Harvard:SysBio 204/2014: Difference between revisions
From OpenWetWare
Jump to navigationJump to search
No edit summary |
No edit summary |
||
Line 75: | Line 75: | ||
{{Special:Recentchanges/b=Harvard:SysBio_204/2012&limit=50}} | {{Special:Recentchanges/b=Harvard:SysBio_204/2012&limit=50}} | ||
* Collaboration Policy added to Midterm and Final Page | * Collaboration Policy added to [http://openwetware.org/wiki/Harvard:SysBio_204/2014:Final Midterm and Final Page] (8/27/14) |
Revision as of 12:03, 27 August 2014
Course overview
- A course focusing on the rational design, construction, and applications of nucleic acid and protein-based synthetic molecular and cellular machinery and systems. Students are mentored to produce substantial term projects.
- Intended for graduate students in Systems Biology, Biophysics, Engineering, Biology and related disciplines. No formal prerequisites. Projects are tailored to each student's strengths and interests.
- Website: http://sb204.net
- Poster
Midterm and Final
- There will be two midterms and one final project for this class
- Policy: strict submission deadline, we encourage you to submit your work the night before
- Midterm #1 due: October 2nd at noon
- Midterm #2 due: October 22nd
- Final project due: November 28
- Method of submission: email TA your slides and presentations
- Midterm and Final Projects (2013, to be updated)
Logistics
- Instructors: George Church, William Shih, Pamela Silver, Peng Yin
- Teaching Fellow: Evan Daugharthy
- Meeting time: 2:30 - 4:00 PM, Mon/Wed, Fall 2014
- Location: Room 521, Wyss Institute, 3 Blackfan circle, Boston, 02115
- First class on Wednesday Sep 3rd.
- Location: CLSB521
- No exams
- Prerequisites: none
- Grading
- 20% Participation
- 40% Midterm projects
- 40% Final project
- Harvard course site
Background Info and previous class projects
- BPH242r 2008-2009 http://openwetware.org/wiki/Biophysics_242r/2009 (Synthetic Biology)
- BPH242r 2010-2011 http://openwetware.org/wiki/Harvard:Biophysics_242r/2011 (Biologically Inspired Molecular Engineering)
- SB204 2011-2012 http://openwetware.org/wiki/Harvard:SysBio_204/2011
- SB204 2012-2013 http://openwetware.org/wiki/Harvard:SysBio_204/2012
- SB204 2013-2014 http://openwetware.org/wiki/Harvard:SysBio_204/2013
Example topics for final design project
- miRNA pattern recognition in eukaryotic cells
- Directed evolution of chemical sensors
- Nano-breadboards for probing electron transport in proteins
- Altered genetic codes and amino acid alphabets
- Modification of proteins for function in harsh environments
- Automatable assembly of large synthetic genes and circuits
- Synthetic biology of stem cells and epigenetic reprogramming pathways
- Structural re-engineering of adenoviruses
- Artificial chemotactic swimmers
- Nonequilibrium networks of nano-machines mimicking dynamic instability in the cytoskeleton
- Recombinase-based multi-state memory in bacteria
- Exosome manufacturing
- Self-assembled solar energy harvester based on bio-inorganic nano-antennae for uv-vis
- Systematic debugging of DNA labeling chemistries by atomic-resolution TEM imaging of DNA origami
- Transcriptional activation and repression through rational molecular design
- Tissue engineering scaffold nano-materials
- Programmable multistep chemical synthesis by templating on catalytic nanostructures
- Ultra-sensitive signal processing for synthetic biology
- Antibody 2.0
- Synthetic nanostructure - virus conjugates
- Replication of information in synthetic crystals
- Cheap large-scale production of protein or DNA-based materials
- Etc. Etc. Etc.
Recent changes
List of abbreviations:
- N
- This edit created a new page (also see list of new pages)
- m
- This is a minor edit
- b
- This edit was performed by a bot
- (±123)
- The page size changed by this number of bytes
24 April 2024
|
17:49 | Hu 2 changes history +28 [Hugangqing (2×)] | |||
|
17:49 (cur | prev) +18 Hugangqing talk contribs | ||||
|
17:48 (cur | prev) +10 Hugangqing talk contribs |
|
08:14 | "Pick and Place" Assembly of Parts Using PDMS - Amy Lim, Rylie Costello 6 changes history +394 [Rcostello (6×)] | |||
|
08:14 (cur | prev) +1 Rcostello talk contribs (→"Pick and Place" Methodology) | ||||
|
08:13 (cur | prev) −14 Rcostello talk contribs (→"Pick and Place" Methodology) | ||||
|
08:12 (cur | prev) −1 Rcostello talk contribs (→"Pick and Place" Methodology) | ||||
|
08:12 (cur | prev) −1 Rcostello talk contribs (→"Pick and Place" Methodology) | ||||
|
08:12 (cur | prev) +110 Rcostello talk contribs (→References) | ||||
|
08:11 (cur | prev) +299 Rcostello talk contribs (→"Pick and Place" Methodology) |
08:02 | Upload log Rcostello talk contribs uploaded File:Pick and Place.mp4 |
|
06:23 | WAKNA:Basics 2 changes history −229 [Berthold Drexler (2×)] | |||
|
06:23 (cur | prev) +192 Berthold Drexler talk contribs (→Hier finden Sie Literatur für Einsteiger:innen in das Gebiet der Neuroanästhesie) | ||||
|
06:21 (cur | prev) −421 Berthold Drexler talk contribs (→Sonstige) |
23 April 2024
|
15:33 | "Pick and Place" Assembly of Parts Using PDMS - Amy Lim, Rylie Costello 6 changes history +837 [Rcostello (6×)] | |||
|
15:33 (cur | prev) +1 Rcostello talk contribs (→"Pick and Place" for Microfluidics) | ||||
|
15:33 (cur | prev) +203 Rcostello talk contribs (→References) | ||||
|
15:31 (cur | prev) −2 Rcostello talk contribs (→"Pick and Place" for Microfluidics) | ||||
|
15:29 (cur | prev) −474 Rcostello talk contribs (→References) | ||||
|
15:29 (cur | prev) +845 Rcostello talk contribs (→MEMS Devices) | ||||
|
15:14 (cur | prev) +264 Rcostello talk contribs (→"Pick and Place" for Microfluidics) |
|
11:58 | BioMicroCenter:People 2 changes history +30 [Lttran (2×)] | |||
|
11:58 (cur | prev) −4 Lttran talk contribs (→BioMicro Center Staff) | ||||
|
11:49 (cur | prev) +34 Lttran talk contribs (→BioMicro Center Staff) |
11:46 | Upload log Lttran talk contribs uploaded File:SKR BMC.jpg |
22 April 2024
|
19:28 | "Pick and Place" Assembly of Parts Using PDMS - Amy Lim, Rylie Costello 4 changes history +1 [Rcostello (4×)] | |||
|
19:28 (cur | prev) −2 Rcostello talk contribs (→Nanowires) | ||||
|
19:26 (cur | prev) 0 Rcostello talk contribs (→Biology-Inspired Solution) | ||||
|
15:03 (cur | prev) +2 Rcostello talk contribs (→At the Microscale) | ||||
|
15:02 (cur | prev) +1 Rcostello talk contribs (→Overview) |
09:24 | CHEM-ENG590E:Wiki Textbook diffhist +16 Rcostello talk contribs (→Chapter 15 - Other Topics) |
09:24 | Move log Rcostello talk contribs moved page "Pick and Place" Assembly of Parts Using PDMS - Amy Lim to "Pick and Place" Assembly of Parts Using PDMS - Amy Lim, Rylie Costello |
08:59 | "Pick and Place" Assembly of Parts Using PDMS - Amy Lim diffhist −2,792 Rcostello talk contribs (→"Pick and Place" for Microfluidics) |
21 April 2024
22:55 | Lee:JC diffhist +24 Wooin Lee talk contribs (→2024) |
17:42 | Ernesto-Perez-Rueda:Publications diffhist +55 Ernesto Perez-Rueda talk contribs |
19 April 2024
|
21:58 | Hu 2 changes history +58 [Hugangqing (2×)] | |||
|
21:58 (cur | prev) −8 Hugangqing talk contribs | ||||
|
21:58 (cur | prev) +66 Hugangqing talk contribs |
18 April 2024
- Collaboration Policy added to Midterm and Final Page (8/27/14)