Our group uses synthetic, systems, and quantitative biology to engineer useful gene and protein-based biological devices and to deepen our understanding of molecular cell biology. We operate biological devices primarily in human/ mammalian cells. Accelerating the pace of therapeutic technologies (such as tissue regeneration and customizable protein-based drugs) via modular design is the grand challenge that shapes our research plans.
- Synthetic chromatin for cell differentiation - David Barclay (FURI) - pancreas, Jan Simper (FURI) - cardiac
- Editing synthetic genes using CRISPR - René Davis
- Engineering synthetic chromatin transcription factors - Cameron Gardner (FURI)
- Microbial communication with synthetic quorum sensing - René Davis
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