IGEM:Melbourne/2008/BCModelling/ModelDevelopment: Difference between revisions
From OpenWetWare
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 11: | Line 11: | ||
*''connections'' - this is the first part of the modelling to get the connections right both biologically and theoretically. Jason and Dave are doing this for the linear and binary model respectively. Include as much as possible, remember to employ special cases to be able to simplify the model when necessary and ensure complexity when required. | *''connections'' - this is the first part of the modelling to get the connections right both biologically and theoretically. Jason and Dave are doing this for the linear and binary model respectively. Include as much as possible, remember to employ special cases to be able to simplify the model when necessary and ensure complexity when required. | ||
*''parameters'' - obtain the right parameters for Hill functions, Kd, degradation rates, RL/RK binding constants, and other parameters for more complex models (such as [ | *''parameters'' - obtain the right parameters for Hill functions, Kd, degradation rates, RL/RK binding constants, and other parameters for more complex models (such as [REFshae 1985|shae 1985], statisical mechanics model for promoter activity) | ||
*''break apart'' - need to obtain | *''break apart'' - need to obtain | ||
Revision as of 05:52, 16 May 2008
Calibration
Strategy for completion described below
- connections - this is the first part of the modelling to get the connections right both biologically and theoretically. Jason and Dave are doing this for the linear and binary model respectively. Include as much as possible, remember to employ special cases to be able to simplify the model when necessary and ensure complexity when required.
- parameters - obtain the right parameters for Hill functions, Kd, degradation rates, RL/RK binding constants, and other parameters for more complex models (such as [REFshae 1985|shae 1985], statisical mechanics model for promoter activity)
- break apart - need to obtain
- iterate
- real
- ideal
