Kevin Matthew McKay Week 5

From OpenWetWare
Revision as of 22:42, 13 February 2013 by Kevin Matthew McKay (talk | contribs) (kegg quesiton)
Jump to navigationJump to search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.

Genes

  • GDH1
    • 2 Homo sapien Homologues:
      • 1NR1 and 1L1F
        • Deficiency in 1L1F causes hyperinsulinism/hymerammonemia syndrome
    • Expression is regulated by carbon sources
      • High expression in presence of glucose and ethanol
  • GDH3
    • 2 Homo sapien Homologues:
      • 1NR1 and 1L1F
        • Deficiency in 1L1F causes hyperinsulinism/hymerammonemia syndrome
    • Expression regulated by carbon sources
      • High expression in presence of ethanol, repressed by glucose
  • GDH2
    • Homo Sapien Homolog:
      • GLUD2
        • Deficiency causes hyperinsulinism
    • Expression regulated by nitrogen catabolite repression and intracellular ammonia levels
  • GLN1
    • Homo sapien homologues:
    • 2OJW and 2QC8
      • Changes in activity of these genes has been linked to Alzheimer's disease
    • Expression regulated by nitrogen source and amino acid limitation
  • GLT1
    • No Homo sapien homolog
    • Expression regulated by glutamate-mediated repression and GLN3P/GCN4P-mediated activation, availability of nitrogen and glutamate, and when amino acids are limiting, GLT1 expression is activated by GCN4P.

KEGG Pathway

  • Central Nitrogen Metabolism
  • All pf the genes in the reference pathway are in the yeast pathway on the website
Retrieved from "https://openwetware.org/mediawiki/index.php?title=Kevin_Matthew_McKay_Week_5&oldid=676223"