Haynes Lab:Notebook/Engineering PC-TFs

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Revision as of 20:03, 26 January 2012

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Project Description/Abstract

  • Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically.


  • Brady Laughlin's Spring 2012 project in the Haynes Lab at Arizona State University

Recent changes

20 April 2015

+      16:31 Haynes Lab:Notebook/Engineering PC-TFs/2015/04/20‎ (10 changes) . . (+401) . . (Page history) [David Tze‎ (10×)]

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