IGEM:Imperial/2010: Difference between revisions

From OpenWetWare
Jump to navigationJump to search
mNo edit summary
No edit summary
 
(42 intermediate revisions by 7 users not shown)
Line 1: Line 1:
<div id="mainpage">
{{Imperial2010/Header}}
“More than two billion people around the world live with unrelenting
illness due to parasites” - WHO Director General Lee Jong-wook.
Synthetic biology offers great opportunity for biosensors, however
current designs require hours before useful output. To tackle this
issue in the field, it's crucial that our project can respond in
minutes, hence we have engineered a fast, modular sensor framework.
This allows detection of a range of different parasites, and may also
be used as an environmental tool for mapping their spread. We have
developed two new technologies that enable our modular input/output -
a novel cell surface biosensor, customisable for specific parasitic
proteases, linked through quorum-sensing to a new 'fast-response'
module capable of producing a detectable output in minutes. To
demonstrate the concept, we've designed and fabricated B. subtilis to
give a striking colour readout upon detecting the waterborne
Schistosoma parasite which affects 200 million people worldwide.


<hr class=divider>
{| style="width:100%; height:100px"
| width="30%" rowspan=1 | [[Image:Igemlogo.png‎|130px]]                                           
| width="40%"| [[Image:ImperialCollege CentenaryLogo.png|280px]]
|}
<hr class=divider>


{| cellspacing="5"
<span style="font-size:2em;color:#555555;">This website is not our main website! Please head to
|width="200px" class="blue" |
[http://2010.igem.org/Team:Imperial_College_London http://2010.igem.org/Team:Imperial_College_London] for the full details.</span>
<!-- RESOURCES HEADER with edit link-->
<h3><html>
<img src="http://openwetware.org/images/b/b9/Icon_board.png" alt="Resources">
</html>Resources</h3>
<hr/>
<!-- END RESOURCES HEADER-->


'''About our iGEM summer'''
* [[IGEM:Imperial/2010/Calendar | Calendar]]
* [[IGEM:Imperial/2010/Projects | Brainstorming]]
* [[IGEM:Imperial/2010/Journal_Club | Journal Club]]
* [[IGEM:Imperial/2010/Modelling | Modelling]]
'''Synthetic Biology related'''
* [http://www.syntheticbiology.org sytheticbiology.org]
* [http://openwetware.org/wiki/Imperial_College/Courses/Spring2008/Synthetic_Biology Imperial Synthetic Biology Course]
|width="350px" class="white" |
<!-- INFORMATION HEADER with edit link-->
<h3><html>
<img src="http://openwetware.org/images/e/e2/Icon_info.png" alt="INFORMATION" border="0">
</html>News and Highlights</h3>
<hr/>
<!-- END INFORMATION HEADER with edit link-->
=== Breaking News ===
* Monday July 5th Start of iGEM 2010
----
===<html><body><font COLOR="green">>>> Getting Started <<<</body></font></html>===
* '''Get an [http://www.openwetware.com OpenWetWare Account]'''
* '''[[IGEM:Imperial/2010/Projects|Brainstorming]]'''
*'''[[User:Ben_Yi_Tew/temp | Guide to editing the OWW Wiki]]'''
|width="220px" class="blue" |
<!-- PEOPLE HEADER with edit link-->
<h3><html>
<img src="http://openwetware.org/images/3/39/Icon_groups.png" alt="People">
</html>People</h3>
<hr/>
<!-- END PEOPLE HEADER with edit link-->
<!--The Imperial iGEM team consists of nine undergraduate students working fulltime during summer 2008 on engineering a biological system.  In addition, we have a number of graduate student and faculty advisors.-->
'''Students'''
* [[User:Piotr_D._Faba | Piotr D Faba]]
* [[User:Harriet_D._Gliddon | Harriet D Gliddon]]
* [[User:Nicolas_Kylilis | Nicolas Kylilis]]
* [[User:Benjamin_Miller | Benjamin Miller]]
* [[User:Anita_Nguyen | Anita Nguyen]]
* [[User:Wolfgang_Pernice | Wolfgang Pernice]]
* [[User:Kyasha_Sri_Ranjan | Kyasha Sri Ranjan]]
* [[User:Madeline_Rounds | Madeline Rounds]]
* [[User:A._Florian_Sessler | A Florian Sessler]]
* [[User:Kirill_Shkura | Kirill Shkura]]
'''Advisors'''
* [[User:Chris_D_Hirst | Chris D Hirst]]
|}
</div>


__NOEDITSECTION__
__NOEDITSECTION__

Latest revision as of 13:26, 24 October 2010

<html> 

<head>
 <meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
 <script type="text/javascript" src="http://ajax.googleapis.com/ajax/libs/jquery/1.4.2/jquery.min.js"></script>
 <script type="text/javascript">
  $(document).ready(function(){

$(function(){ 

var path = location.pathname.substring(1);
if ( path )
$('#headover ul li a[href$="' + path + '"]').addClass("curlink").css("color","#ea8828");;
var vCurlink = $('#headover ul li a[href$="' + path + '"]').attr("id");
$('#'+vCurlink+'.listhead').addClass('curlink').css("color","#444444");

});

$('#menuback').mouseover(function() { 

$('#headover').stop().animate({height:'150px',top:'0px'},1000);

});

$('#menu').mouseleave(function() { 

$('.listhead').not('.curlink').css("color","#ffffff");
$('.listmain').not('.curlink').css("color","#dddddd");
$('#headover ul').fadeOut(200);
$('#headover').stop().animate({height:'50px',top:'100px'},1000);

});

$('.listhead').mouseover(function(){ 

$('.listhead').not('.curlink').css("color","#ffffff");
$(this).css("color","#444444");
$('#headover ul').css("display","none");
var vActive = $(this).attr("id");
$('.'+vActive).stop().fadeIn(200);

});

$('.listmain').mouseover(function(){ 

$('.listmain').not('.curlink').css("color","#dddddd");
$(this).css("color","#ea8828");

});

$('#headover').mouseleave(function(){ 

$('.listmain').not('.curlink').css("color","#dddddd");

}); 

  });
 </script>
 <style type="text/css">

  .firstHeading {
   display: none;}

  #content {
   width: 900px;
   font-family: helvetica, arial, sans-serif;
   color: #555555}

  #title {
   width:900px;
   height:50px;
   position: relative;
   top: 0px;
   left: 0px;}

  #implogo {
   width:190px;
   height:50px;
   position: absolute;
   top: 0px;
   left: 20px;
   background-image:url(http://openwetware.org/images/c/c9/Imperialigemimplogo.jpg);}

  #igemlogo {
   width:84px;
   height:50px;
   position:absolute;
   top:0px;
   left:260px;
   background-image:url(http://openwetware.org/images/9/9c/Imperialigemigemlogo.jpg);}

  #csynbilogo {
   width:205px;
   height:50px;
   position:absolute;
   top:0px;
   left:394px;
   background-image:url(http://openwetware.org/images/a/ac/Imperialigemcsynbilogo.jpg);}

  #menu {
   width:900px;
   height:150px;
   position: relative;
   top: 20px;
   left: 0px;}

  #menuback {
   width:100px;
   height:150px;
   position: absolute;
   top: 0px;
   left: 0px;
   background-color: #ea8828}

  #headpic {
   width:800px;
   height:150px;
   position: absolute;
   top: 0px;
   left: 100px;
   background-image: url('http://openwetware.org/images/5/54/Imperialigemheadone.jpg'); }

  #headover {
   width: 800px;
   height:50px;
   position: absolute;
   top: 100px;
   left: 0px;
   background: url(http://openwetware.org/images/d/d8/Imperialigemheadoverone.png) 0px 0px no-repeat; }

  a {
   outline:none;}

  #headtit{
   font-family: helvetica, arial, sans-serif;
   font-size: 1.2em;
   color: #ffffff;
   position: absolute;
   top: 0.5em;
   right: 1.4em;}

  .dark{
   color: #dddddd;}

  .highlight{
   color: #ea8828;}

  #menulist{
   position: absolute;
   top: 16px;
   left: 3px;
   list-style: none;}

  #menulist li{
   height: 30px;
   }

  #menulist li a{
   font-weight: 100;
   font-size: 1.2em;
   text-decoration: none;
   font-family: helvetica, arial, sans-serif;
   color: #ffffff;}

  #headover ul{
   list-style: none;
   display: none;
   position: absolute;
   top: 1.2em;
   left: 0.2em;
   }

  #headover ul ul{
   position: absolute;
   top:-0.2em;
   left: 15em;}

  #headover ul li{
   height: 2.4em;
   }

  #headover ul li a{
   font-weight: 100;
   font-size: 1.2em;
   text-decoration: none;
   font-family: helvetica, arial, sans-serif;
   color: #dddddd;}

 </style>
</head>
<body>
 <div id='title'>
  <div id='implogo'>
  </div>
  <div id='igemlogo'>
  </div>
  <div id='csynbilogo'>
  </div>
 </div>
 <div id='menu'>
  <div id='menuback'>
   <ul id='menulist'>
    <li><a href='#' class='listhead' id='project'>Project</a></li>
    <li><a href='#' class='listhead' id='plan'>Plan</a></li>
    <li><a href='#' class='listhead' id='results'>Results</a></li>
    <li><a href='#' class='listhead' id='extra'>Extra</a></li>
   </ul>
  </div>
  <div id='headpic'>
   <div id='headover'>
    <p id='headtit'>Parasight<span class='dark'> &nbsp;<span class='highlight'>|</span>&nbsp;&nbsp;Parasite detection with a rapid response</span></p>
    <ul class='project'>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010' class='listmain' id='project'>Overview</a></li>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Detection_module' class='listmain' id='project'>Detection Module</a></li>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Fast_Response_module' class='listmain' id='project'>Fast Response Module</a></li>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Output_module' class='listmain' id='project'>Output Module</a></li>
     <ul class='project'>
      <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Ethics' class='listmain' id='project'>Ethics</a></li>
      <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Parts' class='listmain' id='project'>Parts</a></li>
      <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Papers' class='listmain' id='project'>Papers</a></li>
     </ul>
    </ul>
    <ul class='plan'>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Strategy' class='listmain' id='plan'>Strategy</a></li>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Parts/Synthesis' class='listmain' id='plan'>Synthesis</a></li>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Lab_Work' class='listmain' id='plan'>Lab Work</a></li>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Protocol' class='listmain' id='plan'>Protocol</a></li>
     <ul class='plan'>
      <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Modelling' class='listmain' id='plan'>Modelling</a></li>
     </ul>
    </ul>
    <ul class='results'>
     <li><a href='#' class='listmain' id='results'>Under Construction</a></li>
    </ul> 
    <ul class='extra'>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Projects' class='listmain' id='extra'>Brainstorming</a></li>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Journal_Club' class='listmain' id='extra'>Journal Club</a></li>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Movie_Night' class='listmain' id='extra'>Movie Night</a></li>
     <li><a href='http://openwetware.org/wiki/IGEM:Imperial/2010/Judging_Criteria' class='listmain' id='extra'>Judging Criteria</a></li>
    </ul> 
   </div>
  </div>
 </div>
</body>

</html> <html> 

<head>
 <style type="text/css">
  #blank {
   height:40px;
   width: 900px;
 </style>
</head>
<body>
 <div id="blank">
 </div>
</body>

</html> “More than two billion people around the world live with unrelenting illness due to parasites” - WHO Director General Lee Jong-wook. Synthetic biology offers great opportunity for biosensors, however current designs require hours before useful output. To tackle this issue in the field, it's crucial that our project can respond in minutes, hence we have engineered a fast, modular sensor framework. This allows detection of a range of different parasites, and may also be used as an environmental tool for mapping their spread. We have developed two new technologies that enable our modular input/output - a novel cell surface biosensor, customisable for specific parasitic proteases, linked through quorum-sensing to a new 'fast-response' module capable of producing a detectable output in minutes. To demonstrate the concept, we've designed and fabricated B. subtilis to give a striking colour readout upon detecting the waterborne Schistosoma parasite which affects 200 million people worldwide.


This website is not our main website! Please head to http://2010.igem.org/Team:Imperial_College_London for the full details.




<html> <!-- Start of StatCounter Code --> <script type="text/javascript" language="javascript"> var sc_project=2128467; var sc_invisible=1; var sc_partition=19; var sc_security="0b7ca9e0"; </script>

<script type="text/javascript" language="javascript" src="http://www.statcounter.com/counter/frames.js"></script><noscript><a href="http://www.statcounter.com/" target="_blank"><img src="http://c20.statcounter.com/counter.php?sc_project=2128467&amp;java=0&amp;security=0b7ca9e0&amp;invisible=1" alt="web tracker" border="0"></a> </noscript> <!-- End of StatCounter Code --> </html>

Retrieved from "https://openwetware.org/mediawiki/index.php?title=IGEM:Imperial/2010&oldid=466869"