Homology Modelling: Difference between revisions

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*[[Modeller|Modeller]]
*[[Modeller|Modeller]]
*iTASSER[https://zhanglab.ccmb.med.umich.edu]
*SWISS-MODEL[https://swissmodel.expasy.org]
[[Category:Protocol]]
After submitting your model query and receiving a structure, keep in mind that the accuracy of the hypothetical model may vary dramatically for given domains. Often times, in addition to accuracy scores, it is beneficial to see a per-residue accuracy which can usually be done through coloring the model by B-factor[https://www.cgl.ucsf.edu/chimera/docs/UsersGuide/tutorials/bfactor.html, ]. Itasser automatically assigns per-residue modeling accuracy scores as the B-factor of its models. This can be visualized easily in the latest edition of PyMol by first opening your model and then selecting "A-->preset-->b factor putty".
[[Category:In silico]]
[[Category:Protein]]
[[Category:Modelling]]

Latest revision as of 14:17, 12 March 2020

After submitting your model query and receiving a structure, keep in mind that the accuracy of the hypothetical model may vary dramatically for given domains. Often times, in addition to accuracy scores, it is beneficial to see a per-residue accuracy which can usually be done through coloring the model by B-factor[3]. Itasser automatically assigns per-residue modeling accuracy scores as the B-factor of its models. This can be visualized easily in the latest edition of PyMol by first opening your model and then selecting "A-->preset-->b factor putty".