Haynes Lab:Notebook/James Alling

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Project Description/Abstract

Synthetic Biology seeks to use information biologists have learned about genetic code and its expression to control and create man-made machines for various purposes. This field has specifically been focused in genetic sequence replacements, mutations, and expression. I want to start to apply principle of engineering and synthetic biology with the scientific knowledge of epigenetic functionality of DNA to a useful end.

Presently, I am considering ways to mimic computation at the epigenetic level using histone tail modifications to express or repress effective gene sequences. Also, I'm interested in in vitro assembly of chromatin.

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