IGEM:Harvard/2006/Brainstorming with William: Difference between revisions
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Back to [[IGEM:Harvard/2006/Brainstorming|brainstorming]] | Back to [[IGEM:Harvard/2006/Brainstorming|brainstorming]] | ||
==What are the synonyms for containers?== | |||
'''Use these terms for web searches investigating potential applications of molecular containers''' | |||
*Capsules | |||
*Containers | |||
*Encapsulation | |||
*Vaults | |||
*Viruses | |||
*Vehicles | |||
*Vesicles | |||
*Liposomes | |||
*Vessels | |||
*Boxes | |||
*Compartments | |||
<br> | |||
==What are the enabling features? (Can be optional features)== | |||
'''These are general capabilities for which there may or may not exist demand outside the field''' | |||
*Rigid or defined structure | |||
*Getting things in and out | |||
*Non-porous → doesn't leak in or out | |||
*Allows one to maintain different microenvironments (inside versus outside) | |||
*'''Allows multiplexed microenvironments''' | |||
*Selective permeability | |||
*Ability to fuse or separate | |||
*Caging and release | |||
*Controlled release | |||
*Specific targeting of container to destination | |||
*Robotics | |||
<br> | |||
==What are potential applications for containers?== | |||
'''These are applications for which one suspects there may be demand in the outside community''' | |||
*Drug and gene delivery | |||
**Issues | |||
***Slow down the clearance time in plasma and intracellularly | |||
***Size of pores | |||
***Getting into cell | |||
*Directed evolution (compartmentalized selections) | |||
*Chemical synthesis | |||
**Increase effective concentration of reactants | |||
**Using multiplexing for combinatorial synthesis | |||
*Protein folding (chaperone) | |||
*Capture and stabilization of multiprotein complexes | |||
*Marker scavenging | |||
*Cell sorting (gattaca technology) | |||
<br> | |||
==What are demand-meeting applications for containers?== | |||
'''Can move items from the "potential applications" list down to this list when you can find specific examples (i.e. names of molecules involved) where a demand exists for this application; for many people, this is the only list that matters''' | |||
<br> | |||
==How exactly to implement container and lid?== | |||
<br> | |||
<br> | |||
Biotin/streptavinin docking? | Biotin/streptavinin docking? | ||
Back to [[IGEM:Harvard/2006/Brainstorming|brainstorming]] | Back to [[IGEM:Harvard/2006/Brainstorming|brainstorming]] |
Latest revision as of 14:20, 18 June 2006
Back to brainstorming
What are the synonyms for containers?
Use these terms for web searches investigating potential applications of molecular containers
- Capsules
- Containers
- Encapsulation
- Vaults
- Viruses
- Vehicles
- Vesicles
- Liposomes
- Vessels
- Boxes
- Compartments
What are the enabling features? (Can be optional features)
These are general capabilities for which there may or may not exist demand outside the field
- Rigid or defined structure
- Getting things in and out
- Non-porous → doesn't leak in or out
- Allows one to maintain different microenvironments (inside versus outside)
- Allows multiplexed microenvironments
- Selective permeability
- Ability to fuse or separate
- Caging and release
- Controlled release
- Specific targeting of container to destination
- Robotics
What are potential applications for containers?
These are applications for which one suspects there may be demand in the outside community
- Drug and gene delivery
- Issues
- Slow down the clearance time in plasma and intracellularly
- Size of pores
- Getting into cell
- Issues
- Directed evolution (compartmentalized selections)
- Chemical synthesis
- Increase effective concentration of reactants
- Using multiplexing for combinatorial synthesis
- Protein folding (chaperone)
- Capture and stabilization of multiprotein complexes
- Marker scavenging
- Cell sorting (gattaca technology)
What are demand-meeting applications for containers?
Can move items from the "potential applications" list down to this list when you can find specific examples (i.e. names of molecules involved) where a demand exists for this application; for many people, this is the only list that matters
How exactly to implement container and lid?
Biotin/streptavinin docking?
Back to brainstorming