Hlavacek

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Research Interests

Modeling of cellular regulatory systems

  • Biomolecular site dynamics
  • Cell signaling in immmunity and cancer
  • Autophagy
  • Computational methods and software tools

Bioinformatics

  • TF binding site prediction

Selected Publications

  • Maienschein-Cline M, Dinner AR, Hlavacek WS, Mu F (2012) Improved predictions of transcription factor binding sites using physicochemical features of DNA. Nucleic Acids Res doi: 10.1093/nar/gks771 PMID 22923524
  • Martin KR, Barua D, Kauffman AL, Westrate LM, Posner RG, Hlavacek WS, MacKeigan JP (2013) Computational model for autophagic vesicle dynamics in single cells. Autophagy 9, 74-92. PMID 23196898
  • Hlavacek WS, Faeder JR, Blinov ML, Posner RG, Hucka M, Fontana W (2006) Rules for modeling signal-transduction systems. Science's STKE 2006, re6. PMID 16849649


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