James P. McDonald Week 5

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
(added template and category)
(answered first 3 questions)
Line 1: Line 1:
 +
==Exploring Pathway Databases==
 +
 +
===Saccharomyces Genome Database===
 +
*GDH2 has a homolog in humans. A deficiency of the human homologs, GLUD1 and GLUD2, has been known to cause hyperinsulinism-hyperammonemia syndrome and various neurological disorders.
 +
*Gene Expression Regulation:
 +
**GDH1: expression regulated by nitrogen and carbon sources
 +
**GDH3: expression regulated by nitrogen and carbon sources
 +
**GDH2: expression sensitive to nitrogen catabolite repression and intracellular ammonia levels
 +
**GLN1: expression regulated by nitrogen source and amino acid limitation
 +
**GLT1: expression regulated by nitrogen source
 +
*There are 56 pathways listed in the database that L-glutamate participates
 +
*Pathway
 +
**[[http://pathway.yeastgenome.org/YEAST/NEW-IMAGE?type=PATHWAY&object=PWY3O-13|SGD Pathway]]
 +
**[[image:SGD_Pathway.jpg]]
 +
 +
===KEGG===
 +
 +
===Reactome===
 +
{{James P. McDonald}}
{{James P. McDonald}}
[[Category:BIOL398-03/S13]]
[[Category:BIOL398-03/S13]]

Revision as of 01:38, 14 February 2013

Contents

Exploring Pathway Databases

Saccharomyces Genome Database

  • GDH2 has a homolog in humans. A deficiency of the human homologs, GLUD1 and GLUD2, has been known to cause hyperinsulinism-hyperammonemia syndrome and various neurological disorders.
  • Gene Expression Regulation:
    • GDH1: expression regulated by nitrogen and carbon sources
    • GDH3: expression regulated by nitrogen and carbon sources
    • GDH2: expression sensitive to nitrogen catabolite repression and intracellular ammonia levels
    • GLN1: expression regulated by nitrogen source and amino acid limitation
    • GLT1: expression regulated by nitrogen source
  • There are 56 pathways listed in the database that L-glutamate participates
  • Pathway

KEGG

Reactome

Class Links

Journal Entries and Assignments

Personal tools