Haynes Lab:Notebook/Engineering PC-TFs

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Project Description/Abstract

  • Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically.


  • Brady Laughlin's Spring 2012 project in the Haynes Lab at Arizona State University

Recent changes

18 August 2014

+ N    22:35 Haynes Lab:Notebook/Engineering PC-TFs/2014/08/18‎ (4 changes) . . (+3,084) . . (Page history) [Cameron Lee Gardner‎ (4×)]
+ N    18:48 Haynes Lab:Notebook/Engineering PC-TFs/2014/08/14‎ (2 changes) . . (+1,366) . . (Page history) [Cameron Lee Gardner‎ (2×)]

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