Endy:Chassis engineering/VM2.0: Difference between revisions
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==Species== | ==Model== | ||
Continuous differential equation model. | |||
===Species=== | |||
#T7 RNAP | #T7 RNAP | ||
#Repressor | #Repressor |
Revision as of 14:50, 7 March 2007
VM2.0 design considerations
- Stability
- Noise
- Response time
- Self-booting/controlled
- Ability to turn on or off
- Tunable
- Pros and cons of DNA copy number, promoter strength, repressor affinities etc.
- Efficient
- Minimizing levels of repressor needed
- Minimizing consumption of small molecules
What are the metrics for each of the design considerations?
Model
Continuous differential equation model.
Species
- T7 RNAP
- Repressor
- Ribosomes
- Repressible T7 promoter
- T7RNAP-promoter complex
- Repressor-promoter complex
- T7 RNAP mRNA
- Repressor mRNA
- Elongating T7 RNAP
- Elongating Ribosomes
- etc.