Frankel:Force Spectroscopy

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
Line 9: Line 9:
<div>
<div>
-
|  align="justify" width=400px style="border: 2px solid #000033; background-color:#FFFFFF; padding:1em;" class="plainlinks" valign="top"|
+
|  align="center" width=400px style="border: 2px solid #000033; background-color:#FFFFFF; padding:1em;" class="plainlinks" valign="top"|
-
'''<font color=#FFFFFF font size=8>HIV-gp160</font>'''
+
'''<font color=#000000 font size=3>Picking up and unfolding a single protein</font>'''
[[Image:Spectroscopy_complete.jpg|350px]]
[[Image:Spectroscopy_complete.jpg|350px]]

Revision as of 11:33, 8 January 2013

Danbanner-bio-machines.jpg



'______ 'Force Spectroscopy


Assembly

Nano-mechanics of HIV GP160


GP160mica


Typical sawtooth unfolding pattern of a single molecule of the HIV virion protein GP160. Unfolding forces can be extracted from the sawtooth pattern by applying the worm like chain model.





Unfolding the ECM protein fibronectin





Sawtooth pattern on the retraction force curve indicating the unfolding of fibronectin. The average rupture force distribution of the protein on mica surface was 85.1 ± 2.7 pN.

Personal tools