Haynes Lab:Notebook/Engineering PC-TFs
From OpenWetWare
(Difference between revisions)
(→Notes) |
(→Project Description/Abstract) |
||
| Line 14: | Line 14: | ||
|colspan="2"| | |colspan="2"| | ||
==Project Description/Abstract== | ==Project Description/Abstract== | ||
| - | [[Image:engineering_pctfs.jpg|thumb|right|]] | + | [[Image:engineering_pctfs.jpg|10px|thumb|right|]] |
* Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically. | * Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically. | ||
Revision as of 23:40, 15 February 2012
|
| |
Customize your entry pages 
| |
Project Description/Abstract
Notes
| |
|
Recent changes
| |
