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=Josh Michener=
==Education==
==Education==
*1st year Bioengineering grad student at Caltech
[[Image:JKMpic.jpg|right|thumb]]
*PhD, 2012, Bioengineering at Caltech
*S.B. 2006, Chemical Engineering and Biology at MIT
*S.B. 2006, Chemical Engineering and Biology at MIT


==Lab history==
==Lab history==
*Rotation student in the [[Smolke Lab]] at [http://www.caltech.edu Caltech]
*NRSA Postdoctoral Fellow in the Marx Lab, Harvard Department of Organismic and Evolutionary Biology
*UROP in the [[Endy Lab]] at [http://web.mit.edu/ MIT], 2005-2006.
*Graduate student in the Smolke Lab, Caltech/Stanford Bioengineering. Collaborated with Frances Arnold (Caltech ChemE) and Jens Nielsen (Chalmers Systems Bio)
*UROP in the Endy Lab at MIT


==Contact Info==
==Contact Info==
Josh Michener<br>
Josh Michener<br>
1200 E. California Blvd.<br>
16 Divinity Ave Room 3082<br>
MC 138-78<br>
Cambridge, MA, 02138<br>
Pasadena, CA, 91125<br>


michener at caltech dot edu
[[Image:Michener-email.png]]


==Past Project==
==Research==
Design and construction of a [[Endy:Screening plasmid|screening plasmid]] to measure the PoPS transfer curve of a [http://parts.mit.edu BioBricks] device.
My research focuses on the combination of rational and evolutionary methods to build, analyze, and optimize metabolic pathways.


==Current thoughts/papers==
==Publications==
[[User:Jkm/Feedback|Metabolic control]]
*'''Michener JK''', Nielsen J, and Smolke CD. Identification and Treatment of Heme Depletion due to Over-expression of a Lineage of Evolved P450 Monooxygenases. PNAS. 2012; 109 (47) 19504-19509. [http://www.pnas.org/content/109/47/19504.abstract]
 
*'''Michener JK''' and Smolke CD. High-throughput enzyme evolution in ''Saccharomyces cerevisiae'' using a synthetic RNA switch. Metab Eng. 2012 Jul; 14(4):306-16. [http://www.sciencedirect.com/science/article/pii/S109671761200047X]
==Random pages==
*'''Michener JK''', Thodey K, Liang JC, Smolke CD. Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metab Eng. 2012 May; 14(3):212-22. [http://www.sciencedirect.com/science/article/pii/S1096717611000942]
[[User:Jkm/Alternate_protocols|Alternate page design]]

Revision as of 10:59, 25 March 2013

Josh Michener

Education

  • PhD, 2012, Bioengineering at Caltech
  • S.B. 2006, Chemical Engineering and Biology at MIT

Lab history

  • NRSA Postdoctoral Fellow in the Marx Lab, Harvard Department of Organismic and Evolutionary Biology
  • Graduate student in the Smolke Lab, Caltech/Stanford Bioengineering. Collaborated with Frances Arnold (Caltech ChemE) and Jens Nielsen (Chalmers Systems Bio)
  • UROP in the Endy Lab at MIT

Contact Info

Josh Michener
16 Divinity Ave Room 3082
Cambridge, MA, 02138

Research

My research focuses on the combination of rational and evolutionary methods to build, analyze, and optimize metabolic pathways.

Publications

  • Michener JK, Nielsen J, and Smolke CD. Identification and Treatment of Heme Depletion due to Over-expression of a Lineage of Evolved P450 Monooxygenases. PNAS. 2012; 109 (47) 19504-19509. [1]
  • Michener JK and Smolke CD. High-throughput enzyme evolution in Saccharomyces cerevisiae using a synthetic RNA switch. Metab Eng. 2012 Jul; 14(4):306-16. [2]
  • Michener JK, Thodey K, Liang JC, Smolke CD. Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metab Eng. 2012 May; 14(3):212-22. [3]