Endy:Research - Revision history

Endy: /* Genetic Data Storage */

2012-05-21T22:37:56Z

Genetic Data Storage

←Older revision		Revision as of 22:37, 21 May 2012
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	===Genetic Data Storage===		===Genetic Data Storage===
-	We are focused on the development of engineered DNA systems that are capable of data storage inside living cells. Our [http://blogs.scientificamerican.com/observations/2012/05/21/scientists-engineer-rewriteable-digital-data-storage-in-the-dna-of-living-bacteria/ recent work] has focused on non-volatile recombinase addressable data (RAD) storage engineered from serine recombinases to target reversibly-invertible chromosomal data registers. We are interested in scaling genetically-encoded data systems from from a few bits to a few bytes.	+	We are focused on the development of engineered DNA systems that are capable of data storage inside living cells. Our [http://blogs.scientificamerican.com/observations/2012/05/21/scientists-engineer-rewriteable-digital-data-storage-in-the-dna-of-living-bacteria/ recent work] has focused on non-volatile recombinase addressable data (RAD) storage engineered from serine recombinases that target reversibly-invertible chromosomal data registers. We are interested in scaling genetically-encoded data systems from from a few bits to a few bytes.

	===Engineering Biology===		===Engineering Biology===

Endy: /* Genetic Data Storage */

2012-05-21T22:37:35Z

Genetic Data Storage

←Older revision		Revision as of 22:37, 21 May 2012
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	===Genetic Data Storage===		===Genetic Data Storage===
-	We are focused on the development of engineered DNA systems that are capable of data storage inside living cells. Our [http://blogs.scientificamerican.com/observations/2012/05/21/scientists-engineer-rewriteable-digital-data-storage-in-the-dna-of-living-bacteria/ recent work] has focused on non-volatile recombinase addressable data (RAD) storage ~~made by using~~ serine recombinases to target reversibly-invertible chromosomal data registers. We are interested in scaling genetically-encoded data systems from from a few bits to a few bytes.	+	We are focused on the development of engineered DNA systems that are capable of data storage inside living cells. Our [http://blogs.scientificamerican.com/observations/2012/05/21/scientists-engineer-rewriteable-digital-data-storage-in-the-dna-of-living-bacteria/ recent work] has focused on non-volatile recombinase addressable data (RAD) storage engineered from serine recombinases to target reversibly-invertible chromosomal data registers. We are interested in scaling genetically-encoded data systems from from a few bits to a few bytes.

	===Engineering Biology===		===Engineering Biology===

Endy: /* Engineering Biology */

2012-05-21T21:42:43Z

Engineering Biology

←Older revision		Revision as of 21:42, 21 May 2012
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	===Engineering Biology===		===Engineering Biology===
-	Our overall long term goal is to help make biology easy to engineer, an area of research sometimes known as synthetic biology. ~~We are particularly interested in adapting~~ ideas from metrology ~~in order to better coordinate~~ the distributed measurement and representation of in vivo molecular activities. We ~~are~~ also ~~particularly interested in implementing~~ genetic layout architectures that help to establish reliably reusable standard biological ~~across a functional~~ abstraction ~~hierarchy~~.	+	Our overall long term goal is to help make biology easy to engineer, an area of research sometimes known as synthetic biology. In particular, we adapt ideas from metrology that help enable the distributed measurement and representation of in vivo molecular activities. We also develop genetic layout architectures that help establish reliably reusable standard biological parts supporting abstraction of biological functions.

	===Research Background & Context, Additional Materials===		===Research Background & Context, Additional Materials===
	The many and diverse dissertations from past students in the lab, their peer-reviewed published articles, and our written perspectives and other published projects are all [[Endy:Reprints \| freely available online]]. We hope that students who are interested in exploring and taking forward their own research projects in the lab will be informed and inspired by the curiosity and independence of past student's work. We hope that others who are interested in understanding, contributing to, or constructively criticizing the lab's work make full use of our published record.		The many and diverse dissertations from past students in the lab, their peer-reviewed published articles, and our written perspectives and other published projects are all [[Endy:Reprints \| freely available online]]. We hope that students who are interested in exploring and taking forward their own research projects in the lab will be informed and inspired by the curiosity and independence of past student's work. We hope that others who are interested in understanding, contributing to, or constructively criticizing the lab's work make full use of our published record.

Endy: /* Synthetic Biology */

2012-05-21T21:39:43Z

Synthetic Biology

←Older revision		Revision as of 21:39, 21 May 2012
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	We are focused on the development of engineered DNA systems that are capable of data storage inside living cells. Our [http://blogs.scientificamerican.com/observations/2012/05/21/scientists-engineer-rewriteable-digital-data-storage-in-the-dna-of-living-bacteria/ recent work] has focused on non-volatile recombinase addressable data (RAD) storage made by using serine recombinases to target reversibly-invertible chromosomal data registers. We are interested in scaling genetically-encoded data systems from from a few bits to a few bytes.		We are focused on the development of engineered DNA systems that are capable of data storage inside living cells. Our [http://blogs.scientificamerican.com/observations/2012/05/21/scientists-engineer-rewriteable-digital-data-storage-in-the-dna-of-living-bacteria/ recent work] has focused on non-volatile recombinase addressable data (RAD) storage made by using serine recombinases to target reversibly-invertible chromosomal data registers. We are interested in scaling genetically-encoded data systems from from a few bits to a few bytes.

-	===~~Synthetic~~ Biology===	+	===Engineering Biology===
-	Our overall long term goal is to help make biology easy to engineer, an area of research known as synthetic biology.	+	Our overall long term goal is to help make biology easy to engineer, an area of research sometimes known as synthetic biology. We are particularly interested in adapting ideas from metrology in order to better coordinate the distributed measurement and representation of in vivo molecular activities. We are also particularly interested in implementing genetic layout architectures that help to establish reliably reusable standard biological across a functional abstraction hierarchy.

	===Research Background & Context, Additional Materials===		===Research Background & Context, Additional Materials===
	The many and diverse dissertations from past students in the lab, their peer-reviewed published articles, and our written perspectives and other published projects are all [[Endy:Reprints \| freely available online]]. We hope that students who are interested in exploring and taking forward their own research projects in the lab will be informed and inspired by the curiosity and independence of past student's work. We hope that others who are interested in understanding, contributing to, or constructively criticizing the lab's work make full use of our published record.		The many and diverse dissertations from past students in the lab, their peer-reviewed published articles, and our written perspectives and other published projects are all [[Endy:Reprints \| freely available online]]. We hope that students who are interested in exploring and taking forward their own research projects in the lab will be informed and inspired by the curiosity and independence of past student's work. We hope that others who are interested in understanding, contributing to, or constructively criticizing the lab's work make full use of our published record.

Endy: /* Genetic Data Storage */

2012-05-21T21:36:42Z

Genetic Data Storage

←Older revision		Revision as of 21:36, 21 May 2012
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	===Genetic Data Storage===		===Genetic Data Storage===
-	We are focused on the development of engineered DNA systems that are capable of data storage inside living cells. Our ~~work to~~-~~date~~ has focused on non-volatile recombinase addressable data (RAD) storage made by using serine recombinases to target reversibly-invertible chromosomal data registers. We are interested in scaling genetically-encoded data systems from from a few bits to a few bytes.	+	We are focused on the development of engineered DNA systems that are capable of data storage inside living cells. Our [http://blogs.scientificamerican.com/observations/2012/05/21/scientists-engineer-rewriteable-digital-data-storage-in-the-dna-of-living-bacteria/ recent work] has focused on non-volatile recombinase addressable data (RAD) storage made by using serine recombinases to target reversibly-invertible chromosomal data registers. We are interested in scaling genetically-encoded data systems from from a few bits to a few bytes.

	===Synthetic Biology===		===Synthetic Biology===

Endy: /* Genetic Data Storage */

2012-05-21T21:31:24Z

Genetic Data Storage

←Older revision		Revision as of 21:31, 21 May 2012
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	===Genetic Data Storage===		===Genetic Data Storage===
-	We are focused on the development of engineered DNA systems that are capable of data storage inside living ~~systems~~. Our work to-date has focused on non-volatile recombinase addressable data (RAD) storage made by using serine recombinases to target reversibly-invertible chromosomal data registers. We are interested in scaling genetically-encoded data systems from from a few bits to a few bytes.	+	We are focused on the development of engineered DNA systems that are capable of data storage inside living cells. Our work to-date has focused on non-volatile recombinase addressable data (RAD) storage made by using serine recombinases to target reversibly-invertible chromosomal data registers. We are interested in scaling genetically-encoded data systems from from a few bits to a few bytes.

	===Synthetic Biology===		===Synthetic Biology===

Endy: /* Notebooks */

2012-05-21T21:17:20Z

Notebooks

←Older revision		Revision as of 21:17, 21 May 2012
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	===Research Background & Context, Additional Materials===		===Research Background & Context, Additional Materials===
	The many and diverse dissertations from past students in the lab, their peer-reviewed published articles, and our written perspectives and other published projects are all [[Endy:Reprints \| freely available online]]. We hope that students who are interested in exploring and taking forward their own research projects in the lab will be informed and inspired by the curiosity and independence of past student's work. We hope that others who are interested in understanding, contributing to, or constructively criticizing the lab's work make full use of our published record.		The many and diverse dissertations from past students in the lab, their peer-reviewed published articles, and our written perspectives and other published projects are all [[Endy:Reprints \| freely available online]]. We hope that students who are interested in exploring and taking forward their own research projects in the lab will be informed and inspired by the curiosity and independence of past student's work. We hope that others who are interested in understanding, contributing to, or constructively criticizing the lab's work make full use of our published record.
-
-	~~===Notebooks===~~
-	*[[Endy:Notebook \| Lab Meta-Notebook]]

Endy: /* Genetic Memory */

2012-05-21T21:16:44Z

Genetic Memory

←Older revision		Revision as of 21:16, 21 May 2012
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-	===Genetic ~~Memory~~===	+	===Genetic Data Storage===
-	~~The immediate goal of our research is to enable~~ the ~~engineering~~ of ~~genetically encoded memory~~ systems~~. Modest amounts~~ of ~~programmable memory, if implemented within~~ living ~~organisms, would have profound impacts~~ on ~~the study and treatment of diseases and would broadly enable~~ non-~~medical applications of biotechnology~~. We are interested in ~~both the basic and applied aspects of the problem,~~ from ~~considering how to best store information inside cells~~ to ~~practical applications~~.	+	We are focused on the development of engineered DNA systems that are capable of data storage inside living systems. Our work to-date has focused on non-volatile recombinase addressable data (RAD) storage made by using serine recombinases to target reversibly-invertible chromosomal data registers. We are interested in scaling genetically-encoded data systems from from a few bits to a few bytes.

	===Synthetic Biology===		===Synthetic Biology===

Endy: /* Research Background & Context, Additional Materials */

2009-07-22T19:01:08Z

Research Background & Context, Additional Materials

←Older revision		Revision as of 19:01, 22 July 2009
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	===Research Background & Context, Additional Materials===		===Research Background & Context, Additional Materials===
-	The many and diverse dissertations from past students in the lab, their peer-reviewed published articles, and our written perspectives and other published projects are all [[Endy:Reprints \| freely available online]]. We hope that students who ~~might be~~ interested in ~~defining~~ and taking forward their own research projects in the lab ~~might~~ be ~~motivated or~~ inspired by the curiosity and independence of past student ~~projects~~. We hope that others who are interested in understanding, contributing to, or constructively criticizing ~~our~~ work make full use of our published record.	+	The many and diverse dissertations from past students in the lab, their peer-reviewed published articles, and our written perspectives and other published projects are all [[Endy:Reprints \| freely available online]]. We hope that students who are interested in exploring and taking forward their own research projects in the lab will be informed and inspired by the curiosity and independence of past student's work. We hope that others who are interested in understanding, contributing to, or constructively criticizing the lab's work make full use of our published record.

	===Notebooks===		===Notebooks===
	*[[Endy:Notebook \| Lab Meta-Notebook]]		*[[Endy:Notebook \| Lab Meta-Notebook]]

Endy: /* Research Background & Context, Additional Materials */

2009-07-22T18:59:29Z

Research Background & Context, Additional Materials

←Older revision		Revision as of 18:59, 22 July 2009
Line 10:		Line 10:

	===Research Background & Context, Additional Materials===		===Research Background & Context, Additional Materials===
-	The many and diverse dissertations from past students in the lab, their peer-reviewed published articles, and our written perspectives and other published projects are all [[freely available online]]. We hope that students who might be interested in defining and taking forward their own research projects in the lab might be motivated or inspired by the curiosity and independence of past student projects. We hope that others who are interested in understanding, contributing to, or constructively criticizing our work make full use of our published record.	+	The many and diverse dissertations from past students in the lab, their peer-reviewed published articles, and our written perspectives and other published projects are all [[Endy:Reprints \| freely available online]]. We hope that students who might be interested in defining and taking forward their own research projects in the lab might be motivated or inspired by the curiosity and independence of past student projects. We hope that others who are interested in understanding, contributing to, or constructively criticizing our work make full use of our published record.

	===Notebooks===		===Notebooks===
	*[[Endy:Notebook \| Lab Meta-Notebook]]		*[[Endy:Notebook \| Lab Meta-Notebook]]