IGEM:Imperial/2010/Fast Response module

From OpenWetWare

< IGEM:Imperial/2010
Revision as of 11:11, 23 September 2010 by Benjamin Miller (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search

2 components systems
logic gate
Vibrio cholera

Idea 1

The first idea, that seems to be feasible considering all the components, is the one below:

Image:OmpR system pic.jpg

This is a bacterial two component system. On recieving of a signal, the Env Z receptor autophosphorylates. The phosphate is then passed on the respond element, a transcription factor called OmpR. OmpR is a molecule found naturally downstream of the signalling cascade from the EnvZ receptor. On phosphorylation the OmpR-P dimerise. Since each OmpR is fused with a split protease, when the OmpRs come together, the split protease (TEV) domains come together. This produces the active protease.


  • all about EnvZ [1]
  • all about OmpR [2]
Personal tools