Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically.
Brady Laughlin's Spring/Fall 2012 project in the Haynes Lab at Arizona State University
BME 394 Honors Research Project
Brady was accepted into the Fulton Undergraduate Research Initiative (FURI) for the Spring 2013 semester.