Haynes Lab

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Our group uses synthetic, systems, and quantitative biology to engineer useful gene and protein-based biological devices and to deepen our understanding of molecular cell biology. We operate biological devices primarily in human/ mammalian cells. Accelerating the pace of therapeutic technologies (such as tissue regeneration and customizable protein-based drugs) via modular design is the grand challenge that shapes our research plans.

CURRENT PROJECTS

  • Synthetic chromatin for human cell differentiation - Behzad Damadzadeh
  • Microbial communication with synthetic quorum sensing - Rene Davis
  • Engineering epigenetic transcription factors - Cameron Gardner (FURI)
  • Protein-DNA fusions in living microbes - Ryan Muller (SOLUR)
  • Synthetic chromatin and UV-damage - Brendan Fries (SOLUR)
  • K-12 mammalian cell synthetic biology with Open-PCR and a single-drop fluorimeter - Alfonso Rivera-Passapera and Zazu Moloi (SynBERC)
  • Synthetic chromatin for pancreatic cell development - David Barclay (FURI)

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