IGEM:MIT/2005/Future direction: Difference between revisions

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::Input any external signal in a controlled manner
::Input any external signal in a controlled manner
:How to improve:
:How to improve:
:Modularity
::Modularity
::ToxR needs to be "extended to outer membrane
:::ToxR needs to be "extended to outer membrane
::Test with primary and secondary antibody setup
:::Test with primary and secondary antibody setup
::Use antigen that is not already a dimer
:::Use antigen that is not already a dimer
::Test modularity by using different antigens, signal processing systems and actuators
:::Test modularity by using different antigens, signal processing systems and actuators
:Usability
::Usability
::Activity must be characterized
:::Activity must be characterized
::Could be tested in other chassis
:::Could be tested in other chassis
::Feedback mechanisms and other downstream stuff to demonstrate usability
:::Feedback mechanisms and other downstream stuff to demonstrate usability
:Overall goal to make tool to be use in other systems
:System Applications:
:Applications:
::Biosensor
::Biosensor
:::environmental application -- test for contaminates
:::environmental application -- test for contaminates
::Research tools
::Research tools
:::Replace other antibody sensors (western blots), cell-cell signaling
:::Replace other antibody sensors (western blots), cell-cell signaling
:Impact
:Long term impact
::extending and easing research in synthetic biology
::extending and easing research in synthetic biology

Latest revision as of 06:48, 18 October 2005

What we have done:
Make a modular tool
Input any external signal in a controlled manner
How to improve:
Modularity
ToxR needs to be "extended to outer membrane
Test with primary and secondary antibody setup
Use antigen that is not already a dimer
Test modularity by using different antigens, signal processing systems and actuators
Usability
Activity must be characterized
Could be tested in other chassis
Feedback mechanisms and other downstream stuff to demonstrate usability
System Applications:
Biosensor
environmental application -- test for contaminates
Research tools
Replace other antibody sensors (western blots), cell-cell signaling
Long term impact
extending and easing research in synthetic biology