James P. McDonald Week 5: Difference between revisions

From OpenWetWare
Jump to navigationJump to search
(→‎KEGG: added last kegg question)
Line 22: Line 22:


===Reactome===
===Reactome===
*[http://www.reactome.org/entitylevelview/PathwayBrowser.html#DB=gk_current&FOCUS_SPECIES_ID=68322&FOCUS_PATHWAY_ID=2666285&ID=2659808 Reactome Pathway]
*[[image:Reactome_Pathway_edit.jpg]]


{{James P. McDonald}}
{{James P. McDonald}}


[[Category:BIOL398-03/S13]]
[[Category:BIOL398-03/S13]]

Revision as of 00:23, 14 February 2013

Exploring Pathway Databases

Saccharomyces Genome Database

  • GDH2 has a homolog in humans. A deficiency of the human homologs, GLUD1 and GLUD2, has been known to cause hyperinsulinism-hyperammonemia syndrome and various neurological disorders.
  • Gene Expression Regulation:
    • GDH1: expression regulated by nitrogen and carbon sources
    • GDH3: expression regulated by nitrogen and carbon sources
    • GDH2: expression sensitive to nitrogen catabolite repression and intracellular ammonia levels
    • GLN1: expression regulated by nitrogen source and amino acid limitation
    • GLT1: expression regulated by nitrogen source
  • There are 56 pathways listed in the database that L-glutamate participates
  • Pathway

KEGG

  • KEG Pathway
  • The information provided in KEGG is similar to SGD but KEGG includes 3-D structures of the enzymes and AA and NT sequences.

Reactome

Class Links

Journal Entries and Assignments

Retrieved from "https://openwetware.org/mediawiki/index.php?title=James_P._McDonald_Week_5&oldid=676241"