IGEM:IMPERIAL/2006/project/Oscillator/project browser

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!width="20%" style="background:#FF9966"|Final System
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!width="20%" style="background:#2171B8"|Final System
! colspan="8" width="80%" style="background:#CCCCFF"| [[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Full_System | Molecular Prey-Predator Oscillator ]] <br>[[Image:Oscillator_Icon.PNG|40px]]
! colspan="8" width="80%" style="background:#CCCCFF"| [[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Full_System | Molecular Prey-Predator Oscillator ]] <br>[[Image:Oscillator_Icon.PNG|40px]]
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!width="20%" style="background:#FF9966"|Final Constructs
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!width="20%" style="background:#2171B8"|Final Constructs
! colspan="3" width="40%" style="background:#CCCCFF"| [[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Prey_Construct | Prey construct ]] <br>[[Image:J37015page.JPG‎|180px]]
! colspan="3" width="40%" style="background:#CCCCFF"| [[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Prey_Construct | Prey construct ]] <br>[[Image:J37015page.JPG‎|180px]]
! colspan="5" width="40%" style="background:#CCCCFF"|  
! colspan="5" width="40%" style="background:#CCCCFF"|  
[[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Predator_Construct | Predator construct ]] <br> [[Image:J37036 parts pic.PNG|150px]]
[[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Predator_Construct | Predator construct ]] <br> [[Image:J37036 parts pic.PNG|150px]]
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!width="20%" style="background:#FF9966"|Test Constructs  
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!width="20%" style="background:#2171B8"|Test Constructs  
! colspan="1" width="20%" style="background:#CCCCFF"| [[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Test_Sensing_Prey_Construct | Test Sensing Prey ]] [[Image:T9002.JPG|130px]]
! colspan="1" width="20%" style="background:#CCCCFF"| [[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Test_Sensing_Prey_Construct | Test Sensing Prey ]] [[Image:T9002.JPG|130px]]
! colspan="2" width="20%" style="background:#CCCCFF"| [[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Test_Prey_Construct | Test Prey production ]] [[Image:J37015page.JPG‎|180px]]
! colspan="2" width="20%" style="background:#CCCCFF"| [[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Test_Prey_Construct | Test Prey production ]] [[Image:J37015page.JPG‎|180px]]

Revision as of 13:05, 30 October 2006

Molecular Prey-Predator Oscillator

Project browser

Final System Molecular Prey-Predator Oscillator
Final Constructs Prey construct

Predator construct

Test Constructs Test Sensing Prey Test Prey production Test Sensing Predator Test Killing Predator

Motivations

Oscillators are a fundamental building block in many fields of engineering and are a widespread phenomenon in biology. Building a biological oscillator is thus a critical step forward in the field of Synthetic Biology.


Engineering a Molecular Predation Oscillator, the iGEM project 2006 of Imperial College London, provides a new approach to creating a stable biological oscillator: It follows an engineering-based cycle of specification, design, modelling, implementation and testing/validation. The innovative design of the oscillator relies on predator-prey dynamics based on the Lotka-Volterra model.

Detail theoretical modelling showing how our system might be able to work! Click here

Achievements

Following the design of the oscillator, a full theoretical analysis and detailed computer modelling of the Lotka-Volterra dynamics was carried out. These studies showed that it is theoretically possible to provide a stable oscillator. Because all components as well as the overall oscillator were modelled, its behaviour could be accurately predicted. Our team successfully built the functional parts, thus providing the building blocks for the final oscillator. All parts created were experimentally tested and their characterization could be used to feedback information into the modelling.

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