Drummond:Publications

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Research

1. Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast. Geiler-Samerotte KA, Dion MF, Budnik BA, Wang SM, Hartl DL, Drummond DA. Proc Natl Acad Sci U S A. (in press, 2010)
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2. Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution. Drummond DA, Wilke CO. Cell. 2008 Jul 25;134(2):341-52. Faculty of 1000 rated
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3. Contact density affects protein evolutionary rate from bacteria to animals. Zhou T, Drummond DA, Wilke CO. J Mol Evol. 2008 Apr;66(4):395-404. Epub 2008 Apr 1.
4. A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments. Li Y, Drummond DA, Sawayama AM, Snow CD, Bloom JD, Arnold FH. Nat Biotechnol. 2007 Sep;25(9):1051-6. Epub 2007 Aug 26. Erratum in: Nat Biotechnol. 2007 Dec;25(12):1488. Faculty of 1000 rated
5. Structural determinants of the rate of protein evolution in yeast. Bloom JD, Drummond DA, Arnold FH, Wilke CO. Mol Biol Evol. 2006 Sep;23(9):1751-61. Epub 2006 Jun 16.
6. Population genetics of translational robustness. Wilke CO, Drummond DA. Genetics. 2006 May;173(1):473-81. Epub 2006 Feb 19.
7. A single determinant dominates the rate of yeast protein evolution. Drummond DA, Raval A, Wilke CO. Mol Biol Evol. 2006 Feb;23(2):327-37. Epub 2005 Oct 19. Faculty of 1000 rated
8. Why highly expressed proteins evolve slowly. Drummond DA, Bloom JD, Adami C, Wilke CO, Arnold FH. Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14338-43. Epub 2005 Sep 21. Faculty of 1000 rated
9. Predicting the tolerance of proteins to random amino acid substitution. Wilke CO, Bloom JD, Drummond DA, Raval A. Biophys J. 2005 Dec;89(6):3714-20. Epub 2005 Sep 8.
10. Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteins. Drummond DA, Iverson BL, Georgiou G, Arnold FH. J Mol Biol. 2005 Jul 22;350(4):806-16. Faculty of 1000 rated
11. On the conservative nature of intragenic recombination. Drummond DA, Silberg JJ, Meyer MM, Wilke CO, Arnold FH. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5380-5. Epub 2005 Apr 4.
12. Thermodynamic prediction of protein neutrality. Bloom JD, Silberg JJ, Wilke CO, Drummond DA, Adami C, Arnold FH. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):606-11. Epub 2005 Jan 11. Faculty of 1000 rated

Reviews

1. Signatures of protein biophysics in coding sequence evolution. Wilke CO, Drummond DA. Curr Opin Struct Biol. 2010 Jun;20(3):385-9. Epub 2010 Apr 13. Review.
2. Protein evolution: innovative chaps. Drummond DA. Curr Biol. 2009 Sep 15;19(17):R740-2.
3. The evolutionary consequences of erroneous protein synthesis. Drummond DA, Wilke CO. Nat Rev Genet. 2009 Oct;10(10):715-24. Review.