Haynes Lab: Difference between revisions

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CURRENT PROJECTS<br>
CURRENT PROJECTS<br>
* '''Synthetic chromatin for cell differentiation''' - David Barclay (FURI) - pancreas, Jan Simper (FURI) - cardiac
 
* '''Editing synthetic genes using CRISPR''' - René Davis
'''Synthetic chromatin for cell differentiation'''
* David Barclay (FURI, BS) - pancreas, Jan Simper (FURI, BS) - cardiac
* Description: Testing the synthetic chromatin protein/ transcription activator described in Haynes & Silver 2011 to assess its ability to alter the phenotypes of healthy cells, such as pancreas beta cells and iPSC's.
 
'''Editing synthetic genes using CRISPR'''
* René Davis (Biological Design, PhD)
* Description:
 
 
* '''Engineering synthetic chromatin transcription factors''' - Cameron Gardner (FURI)
* '''Engineering synthetic chromatin transcription factors''' - Cameron Gardner (FURI)
* '''Microbial communication with synthetic quorum sensing''' - René Davis, Ryan Muller (SOLUR)
* '''Microbial communication with synthetic quorum sensing''' - René Davis, Ryan Muller (SOLUR)

Revision as of 15:38, 13 November 2014


Our group uses synthetic, systems, and quantitative biology to engineer useful gene and protein-based biological devices and to deepen our understanding of molecular cell biology. We operate biological devices primarily in human/ mammalian cells. Accelerating the pace of therapeutic technologies (such as tissue regeneration and customizable protein-based drugs) via modular design is the grand challenge that shapes our research plans.

CURRENT PROJECTS

Synthetic chromatin for cell differentiation

  • David Barclay (FURI, BS) - pancreas, Jan Simper (FURI, BS) - cardiac
  • Description: Testing the synthetic chromatin protein/ transcription activator described in Haynes & Silver 2011 to assess its ability to alter the phenotypes of healthy cells, such as pancreas beta cells and iPSC's.

Editing synthetic genes using CRISPR

  • René Davis (Biological Design, PhD)
  • Description:


  • Engineering synthetic chromatin transcription factors - Cameron Gardner (FURI)
  • Microbial communication with synthetic quorum sensing - René Davis, Ryan Muller (SOLUR)

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