Dr.HeidiM.Mansour

Contact Info

Dr. Heidi M. Mansour, Ph.D., R.Ph. Assistant Professor of Pharmaceutics & Drug Delivery, Faculty Associate in the UK Center of Membrane Sciences, UK College of Pharmacy Dept of Pharmaceutical Sciences-Drug Development 789 South Limestone Street Office 331 Biological Pharmaceutical Complex Lexington, Kentucky 40536-0596

Telephone: (859) 257-1571; Email: heidi.mansour@uky.edu

Websites

1. http://pharmacy.mc.uky.edu/faculty/HeidiMansour.php

2. http://myprofile.cos.com/surfchemlungmed

Editorial Advisory Board Member (EAB) & Expert Committees

1. Pharmaceutical Technology North America[1]

2. Journal of Nanomedicine & Nanotechnology [2]

3. Journal of Nanotechnology & Biotherapeutic Discovery [3]

4. Recent Patents on Nanomedicine [4]

5. Recent Patents on Drug Delivery & Formulation [5]

6. Medicinal Chemistry: Current Research [6]

7. Journal of Pharmaceutical Technology & Drug Research (United Kingdom) [7]

8. United States Pharmacopeia Delegate [8]

9. NIH/NICHD U.S. Pediatric Formulations Initiative (PFI) New Drug Delivery Systems (NDDS) Working Group

Book Proposal Publisher Reviewer

1.Springer Publisher

2.Marcel-Dekkar Publisher

3.Elsevier Publisher

4.Wiley-Interscience Publisher

5.Pharmaceutical Press-The Royal Pharmaceutical Society of Great Britain

Honors & Awards

• 2010, Mercer School of Pharmacy Dept of Pharmaceutical Sciences, Pharmabeat 2010 Researcher of the Issue, Mercer University
• 2010, Scholarship of Teaching & Learning Certificate (STLC) Award, UK College of Pharmacy, University of Kentucky
• 2007, NIH Regional Training Award Scholar, National Institutes of Health (NIH)/UNC-Chapel Hill
• 2007-2008, Post Doctoral Fellow Award in Pharmaceutics, PhRMA Foundation
• 2007-2008, Post Doctoral Scholars Award for Research Excellence, Office of the Vice Chancellor, University of North Carolina at Chapel Hill
• 2007, Post Doctoral Fellow Award in Research Excellence, American Association of Pharmaceutical Scientists (AAPS)
• 2001, Walter F. Enz Award in Research Excellence in the Pharmaceutical Sciences, Pharmacia Upjohn Global Pharmaceutical Sciences
• 2000-2002, PhRMA Advanced Predoctoral Fellow Award in Pharmaceutics, Pharmaceutical Researchers & Manufacturers of America (PhRMA) Foundation
• 1999-2001, AFPE Predoctoral Fellow Award, American Foundation for Pharmaceutical Education (AFPE)
• 1996, Merck Award in Excellence in Pharmacy, Merck
• 1996, Distinction and Honors in Pharmacy, School of Pharmacy, University of Wisconsin-Madison
• 1994, Academic Excellence Award, Rho Chi Pharmaceutical Honor Society
• 1993, Sophomore Honors Award, College of Letters and Science, University of Wisconsin-Madison
• 1992, Chemistry Enrichment Award, Department of Chemistry, University of Wisconsin-Madison
• 1991-1995, Wisconsin Academic Excellence Award Scholar, Wisconsin Governor & Wisconsin State Legislature
• 1991, US Presidential Academic Fitness Award Scholar, President of the United States & the United States of America Congress
• 1991, Elected Member, Phi Eta Sigma National Honor Society
• 1991, Elected Member, Phi Kappa Phi National Honor Society
• 1991, Elected Member, Golden Key International Honor Society

Invited Speaker (2005-Present)

1.Yale University, Department of Biomedical Engineering, New Haven, CT.

2.Harvard University, Division of Engineering and Applied Sciences, Cambridge, MA.

3.UNC-Chapel Hill, Chapel Hill, NC.

4.10th Annual Liposome Research Days & 1st UNC Drug Conference, Chapel Hill, NC.

5.PEPSIG, UK COP & UK Engineering, Lexington, KY.

6.International Society of Pharmaceutical Engineers (ISPE), Lexington, KY.

7.UK College of Medicine-Pulmonary Medicine Division/Pediatric Research Group Seminar.

8.UK College of Engineering-NSF REU Faculty Panel Speaker, Lexington, KY.

9.UK Lung Biology Group & UK Pulmonary Medicine Research Conference Seminar,College of Medicine-Pulmonary Medicine Division, Lexington, KY.

10.UK Center of Membrane Sciences Faculty Associates Research Symposium, Lexington, KY.

11.American Oil Chemist's Society (AOCS) Annual Meeting & Exhibition, Phoenix, AZ. Symposium on Phospholipids:"Lipids in Nanotechnology II". Speaker Presentation Title: “Designed Phospholipid Self-Assemblies in Drug Delivery and Nanomedicine”.

12.UK Dept of Biomedical Engineering Seminar Series, Lexington,KY. Seminar Presentation Title: "Advances in Sustained-Release Injectable Depot Drug Delivery and Controlled Release Pulmonary Inhalation Aerosol Drug Delivery"

13.International Society of Pharmaceutical Engineers(ISPE), Lexington, KY. Seminar Presentation Title: "Targeted Pulmonary Dry Powder Inhalation Aerosols: Pulmonary Infection Drug Delivery & Non-Invasive Needle-Free Pulmonary Vaccines”.

14.American Oil Chemist's Society (AOCS) Annual Meeting & Exhibition, Cincinnati, OH. Symposium on “Phospholipids in Pharma and Cosmetics Applications”. Speaker Presentation Title: "Phospholipid Nanopharmaceuticals in Advanced Drug Delivery".

15.International Workshop on Physical Characterization of Pharmaceutical Solids (IWPCPS-13). Indianapolis, IN. Symposium on “Solid-State Transformation During Formulations and Processing”. Speaker Presentation: "Water Vapor-Solid Interactions and Effects on Solid-State Phase Transitions in Engineered Microparticulate/Nanoparticulate Pharmaceutical Powders".

16. International Workshop on Physical Characterization of Pharmaceutical Solids (IWPCPS-13). Indianapolis, IN. Symposium on “Imaging of Drugs and Dosage Forms to Better Understand Dissolution”. Speaker Presentation: "Imaging Techniques for Designed Microparticulate/Nanoparticulate Pharmaceutical Powders".

17. "Hanging with Zwisch" Research Colloquium, UK College of Medicine-Dept of Pulmonary & Surgery. Lexington, KY. Invited Speaker. Presentation Title : "Advances in Targeted Lung Delivery as Inhaled Multifunctional Microparticles & Nanoparticles for Pulmonary Disease Treatment and Prevention”.

18. American Chemical Society (ACS) 242nd Annual Meeting & Exhibition, Division of Colloid & Surface Chemistry-Symposium on “Nanomedicine: Colloids & Surface Science”. Denver, CO. Symposium Session Presider & Invited Symposium Speaker. Presentation Title: "Rational Design, Development, and Optimization of Nanopharmaceuticals for Targeted Drug Delivery in Nanomedicine: An Interfacial and Colloidal Science Approach”.

19. 4th Annual Nanotechnology & Nanomedicine Symposium, Louisville, KY. Invited Speaker. Presentation Title: "Advanced Spray-Dried Vancomycin Hydrochloride and Clarithromycin Lipospheres for Targeted Pulmonary Inhalation Aerosol Delivery."

20. Pfizer, Inc., Worldwide Research & Development, Global Headquarters, Groton, CT. Invited Speaker. Presentation Title: "Engineering Particles by Advanced Spray Drying for Drug Delivery."

21. International Conference & Exhibition on Nanotechnology & Nanomedicine. Invited Speaker. Presentation Title: "Advances in Targeted Lung Nanomedicine as Inhalable Multifunctional Microparticles & Nanoparticles for Pulmonary Disease Treatment and Prevention."

22. Buchi Short-Course on Spray Drying, Buchi U.S. Headquarters. Invited Speaker. Presentation Title: "Engineering Particles by Advanced Organic Solution Spray Drying for Nanopharmaceuticals and Targeted Pulmonary Inhalation Aerosol Delivery."

23. 1st International Symposium on Nanomedicine in Drug Delivery and Cancer Diagnosis. Session Chair Presider & Invited Symposium Speaker. Presentation Title: "Advances in Targeted Lung Nanomedicine as Inhalable Multifunctional Microparticles & Nanoparticles for Pulmonary Disease Treatment and Prevention."

24. 2nd International Symposium on Surface Science: Adhesion Aspects in the Pharmaceutical Sciences. Session Chair Presider & Invited Speaker.

Journal Publications *Corresponding Author*

1. Mansour H., Wang D.-S., Chen C.-S., and Zografi G. Comparison of Bilayer and Monolayer Properties of Phospholipid Systems Containing Dipalmitoylphosphatidylglycerol and Dipalmitoylphosphatidylinositol. Langmuir (2001) 17 (21) October 16: 6622-6632. (Impact Factor: 4.268)[9]

2. *Mansour, H.M.* and Zografi G. The Relationship Between Water Vapor Absorption and Desorption by Phospholipids and Bilayer Phase Transitions. Journal of Pharmaceutical Sciences (2007) 96 (2) February: 377-396. (Impact Factor: 3.031)[10]

3. *Mansour, H.M.* and Zografi G. Relationships Between Equilibrium Spreading Pressure and Phase Equilibria of Phospholipid Bilayers and Monolayers at the Air-Water Interface. Langmuir (2007) 23 (7) March 27: 3809-3819. (Impact Factor: 4.268)[11]

4. *Mansour H.M.*, Damodaran S., and Zografi G. Characterization of the In Situ Structural and Interfacial Properties of the Cationic Hydrophobic Heteropolypeptide, KL4, in Lung Surfactant Bilayer and Monolayer Models at the Air-Water Interface: Implications for Pulmonary Surfactant Delivery. Molecular Pharmaceutics (2008) 5 (5) October 6: 681-695. (Impact Factor: 5.408)[12]

5. Hickey, A.J., Mansour, H.M., et al. Physical Characterization of Component Particles Included in Dry Powder Inhalers: I. Strategy Review and Static Characteristics. Journal of Pharmaceutical Sciences: Special Issue David Grant Dedicated Issue (2007) 96 (5) May: 1282-1301. (Impact Factor: 3.031)[13]

6. Hickey, A.J., Mansour, H.M., et al. Physical Characterization of Component Particles Included in Dry Powder Inhalers: II. Dynamic Characteristics. Journal of Pharmaceutical Sciences: Special Issue David Grant Dedicated Issue (2007) 96 (5) May: 1302-1319. (Impact Factor: 3.031)[14]

7. *Mansour, H.M.* and Hickey, A.J. Raman Characterization and Chemical Imaging of Biocolloidal Self-Assemblies, Drug Delivery Systems, and Pulmonary Inhalation Aerosols. A Review. AAPS PharmSciTech (2007) 8 (4) November 30: Article 99:E1-E16. (Impact Factor: 1.445)[15]

8. Xu, Z., Mansour, H.M., Mulder, T., McLean, R., Langridge, J., and Hickey, A.J. Comparative Dispersion Study of Dry Powder Aerosols of Albuterol Sulfate/Lactose Monohydrate and Cromolyn Sodium/Lactose Monohydrate Delivered by Standardized Entrainment Tubes. Respiratory Drug Delivery (2008) 3: 897-900. [16]

9. Xu, Z., Mansour, H.M., Mulder, T., McLean, R., Langridge, J., and Hickey, A.J. Dry Powder Aerosols Generated by Standardized Entrainment Tubes from Drug Blends with Lactose Monohydrate: 1. Albuterol Sulfate and Disodium Cromoglycate. Journal of Pharmaceutical Sciences (2010) 99 (8) March 2: 3398-3414.(Impact Factor: 3.031)[17]

10. Xu, Z., Mansour, H.M., Mulder, T., McLean, R., Langridge, J., and Hickey, A.J. Dry Powder Aerosols Generated by Standardized Entrainment Tubes from Drug Blends with Lactose Monohydrate: 2. Ipratropium Bromide Monohydrate and Fluticasone Propionate. Journal of Pharmaceutical Sciences (2010) 99 (8) March 10: 3415-3429. (Impact Factor: 3.031)[18]

11. Mansour, H.M., Xu, Z., and Hickey, A.J. Dry Powder Aerosols Generated by Standardized Entrainment Tubes from Alternative Sugar Blends: 3. Trehalose Dihydrate and D-Mannitol Carriers. Journal of Pharmaceutical Sciences (2010) 99 (8) March12; 3430-3441.(Impact Factor: 3.031)[19]

12. Xu, Z., Mansour, H.M., Mulder, T., McLean, R., Langridge, J., and Hickey, A.J. Heterogenous Particle Deaggregation and Its Implications for Therapeutic Aerosol Performance. Journal of Pharmaceutical Sciences (2010) 99 (8) March 15: 3442-3461.(Impact Factor: 3.031)[20]

13. Xu, Z., Mansour, H.M., and Hickey, A.J. Particle Interactions in Dry Powder Inhaler Unit Processes. Journal of Adhesion Science and Technology: Special Issue on Adhesion Aspects in Pharmaceutical Sciences (2011): 25 (4/5) 451-482. (Impact Factor: 1.175)[21]

14. *Mansour, H.M.* It's Only Natural: Using Polymers in Drug Delivery. Pharmaceutical Technology (2009) 33 (1) January: 1-2. [22]

15. *Mansour, H.M.*, Rhee, Y.S., and Wu, X. Nanomedicine in Pulmonary Delivery. International Journal of Nanomedicine (2009) 4 December: 299-319.(Impact Factor: 4.976)[23]

16. *Mansour, H.M.*, Sohn, M., Al-Ghananeem, A., and DeLuca P.P. Materials for Pharmaceutical Dosage Forms: Molecular Pharmaceutics and Controlled Release Drug Delivery Aspects. Invited Paper. International Journal of Molecular Sciences: Special Issue-Material Sciences and Nanotechnology Section - Biodegradability of Materials in Biomedical Applications. (2010) 11: 3298-3322. (Impact Factor: 2.279)[24]

17. Rhee, Y.S., Park, C.W., DeLuca, P.P., and *Mansour, H.M.* Sustained-Release Injectable Drug Delivery Systems. An Invited Paper. Pharmaceutical Technology: Special Issue-Drug Delivery (2010) November: 6-13. [25]

18. Hayes, D. Jr., Zwischenberger, J.B., and Mansour, H.M. Aerosolized Tacrolimus: A Case Report in a Lung Transplant Recipient. Transplantation Proceedings (2010) 42 (9) November: 3876-3879. [26]

19. Wu, X., Li, X., and *Mansour, H.M.* Surface Analytical Techniques in Solid-State Particle Characterization: Implications for Predicting Performance in Dry Powder Inhalers. Invited Paper. KONA Powder and Particle Journal (2010) 28: 3-19. [27]

20. Rhee, Y.S. and *Mansour, H.M.* Nanopharmaceuticals I: Nanocarrier Systems in Drug Delivery. Invited Paper. International Journal of Nanotechnology: Special Issue-Nanopharmaceuticals. (2011) 8 (1/2): 84-114.[28]

21. Wu, X. and *Mansour, H.M.* Nanopharmaceuticals II: Application of Nanoparticles and Nanocarrier Systems in Pharmaceutics and Nanomedicine. Invited Paper. International Journal of Nanotechnology: Special Issue-Nanopharmaceuticals. (2011) 8 (1/2): 115-145. (Impact Factor: 1.329)[29]

22. Wu, X.,and *Mansour, H.M.* Pulmonary and Nasal Anti-Inflammatory and Anti-Allergy Inhalation Aerosol Delivery Systems. Invited Paper. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry: Special Issue-Optimizing a Therapeutic with Anti-Inflammatory Agents: Novel Drug Delivery Systems. (2011)10 (3): 215-229. [30]

23. Park, C.W., Hayes, D. Jr., and *Mansour, H.M.* Pulmonary Inhalation Aerosols for Targeted Antibiotics Drug Delivery. Invited Paper & Cover Page. European Pharmaceutical Review. (2011) 16 (1): 32-36.[31]

24. *Mansour, H.M.* Molecular Forces and Self Assembly in Colloid, Nano Sciences and Biology. Invited Paper. Journal of the American Chemical Society. (2011) 133 (13): 5162. (Impact Factor: 9.019) [32]

25. Hayes, D. Jr and Mansour, H.M. Improved Outcomes of Patients with End-Stage Cystic Fibrosis Requiring Invasive Mechanical Ventilation for Acute Respiratory Failure. Lung. (2011) 189 (5): 409-415. (Impact Factor: 1.734)[33] [34]

26. Park, C.W., Rhee, Y.S., Vogt, F.G., Hayes, D Jr., Zwischenberger, J.B., DeLuca, P.P., and *Mansour, H.M.* Advances in Microscopy and Complementary Imaging Techniques to Assess the Fate of Drugs Ex-Vivo in Respiratory Drug Delivery. Invited Paper. Advanced Drug Delivery Reviews: Special Theme Issue-Computational and Visualization Approaches in Respiratory Delivery. (2011). (Impact Factor: 13.577)[35]

27. Rhee, Y.S., Sohn, M., Woo, B.H., Thanoo, B.C., DeLuca, P.P., and *Mansour, H.M.* Sustained-Release Delivery of Octreotide from Biodegradable Polymeric Microspheres. AAPS PharmSciTech: Special Theme Issue-Sterile Products: Advances and Challenges in Formulation, Manufacturing, Devices and Regulatory Aspects.(2011)12 (4):1293-1301. (Impact Factor: 1.445)[36] [37]

28. Hayes, D. Jr., Winkler, M.A., Kirkby, S., Capasso, P., Mansour, H.M. and Attili, A.K. Preprocedural Planning with Prospectively Triggered Multi-Detector Row CT Angiography prior to Bronchial Artery Embolization in Cystic Fibrosis Patients with Massive Hemoptysis. Lung (2011).(Impact Factor: 1.734)[38]

29. DeLuca, P.P. and *Mansour, H.M.* Insight Interview: Drug Delivery & Formulation-Controlled Release . World Pharmaceutical Frontiers (2011)2(September): 61-64.[39]

30. Li, X. and *Mansour, H.M.* Physicochemical Characterization and Water Vapor Absorption of Organic Solution Advanced Spray Dried Trehalose Microparticles and Nanoparticles for Targeted Dry Powder Pulmonary Inhalation Delivery. AAPS PharmSciTech: Special Theme Issue: Advances in Pharmaceutical Excipients Research and Use: Novel Materials, Functionalities and Testing (2011)12(4):1420-1430. (Impact Factor: 1.445)[40] [41]

31. Hayes, D. Jr., Ball, A.M., Mansour, H.M., Martin, C.A.,and Flynn, J.D. Fungal Infection in Heart-Lung Transplant Recipients Receiving Single-agent Prophylaxis With Itraconazole. Experimental and Clinical Transplantation (2011)9 (6): 399-404. [42].

32. Willis, M.L., Hayes, D Jr., and *Mansour, H.M.* Therapeutic Liposomal Dry Powder Inhalation Aerosols for Targeted Lung Delivery. Lung (2012).(Impact Factor: 1.734)[43] [44]

33. Duan, J.H., Mansour, H.M., Zhang, Y.D., Deng, X.M., Zhao, J.F. Reversion of Multi-Drug Resistance by Co-Encapsulation of Doxorubicin and Curcumin in Chitosan/poly(butylcyanoacrylate) Nanoparticles. International Journal of Pharmaceutics(2012)(Impact Factor: 3.607)[45]

34. Hayes, D. Jr. and Mansour, H.M. Vanishing Bronchus Intermedius Syndrome in a Pediatric Patient with Cystic Fibrosis After Lung Transplantation. Pediatric Transplantation: The Official Journal of the International Pediatric Transplant Association (2012) [Impact Factor: 1.873](IN PRESS)[46]

Book Chapters *Corresponding Author*

1. Hickey, A.J. and Mansour, H.M. Book Volume 2, Book Chapter 43: Formulation Challenges of Powders for the Delivery of Small Molecular Weight Molecules as Aerosols. Modified-Release Drug Delivery Technology, Drugs and the Pharmaceutical Sciences Series, Rathbone, M. J., Hadgraft, J., Roberts, M.S., Lane, M.E, (Editors), Second Edition, Informa Healthcare, New York, (2008) pp. 573-602. [47]

2. Hickey, A.J. and Mansour, H.M. Book Volume 2, Chapter 5: Delivery of Drugs by the Pulmonary Route. Modern Pharmaceutics Volume 2: Applications and Advances, Drugs and the Pharmaceutical Sciences Series, Florence, A.T., Siepmann, J. (Editors), Fifth Edition, Taylor & Francis, Inc., New York, (2009): 191-219. [48]

3. *Mansour, H.M.*, Rhee, Y.S., Park, C.W., and DeLuca, P.P. Book Chapter 9: Lipid Nanoparticulate Drug Delivery and Nanomedicine. Lipids in Nanotechnology. 302 pages. Moghis, A. (Editor), First Edition, American Oil Chemists Society (AOCS) Press, Urbana, Illinois (2011) pp.221-268. [49]

4. *Mansour, H.M.*, Park, C.W., and Bawa, R. Book Volume 1, Chapter: Design and Development of Approved Nanopharmaceutical Products. Clinical Nanomedicine: from Bench to Bedside. Series of Nanomedicine Pan Stanford Publishing/CRC Press, Inc., London, United Kingdom (2011) pp. 1-27.

5. *Mansour, H.M.* and Park, C.W. Book Chapter: Therapeutic and Clinical Aspects of Nanomedicines and Nanopharmaceutical Products. The Nanomedicine Handbook for Clinicians. CRC Press, Inc., London, United Kingdom (2011).

6.*Mansour, H.M.*, Park, C.W., and Hayes, D. Jr. Book Chapter: Nanoparticle Lung Delivery and Inhalation Aerosols for Targeted Pulmonary Nanomedicine. Nanomedicine in Drug Delivery. CRC Press/Taylor Francis, Inc., London, United Kingdom (2011). [50]

7.*Mansour, H.M.*, Park, C.W., Rhee, Y.S., and DeLuca, P.P. Book Chapter: Novel Drug Delivery Systems. Drug Delivery. Mitra, A.K. (Editor), First Edition, Jones & Bartlett, Burlington, MA. (2012)

Edited Book (co-Editor)

1. Nanomedicine in Drug Delivery, Kumar, A., Mansour, H.M., Friedman, A., and Blough, E. (Editors), First Edition, CRC Press/Taylor & Francis, London, United Kingdom. 450 pages. [51]

Professional Memberships

• Academy of Pharmaceutical Sciences of Great Britain
• American Association for Aerosol Research
• American Association of Colleges of Pharmacy
• American Association of Pharmaceutical Scientists
• American Chemical Society
• American Pharmacists Association
• American Society of Nanomedicine
• Controlled Release Society
• European Federation for Pharmaceutical Sciences
• European Cystic Fibrosis Society
• Golden Key
• International Association of Colloid and Interface Scientists
• International Liposome Society
• International Microencapsulation Society
• International Pharmaceutical Federation
• International Society for Aerosols in Medicine
• Phi Eta Sigma
• Phi Kappa Phi
• Rho Chi
• United States Pharmacopeia (USP)-UK COP Delegate

Research Lab Group Members **Postdoctoral Research Visiting Scholar Positions Available**

1. Dr. Yun-Seok Rhee, Ph.D., Postdoctoral Research Scholar

2. Dr. Xiao Wu, Ph.D., Postdoctoral Research Scholar

3. Dr. Chun-Woong Park, Ph.D., Postdoctoral Research Scholar

4. Dr. Jinghua Duan, Ph.D., Postdoctoral Research Scholar

5. Dr. Samantha Meenach, NIH NCI CNTC Postdoctoral Fellow

6. Dr. Wei Fen Zhang, Visiting Professor

7. MinJi Sohn, M.S., Visiting Graduate Student Research Scholar

8. Xiaojian Li, M.S., Doctoral Candidate (Dissertator) & Center of Membrane Sciences Fellow

9. Lauren Willis, Pharm.D. Student Researcher

10. Amber Jerke, NSF-REU Research Fellow

11. Charles Ritchie, HPLC Research Technician

12.Wei Qui, Animal Research Technician

13. Dr. Helieh Oz, Research Associate Professor

Co-Advisor Lab Group Members

1. Nathanael Stocke, NSF-IGERT Fellow, College of Engineering

2. Alexander McKinlay, NSF-REU Fellow, Department of Biomedical Engineering

Meeting Abstracts selected from 2006-Present (over 30 abstracts prior to 2006)*Presenting Author*

1.*Mansour, H.M.*, Damodaran, S., and Zografi, G. Surface Structural Characterization and Effects of a Surface-Active, Hydrophobic Heteropolypeptide, KL4, on Phospholipid Bilayer Spreading and Monolayer Phase Behavior at the Air-Water Interface: Implications for Pulmonary Surfactant Delivery. The 10th Annual Liposome Research Days & The 1st Univ. of North Carolina Drug Conference, Chapel Hill, NC, 2006.

2.*Mansour, H.M.*, Kujanpää, J., Tuomenoja, H., Papadopoulos, D., Mulder, T., Langridge, J., and Hickey, A.J. Characterization of the Effects of Various Sugar Carriers and Inhalation Devices on the Surface Electrostatics of Aerosolized Dry Powder Inhalation Particles containing Albuterol Sulfate. The AAPS Journal (2006) 8 (S2) M1239.

3.*Mansour, H.M.*, Kujanpää, J., Tuomenoja, H., and Hickey, A.J. Electrostatic Charge Behavior of Aerosolized Pharmaceutical Particles for Various Drug/Sugar Carrier Dry Powder Inhalation Particulate Systems. The AAPS Journal (2006) 8 (S2) M1245.

4.*Mansour, H.M.*, Xu, Z., and Hickey, A.J. Characterization of Dry Powder Aerosols of Albuterol Sulfate and Cromolyn Sodium with Various Sugar Carriers Delivered by Standardized Entrainment Tubes. The AAPS Journal (2007) 9 (S2) W5234.

5.Xu, Z., Mansour, H.M., Mulder, T., McLean, R., Langridge, J., and Hickey, A.J. Characterization of Dry Powder Aerosols of Albuterol Sulfate/Lactose Monohydrate and Cromolyn Sodium/Lactose Monohydrate Delivered by Standardized Entrainment Tubes. The AAPS Journal (2007) 9 (S2) W5235.

6.Xu, Z., Mansour, H.M., Mulder, T., McLean, R., Langridge, J., and Hickey, A.J. Performance Evaluation of Dry Powder Aerosol Formulation Using Modified Surface Adsorption Expression. The AAPS Journal (2009) (S2) R6197.

7.Xu, Z., Mansour, H.M., Mulder, T., McLean, R., Langridge, J., and Hickey, A.J. Heterogenous Particle Deaggregation and Its Implication for Therapeutic Aerosol Performance. The AAPS Journal (2009) (S2) R6198.

8.Mansour, H.M., Sohn, M., Rhee, Y.S., Woo, B., and DeLuca P.P. Sustained Release Delivery of Octreotide Acetate from Biodegradeable Polymeric Microspheres. The AAPS Journal (2009) (S2) W5036.

9.Jerke, A., Dziubla, T.D., and Mansour, H.M. Physical and Chemical Characterization of Various Pulmonary Drugs and Sugars for Targeted Pulmonary Delivery. NSF-REU Summer Research Symposium, University of Kentucky College of Engineering, Lexington, KY (July 2009)

10.Ma, J., Dziubla, T.D., and Mansour, H.M. Advanced Spray Dried Particles for Targeted Pulmonary Delivery in Lung Cancer. NSF-IGERT Spring Research Symposium, University of Kentucky College of Engineering, Lexington, KY (May 2010)

11.Li, X. and Mansour, H.M. Physicochemical Characterization and Water Vapor Sorption of Advanced Spray Dried Trehalose Microparticles and Nanoparticles in the Solid-State for Targeted Pulmonary Delivery as Dry Powders. Pharmaceutics Graduate Student Research Meeting (PGSRM). The Ohio State University College of Pharmacy, Columbus, OH. (June 2010).

12.Ma, J., Dziubla, T.D., and Mansour, H.M. Advanced Spray Dried Particles for Targeted Pulmonary Delivery in Lung Cancer. Pharmaceutics Graduate Student Research Meeting (PGSRM). The Ohio State University College of Pharmacy, Columbus, OH. (June 2010).

13.Wu, X. and Mansour, H.M. Advanced Spray Dried Tacrolimus Particles for Lung Transplant Immunosuppression By Targeted Dry Powder Pulmonary Inhalation Delivery. Pharmaceutics Graduate Student Research Meeting (PGSRM). The Ohio State University College of Pharmacy, Columbus, OH. (June 2010).

14.Williamson, J. and Mansour, H.M. Advanced Co-Spray Dried Disodium Cromoglycate and Fluticasone Propionate Microparticles and Nanoparticles for Combination Drug Pulmonary Inhalation Delivery. UK COP SURP Research Symposium, Lexington, KY (July 2010).

15.Li, X. and Mansour, H.M. Physicochemical Characterization and Water Vapor Sorption of Advanced Spray Dried Trehalose Microparticles and Nanoparticles in the Solid-State for Targeted Pulmonary Delivery as Dry Powders. UK COP Research Symposium on Drug Discovery & Development, Lexington, KY (October 2010).

16.Li, X., Hayes, D. Jr., and Mansour, H.M. Comparison of Advanced Spray Dried Micro/Nanoparticulate Aerosols of Antibiotics, Tobramycin and Azithromycin, in the Solid-State for Cystic Fibrosis Treatment: I. Manufacture and Characterization. UK COP Research Symposium on Drug Discovery & Development, Lexington, KY (October 2010).

17.Ma, J., Dziubla, T.D., and Mansour, H.M. Advanced Spray Dried Particles for Targeted Pulmonary Delivery in Lung Cancer. UK COP Research Symposium on Drug Discovery & Development, Lexington, KY (October 2010).

18.Ma, J., Carlson, S., Saatman, K.E., and Mansour, H.M. Advanced Spray Dried PLGA Particles for Subcutaneous Delivery. UK COP Research Symposium on Drug Discovery & Development, Lexington, KY (October 2010).

19.Park, C.W, Hayes, D. Jr., and Mansour, H.M. Advanced Spray-Dried Vancomycin Hydrochloride and Clarithromycin Particles for Targeted Pulmonary Inhalation Delivery as Dry Powders. UK COP Research Symposium on Drug Discovery & Development, Lexington, KY (October 2010).

20.Park, C.W, Hayes, D. Jr., and Mansour, H.M. Advanced Spray-Dried Vancomycin Hydrochloride and Clarithromycin Lipospheres for Targeted Pulmonary Inhalation Delivery. UK COP Research Symposium on Drug Discovery & Development, Lexington, KY (October 2010).

21.Ma, J., Dziubla, T.D., and Mansour, H.M. Targeted Dry Powder Microparticulate/Nanoparticulate Pulmonary Delivery in Bronchoalveolar Carcinoma by Therapeutic-Mucolytic Particles. UK Markey Cancer Research Day 2011, Lexington, KY (March 2011).

22.Li, X. and *Mansour, H.M.* Quality-By-Design for Excipient Functionality: Advanced Spray-Dried Trehalose Microparticles and Nanoparticles for Targeted Pulmonary Inhalation Delivery. International Pharmaceutical Excipient Council (IPEC) Excipient Fest 2011, Baltimore, MD. (Mansour, H. M. Presenting Author).

23.Li, X., Hayes, D. Jr, and *Mansour, H.M.* Targeted Pulmonary Delivery by Multifunctional Microparticulate/Nanoparticulate Pharmaceutical Inhalation Aerosols for Cystic Fibrosis Combination Drug/Mucolytic Treatment. European Cystic Fibrosis Society (ECFS) Basic Science Conference 2011 Tirrenia-Pisa, Italy. (Mansour, H.M. Presenting Author)

24.Park, C.W, Hayes, D. Jr., and Mansour, H.M. Advanced Spray-dried Vancomycin hydrochloride and Clarithromycin Particles for Targeted Pulmonary Inhalation Delivery as Dry Powders. Controlled Release Society Annual Meeting & Exhibition 2011 National Harbor, MD.

25.Li, X., Hayes, D. Jr, and Mansour, H.M. Advanced Spray Dried Microparticles/Nanoparticles of Antibiotics and a Mucolytic in the Solid-state for Cystic Fibrosis Treatment by Targeted Pulmonary Delivery. Controlled Release Society Annual Meeting & Exhibition 2011 National Harbor, MD.

26.Ma, J., Dziubla, T.D., and Mansour, H.M. Advanced Spray Dried Particles for Targeted Pulmonary Delivery in Lung Cancer. Controlled Release Society Annual Meeting & Exhibition 2011 National Harbor, MD.

27.*Mansour, H.M.* Rational Design, Development, and Optimization of Nanopharmaceuticals for Targeted Drug Delivery in Nanomedicine-An Interfacial and Colloidal Science Approach. 242th American Chemical Society (ACS) 2011 Annual Meeting-ACS Colloid & Surfaces Symposium on Nanomedicine.

28.*Mansour, H.M.* Advanced Pulmonary Medicine by Targeted Pulmonary Inhalation Drug Delivery as Respirable Multifunctional Microparticles and Nanoparticles. 2011 Gordon Research Conference (GRC)-Lung Development, Injury & Repair, Rhode Island.

29.*Mansour, H.M.* Phospholipid Nanopharmaceuticals in Advanced Drug Delivery. 2011 American Oil Chemist's Society (AOCS) Annual Meeting & Exhibition, Symposium on “Phospholipids in Pharma and Cosmetics Applications", Cincinnati, OH. (Symposium Speaker).

30.Stocke, N., Mansour, H.M., and Hilt, J.Z. Enhanced Transport of PEG-Based Magnetic Nanocomposites In Artificial Mucus Barriers. 2011 American Institute of Chemical Engineers (AIChE) Annual Meeting & Exhibition, "Nanoscale Science and Engineering Forum".

31. Li, X., Hayes, D. Jr, and Mansour, H.M. Advanced Spray-Dried Microparticulate/Nanoparticulate Powders for Cystic Fibrosis Treatment by Targeted Pulmonary Delivery. 2011 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting & Exhibition.

32. *Mansour, H.M.*, Park, C.W, Vogt, F.G., and Hayes, D. Jr. Advanced Spray-Dried Vancomycin Hydrochloride and Clarithromycin Lipospheres for Targeted Pulmonary Inhalation Aerosol Delivery. 4th Annual Nanotechnology & Nanomedicine Symposium.

33. McKinlay, A., Zou, Y., Millbrandt, T., Mansour, H.M., and Puleo, D.A. Encapsulation of Vancomycin and Ketoprofen in PLGA Microspheres for Treating Bacterial Infection and Inflammation in Joints. NSF-REU Summer Research Symposium, University of Kentucky College of Engineering, Lexington, KY.

34. McKinlay, A., Zou, Y., Millbrandt, T., Mansour, H.M., and Puleo, D.A. Encapsulation of Vancomycin and Ketoprofen for Treating Bacterial Infection and Inflammation in Joints. 2011 American Institute of Chemical Engineers (AIChE) Annual Meeting & Exhibition, "Nanoscale Science and Engineering Forum".

35. *Mansour, H.M.*, Li, X, and Hayes, D. Jr. TARGETED LUNG DELIVERY BY INHALABLE MULTIFUNCTIONAL MICROPARTICULATE/NANOPARTICULATE AEROSOLS FOR CYSTIC FIBROSIS COMBINATION DRUG/MUCOLYTIC TREATMENT. 2011 North American Cystic Fibrosis Foundation Conference (NACFC) .