Error Detection & Correction in Replicating Machines: Difference between revisions
Line 10: | Line 10: | ||
*[[Jason Kelly]] | *[[Jason Kelly]] | ||
*[[Jeff Gritton]] | *[[Jeff Gritton]] | ||
*[[Austin Che]] | |||
===Next Meeting=== | ===Next Meeting=== |
Revision as of 14:15, 13 July 2005
Replication with Error Working Group
Introduction
Biological systems are replicating machines that make (a small number of) errors during the machine replication process. From a practical engineering standpoint, we need to understand how to design biological systems that perform as expected. We can imagine that a future biological engineer might be called upon to design an 8-bit counter that has a p(working) > 0.99 upto 256 doubling events. Or, we can imagine needing to design a metabolic pathway that has a p(failure) > 0.99 after 3000 doubling events. And so on. In other words, the evolutionary stability, or lack thereof, for our engineering biological systems should become part of the initial system specification, and our designs should be able to meet these specifications. From a scientific perspective, we suspect that learning how to solve questions of error detection and correction in replicating machines will lead to a better understanding of biological evolution.
Interested Folks
Next Meeting
- 4-6p on Tuesday July 26 confirmed Room 68-574
- PM on Tuesday July 26 suggested
- DE, TK both OK
- GJS. Anytime starting at 11a.
- JG. Anytime after 2p.
- JK OK anytime
Suggested Folks (not yet contacted/signed up)
- Norm Margolus
- Jonathan Rees
Background Reading & External Links
- Theory of Self-Reproducing Automata, John von Neumann
- Drew has a copy of this if anybody wants to read it.
- Daniel Weise @ UW CS