Haynes Lab:Notebook/Engineering PC-TFs

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Project Description/Abstract

  • Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically.

Notes

  • Brady Laughlin's Spring/Fall 2012 project in the Haynes Lab at Arizona State University
  • BME 394 Honors Research Project
  • Brady was accepted into the Fulton Undergraduate Research Initiative (FURI) for the Spring 2013 semester.


Recent changes

31 October 2014

       13:50 Haynes Lab:Notebook/Engineering PC-TFs (diff; hist) . .  (-42) . . Cameron Lee Gardner (Talk | contribs) (Notes: )

30 October 2014

+ N    00:55 Haynes Lab:Notebook/Engineering PC-TFs/2014/10/30‎ (2 changes) . . (+966) . . (Page history) [Cameron Lee Gardner‎ (2×)]
+ N    00:55 Haynes Lab:Notebook/Engineering PC-TFs/2014/10/23‎ (2 changes) . . (+966) . . (Page history) [Cameron Lee Gardner‎ (2×)]
+ N    00:55 Haynes Lab:Notebook/Engineering PC-TFs/2014/10/16‎ (2 changes) . . (+966) . . (Page history) [Cameron Lee Gardner‎ (2×)]
+      00:54 Haynes Lab:Notebook/Engineering PC-TFs/2014/10/28‎ (3 changes) . . (+399) . . (Page history) [Cameron Lee Gardner‎ (3×)]


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