levchenko, "Biomimetic nanopatterns as enabling tools for analysis and control of live cells," Advanced Materials, 2010. Pubmed, Hubmed
  • D.H. Kim, E. Lipke, P. Kim, R. Cheong, S. Edmonds, M. Delannoy, K.Y. Suh, L.Tung, and A. Levchenko, "Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs," Proceedings of National Academy of Sciences USA, vol.107, pp. 565-570, 2010. Pubmed, Hubmed
  • D.H. Kim, P. Wong, J.Y. Park, A. Levchenko, and Y. Sun, "Microengineered platform for cell mechanobiology," Annual Review of Biomedical Engineering, vol. 11, pp.203-233, 2009. Pubmed



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