James P. McDonald Week 6

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Week 6 Assignment

  1. Select one of these project topics as what you will present next week.
    • We chose project 2: The chemostat model we’ve worked out does not predict the oxygen use and carbon dioxide production of Figure 1 B. Develop and analyze a model of the chemostat that includes oxygen and carbon dioxide.
  2. Find at least one reference beyond the two terSchure et al papers that will be helpful to your modeling effort. Discuss in your journal the relevance of the reference.
    • Postma, Erik, et al. "Enzymic Analysis of the Crabtree Effect in Glucose-Limited Chemostat Cultures of Saccharomyces Cerevisiae." Applied and Environmental Biology 55.2 (1989): 468-77. [Biological Paper]
    • This paper will be useful because the experiment done in the paper deals with a chemostat containing a yeast population. There is a detailed section of the paper dedicated to the oxygen consumption and carbon dioxide production in the yeast. The information and data presented will be helpful in formulating a model for oxygen consumption and carbon dioxide in our project.
  3. Find a mathematical reference, be it a textbook, a paper, or a website, that is relevant to your project topic. Discuss in your journal the relevance of the reference.
    • Bailey, J.E. "Mathematical Modeling and Analysis in Biochemical Engineering: Past Accomplishments and Future Opportunities." Biotechnology Progress 14.1 (1998): 8-20. [Mathematical Paper]
    • This paper will be useful because it talks about mathematical modeling in steady state conditions such as in chemostats. The paper specifically touches on chemostats involving yeast populations. I have trouble with the modeling so this paper should prove to be a good resource when I am modeling our project.

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