James P. McDonald Week 5

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**GLN1: expression regulated by nitrogen source and amino acid limitation
**GLN1: expression regulated by nitrogen source and amino acid limitation
**GLT1: expression regulated by nitrogen source
**GLT1: expression regulated by nitrogen source
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*There are 56 pathways listed in the database that L-glutamate participates
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*There are 56 pathways listed in the database that L-glutamate participates in
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*Pathway
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*Pathway:
**[http://pathway.yeastgenome.org/YEAST/NEW-IMAGE?type=PATHWAY&object=PWY3O-13 SGD Pathway]
**[http://pathway.yeastgenome.org/YEAST/NEW-IMAGE?type=PATHWAY&object=PWY3O-13 SGD Pathway]
**[[image:SGD_Pathway.jpg]]
**[[image:SGD_Pathway.jpg]]

Revision as of 02:31, 14 February 2013

Contents

Exploring Pathway Databases

Saccharomyces Genome Database

  • GDH2 has a homolog in humans. A deficiency of the human homologs, GLUD1 and GLUD2, has been known to cause hyperinsulinism-hyperammonemia syndrome and various neurological disorders.
  • Gene Expression Regulation:
    • GDH1: expression regulated by nitrogen and carbon sources
    • GDH3: expression regulated by nitrogen and carbon sources
    • GDH2: expression sensitive to nitrogen catabolite repression and intracellular ammonia levels
    • GLN1: expression regulated by nitrogen source and amino acid limitation
    • GLT1: expression regulated by nitrogen source
  • There are 56 pathways listed in the database that L-glutamate participates in
  • Pathway:

KEGG

  • KEG Pathway
  • image:KEGG_Pathway_edit.jpg
  • The information provided in KEGG is similar to SGD but KEGG includes 3-D structures of the enzymes and AA and NT sequences.

Reactome

Class Links

Journal Entries and Assignments

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