Kemp

The Kemp Lab

Redox Systems Biology at Georgia Tech

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We are located in the Wallace H. Coulter Department of Biomedical Engineering administered jointly between Georgia Tech and Emory University School of Medicine. The lab is on the Georgia Tech campus in the Petit Institute for Bioengineering and Bioscience. The lab research focuses on understanding at a systemic level how oxidative stress - induced internally by receptor-initiated ROS generation or by extracellular environment - leads to rapid but transient changes in signal transduction proteins through thiol modification. Our lab uses computational modeling techniques to study how signaling network may be regulated by the resultant changes in activities from these modifications. We also are developing high-throughput biochemical assays to detect and quantify the glutathionylation of proteins.