IGEM:UIUC/Software/2010/2010/03/10: Difference between revisions

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(Autocreate 2010/03/10 Entry for IGEM:UIUC/Software/2010)
 
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==Entry title==
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==March 10, 2010==
===First Entry===
* Information about Dijkstras -- searches network to get from one network to another
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* Many metabolic pathways
** FBA - flux balance analysis
** COBRA - (matlab) -- links things
** KEGG - pathway maths
** Environmental strains? - secondary enzymes
** Crossing over pathways -- KEGG map -- galactose metabolism pathway -- enzymes, collecting compounds - group the enzymes to compounds
*** Things can cross over and can be done in a different way
*** They highlighted (competing people) -- intermediate pathways
** Metabolic
* Continue code -  pathway - nodes = products , lines = reactions (IMP)
** Fewest constraints -- tried
** Problems -- compounds are isolated -- some only connected in one way
** Shortest path algorithm -- defined edge of dot product numbers we know and numbers we give it -- weights you define and facts (number of things)  = a number == length of the edge  (bad facts) --
** Number of connectivity -- about 100 -- how many different compounds is each connected too -- each on its own scale -- dot matrices don't line up .. [0  1] . [~1  100]
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** How pathway effects cell (host)
*** Host = hypothetical host
* '''TO BE IMPRESSIVE AT IGEM'''
** Gotta be impressive! -- tweak  a lot
** Add massive new feature -- say how pathway would effect overall system
** Many metabolic -- gotta really do something with it
* Biobrick -
** Freiburg
* Look at previous iGEM -- iGEM website  -- Francis does this
** Do use biobricks in some way
* Google group -- check
* Completely Different:
** Working with the wetlab -
*** model their current project?
**** Cellular logic design - takes substance and fluoresces colors depending on two different things - working toward cellular computation -- (0s and 1s) -- more analog -- end goal: computation of things within a cell -- direct diseases
***** Don't fluoresce, next step: release -- outputs and inputs produce things -- and, or gates
***** Designer tool -- EC majors -- lay out-- coverts to biobricks
***** See IBE person
** Analyzing wetlab team -- give them a helping hand -- make smoother process
*** Different interference sequence in wire diagram -- and: promoter promotes certain region which upreglates something else which gives you a specfic fluorescence
**** Do a small model -- help our team by simulating
**** OR as just a side project
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* Must come up with a way to keep track of all journals read -- for citing.
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'''Homework''' - look at all the old projects (software projects) -- and look up biobricks - go onto iGEM websites and check the schedule post -- color coated by category. Go through judging requirements
** Modeling, safety, biobricks -- force your really cool idea into iGEM judging
** Split up stuff to collect research -- Anna -- metabolic pathways,
** Look up research from previous years


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[[category:OWWLabNotebookV1]]
[[category:OWWLabNotebookV1]]

Revision as of 16:35, 29 May 2010

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