David Lowry: Difference between revisions
No edit summary |
|||
(107 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
California State University, Monterey Bay: Assistant Professor 2014 | |||
The University of Texas at Austin: Postdoctoral Fellow, 2010- | The University of Texas at Austin: USDA NIFA Postdoctoral Fellow, 2010-2013 | ||
Duke University: PhD, | Duke University: PhD, 2004-2010 | ||
The University of California, Berkeley: BS, | The University of California, Berkeley: BS, 1997-2001 | ||
==Research Interests== | ==Research Interests== | ||
[[Image:Perdenales.jpg|thumb|left|Switchgrass in its native riparian habitat in central Texas]] | |||
[[Image: | [[Image:Lowry_field_2.JPG|thumb|right|Field experiment with ''Mimulus guttatus'']] | ||
'''The genetics of adaptation and speciation''' | '''The genetics of adaptation and speciation''' | ||
Adaptation is the most fundamental way that the environment can | Adaptation is the most fundamental way that the environment can change the phenotypes of organisms. Adaptations can also lead to the formation of reproductive isolating barriers, which are the building blocks of new species. I am very interested in understanding the genetic underpinnings of reproductive isolation at various stages in the speciation process. | ||
Understanding adaptation is also crucial to predicting how organisms will respond to future global change and will help inform management decisions as well as guide future agricultural breeding. | Understanding adaptation is also crucial to predicting how organisms will respond to future global change and will help inform management decisions as well as guide future agricultural breeding. | ||
Line 21: | Line 20: | ||
'''Landscape evolutionary genomics''' | '''Landscape evolutionary genomics''' | ||
One of the core goals of my research program is to understand how the natural landscape molds the genomes of organisms through adaptation. To that end, I am using a combination of genetic mapping and genome sequencing approaches to identify genes involved with adaptation to the heterogeneity of the natural landscape. During my dissertation, I focused on how adaptive alleles in ''Mimulus guttatus'' are spread across the landscape and what phenotypic effects they have in different environments across western North America. Currently, I am developing ''Panicum'' grasses as a model system to understand adaptation along a longitudinal soil moisture cline across | One of the core goals of my research program is to understand how the natural landscape molds the genomes of organisms through adaptation. To that end, I am using a combination of genetic mapping and genome sequencing approaches to identify genes involved with adaptation to the heterogeneity of the natural landscape. During my dissertation, I focused on how adaptive alleles in ''Mimulus guttatus'' are spread across the landscape and what phenotypic effects they have in different environments across western North America. Currently, I am developing ''Panicum'' grasses as a model system to understand adaptation along a longitudinal soil moisture cline across Southwestern United States and a latitudinal temperature cline across the Great Plains. Our lab recently [http://www.utexas.edu/news/2012/08/02/biologist-grant-study-potential-biofuel-crops/ received funding from the Department of Energy] to develop ''Panicum hallii'' as a model system for local adaptation and bioenergy research. | ||
'' | |||
[[Image:Diversity.JPG|thumb|left|Phenotypic diversity of Switchgrass, ''Panicum virgatum'']] | |||
[[Image:Field_2012.JPG|thumb|right|Field experiment with ''Panicum hallii'']] | |||
'''Using evolutionary biology to improve bioenergy crops''' | '''Using evolutionary biology to improve bioenergy crops''' | ||
Civilization is built on a foundation of domesticated grasses. Without those grasses (corn, wheat, rice, oats, barley, sorghum) there would be no ballet and human beings would never of landed on the moon. Plant breeders have quietly worked in the shadows to increase the yield of crops and in turn maintain our modern world. | Civilization is built on a foundation of domesticated grasses. Without those grasses (corn, wheat, rice, oats, barley, sorghum) there would be no ballet and human beings would never of landed on the moon. Plant breeders have quietly worked in the shadows to increase the yield of crops and in turn maintain our modern world. | ||
Now, there may actually be potential to domesticate a new set of grass species to use to help combat the growing energy problem. My research is focused understanding the factors involved in local adaptation in the bioenergy crop switchgrass (''Panicum virgatum''). Loci involved in local adaptation are likely to be of high value to crop breeders interested in improving drought, heat, cold, herbivore, and disease tolerance. | Now, there may actually be potential to domesticate a new set of grass species to use to help combat the growing energy problem. My research is focused understanding the factors involved in local adaptation in the bioenergy crop switchgrass (''Panicum virgatum''). Loci involved in local adaptation are likely to be of high value to crop breeders interested in improving drought, heat, cold, herbivore, and disease tolerance. | ||
Line 36: | Line 33: | ||
==Publications== | ==Publications== | ||
[[Image: | [[Image:PLoS.jpg|thumb|left|Cover photo for PLoS Biology]] | ||
'''Lowry D. B.''', R. Hopkins. ( | [[Image:PhilTransCover.jpg|thumb|right|]] | ||
'''PDFs for publications available through my''' [http://davidbryantlowry.wordpress.com/publications/ '''website'''] | |||
'''Lowry, D. B.''', K. Hernandez, S. H. Taylor, E. Meyer, T. L. Logan, J. A. Chapman, D. S. Rokhsar, J. Schmutz, T. E. Juenger. The genetics of divergence and reproductive isolation between ecotypes of ''Panicum hallii''. ''In revision'' | |||
Oneal, E., '''D. B. Lowry''', K. M. Wright, Z. Zhu, J. H. Willis. Divergent population structure and climate associations of a chromosomal inversion polymorphism across the ''Mimulus guttatus'' species complex. ''In revision'' | |||
Aspinwall, M. J., S. H. Taylor, '''D. B. Lowry''', P. A. Fay, A. Khasanova, J. Bonnette, B. K. Whitaker, N. S. Johnson, C. V. Hawkes, T. E. Juenger. Physiological plasticity among differentially adapted genotypes of a widespread C4 grass under altered precipitation. ''In review'' | |||
Lasky, J. R., D. L. Des Marais, '''D. B. Lowry''', I. Povolotskaya, J. K. McKay, J. H. Richards, T. H. Keitt, T. E. Juenger. Natural variation in abiotic stress responsive gene expression is associated with local adaptation to climate in ''Arabidopsis thaliana.'' ''In revsion'' | |||
Meyer, E., M. J. Aspinwall, '''D. B. Lowry''', J. Palacio-Mejía, T. L. Logan, P. A. Fay, T. E. Juenger. (2014) Integrating physiological, transcriptional, and metabolomic responses to drought stress and recovery in switchgrass (''Panicum virgatum'' L.). BMC Genomics. ''In press'' | |||
[http://www.amnat.org/an/newpapers/VPLowry.html '''Lowry, D. B.''', K. D. Behrman, P. Grabowski, G. P. Morris, J. R. Kiniry, T. E. Juenger. (2014) Adaptation between ecotypes and along environmental gradients in ''Panicum virgatum.'' The American Naturalist ''In press''] | |||
[http://www.plantcell.org/content/early/2013/09/16/tpc.113.115352.short?keytype=ref&ijkey=6c6d7ZU4jKR8aPZ '''Lowry, D. B.''', T. L. Logan, L. Santuari, C. S. Hardtke, J. H. Richards, L. J. DeRose-Wilson, J. K. McKay, S. Sen, T. E. Juenger. (2013) Expression QTL mapping across water availability environments reveals contrasting associations with genomic features in ''Arabidopsis thaliana''. The Plant Cell 25: 3266–3279.] | |||
[http://press.princeton.edu/titles/10100.html '''Lowry, D. B.''', R. Hopkins. (2013) “Speciation and Natural Selection.” In J. Losos (ed.). The Princeton Guide to Evolution. Pp. 512-519. Princeton University Press, Princeton, NJ, USA.] | |||
[http://onlinelibrary.wiley.com/doi/10.1111/nph.12341/abstract Aspinwall, M. J., '''D. B. Lowry''', S. H. Taylor, T. E. Juenger, C. V. Hawkes, M. V. Johnson, J. R. Kiniry, P. A. Fay. (2013) Genotypic variation in traits linked to climate and aboveground productivity in a widespread C4 grass: evidence for a functional trait syndrome. New Phytologist 199: 966-980.] | |||
[http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1001497 Wright, K. M., D. Lloyd, '''D. B. Lowry''', M. R. Macnair, J. H. Willis. (2013) Indirect evolution of hybrid lethality due to linkage with a selected locus in ''Mimulus guttatus.'' PLoS Biology 11: e1001497] | |||
[http://www.amjbot.org/content/early/2013/02/19/ajb.1200379.abstract '''Lowry, D. B.''', C. T. Purmal, T. E. Juenger. (2013) A population genetic transect of ''Panicum hallii'' (Poaceae). American Journal of Botany. 100:592-601] | |||
[http://onlinelibrary.wiley.com/doi/10.1111/j.1469-8137.2012.04146.x/full '''Lowry D. B.''' (2012) Local adaptation in The model plant. New Phytologist. 194: 888-890.] | [http://onlinelibrary.wiley.com/doi/10.1111/j.1469-8137.2012.04146.x/full '''Lowry D. B.''' (2012) Local adaptation in The model plant. New Phytologist. 194: 888-890.] | ||
[http://onlinelibrary.wiley.com/doi/10.1111/j.1095-8312.2012.01867.x/full '''Lowry D. B.''' (2012) Ecotypes and the controversy over stages in the formation of new species. Biological Journal of the Linnean Society. 106: 241-257.] | [http://onlinelibrary.wiley.com/doi/10.1111/j.1095-8312.2012.01867.x/full '''Lowry, D. B.''' (2012) Ecotypes and the controversy over stages in the formation of new species. Biological Journal of the Linnean Society. 106: 241-257.] | ||
[http://www.amjbot.org/content/99/3/e114.long '''Lowry, D. B.''', C. T. Purmal, E. Meyer, T. E. Juenger. (2012) Microsatellite markers for the native Texas perennial grass, ''Panicum hallii'' (Poaceae). American Journal of Botany Primer Notes & Protocols. 99: e114-e116] | [http://www.amjbot.org/content/99/3/e114.long '''Lowry, D. B.''', C. T. Purmal, E. Meyer, T. E. Juenger. (2012) Microsatellite markers for the native Texas perennial grass, ''Panicum hallii'' (Poaceae). American Journal of Botany Primer Notes & Protocols. 99: e114-e116] | ||
Line 48: | Line 69: | ||
[http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0030730 '''Lowry, D. B.''', C. S. Sheng, Z. Zhu, T. E. Juenger, B. Lahner, D. E. Salt, J. H. Willis. (2012) Mapping of ionomic traits in ''Mimulus guttatus'' reveals Mo and Cd QTLs that colocalize with MOT1 homologues. PLoS One 7: e30730.] | [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0030730 '''Lowry, D. B.''', C. S. Sheng, Z. Zhu, T. E. Juenger, B. Lahner, D. E. Salt, J. H. Willis. (2012) Mapping of ionomic traits in ''Mimulus guttatus'' reveals Mo and Cd QTLs that colocalize with MOT1 homologues. PLoS One 7: e30730.] | ||
[http://www.amjbot.org/content/early/2011/12/20/ajb.1100285.abstract '''Lowry D. B.''', C. S. Sheng,, J. R. Lasky, J.H. Willis. (2012) Five anthocyanin polymorphisms are associated with an R2R3-MYB cluster in ''Mimulus guttatus''. American Journal of Botany 99:82-91] | [http://www.amjbot.org/content/early/2011/12/20/ajb.1100285.abstract '''Lowry, D. B.''', C. S. Sheng,, J. R. Lasky, J.H. Willis. (2012) Five anthocyanin polymorphisms are associated with an R2R3-MYB cluster in ''Mimulus guttatus''. American Journal of Botany 99:82-91] | ||
[http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1000500 '''Lowry, D.B.,''' J. H. Willis. (2010) A widespread chromosomal inversion polymorphism contributes to a major life-history transition, local adaptation, and reproductive isolation. PLoS Biology 8: e1000500] | [http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1000500 '''Lowry, D.B.,''' J. H. Willis. (2010) A widespread chromosomal inversion polymorphism contributes to a major life-history transition, local adaptation, and reproductive isolation. PLoS Biology 8: e1000500] | ||
[http://www3.interscience.wiley.com/journal/123501089/abstract Hall M. C., '''D. B. Lowry''', J. H. Willis. (2010). | [http://www3.interscience.wiley.com/journal/123501089/abstract Hall, M. C., '''D. B. Lowry''', J. H. Willis. (2010). Is local adaptation in ''Mimulus guttatus'' caused by trade-offs at individual loci? Molecular Ecology. 19: 2739-2753] | ||
[http://rsbl.royalsocietypublishing.org/content/early/2010/01/22/rsbl.2009.0969.full '''Lowry, D. B.''' (2010) Landscape evolutionary genomics. Biology Letters. 6: 502-504] | [http://rsbl.royalsocietypublishing.org/content/early/2010/01/22/rsbl.2009.0969.full '''Lowry, D. B.''' (2010) Landscape evolutionary genomics. Biology Letters. 6: 502-504] | ||
[[Image:Evolution_cover.jpg|thumb|right|]] | |||
[http://www.springerlink.com/content/vm4456721023284g/ Wu, C. A., '''D. B. Lowry''', L. I. Nutter, J. H. Willis. (2010) Natural variation for drought response in the ''Mimulus guttatus'' species complex. Oecologia 162: 23-33] | [http://www.springerlink.com/content/vm4456721023284g/ Wu, C. A., '''D. B. Lowry''', L. I. Nutter, J. H. Willis. (2010) Natural variation for drought response in the ''Mimulus guttatus'' species complex. Oecologia 162: 23-33] | ||
Line 67: | Line 90: | ||
==Important Things== | ==Important Things== | ||
*[http://davidbryantlowry.wordpress.com/ My website] | |||
*[http://davidbryantlowry.wordpress.com/cv/ David Lowry CV] | |||
*[http://scholar.google.com/citations?view_op=list_works&hl=en&user=yp5xdBEAAAAJ&gmla=AJsN-F6DFaPZ9A0TNBwOFnsWZf9Y9S7rGntDIzs1ZOqg52GhHzGJ090M-xxUubHEHF3dyXE6XlN-jmJ1uYNJiAULSHsEkKAaqniu606ZwKxaDjIwB3wfiIkspwU-gntSRaYs7bNl5Mmy Google Scholar Citations ] | |||
*[https://github.com/davidbryantlowry Programming Scripts on Github] | |||
*'''Contact Info:''' You can contact me at davidbryantlowry@gmail.com. | *'''Contact Info:''' You can contact me at davidbryantlowry@gmail.com. | ||
*Make sure to check out the [[Mimulus Community]] and the [[Texas Switchgrass Collaborative]]. | *Make sure to check out the [[Mimulus Community]] and the [[Texas Switchgrass Collaborative]]. |
Revision as of 09:44, 15 April 2014
California State University, Monterey Bay: Assistant Professor 2014
The University of Texas at Austin: USDA NIFA Postdoctoral Fellow, 2010-2013
Duke University: PhD, 2004-2010
The University of California, Berkeley: BS, 1997-2001
Research Interests
The genetics of adaptation and speciation
Adaptation is the most fundamental way that the environment can change the phenotypes of organisms. Adaptations can also lead to the formation of reproductive isolating barriers, which are the building blocks of new species. I am very interested in understanding the genetic underpinnings of reproductive isolation at various stages in the speciation process.
Understanding adaptation is also crucial to predicting how organisms will respond to future global change and will help inform management decisions as well as guide future agricultural breeding.
Landscape evolutionary genomics
One of the core goals of my research program is to understand how the natural landscape molds the genomes of organisms through adaptation. To that end, I am using a combination of genetic mapping and genome sequencing approaches to identify genes involved with adaptation to the heterogeneity of the natural landscape. During my dissertation, I focused on how adaptive alleles in Mimulus guttatus are spread across the landscape and what phenotypic effects they have in different environments across western North America. Currently, I am developing Panicum grasses as a model system to understand adaptation along a longitudinal soil moisture cline across Southwestern United States and a latitudinal temperature cline across the Great Plains. Our lab recently received funding from the Department of Energy to develop Panicum hallii as a model system for local adaptation and bioenergy research.
Using evolutionary biology to improve bioenergy crops
Civilization is built on a foundation of domesticated grasses. Without those grasses (corn, wheat, rice, oats, barley, sorghum) there would be no ballet and human beings would never of landed on the moon. Plant breeders have quietly worked in the shadows to increase the yield of crops and in turn maintain our modern world.
Now, there may actually be potential to domesticate a new set of grass species to use to help combat the growing energy problem. My research is focused understanding the factors involved in local adaptation in the bioenergy crop switchgrass (Panicum virgatum). Loci involved in local adaptation are likely to be of high value to crop breeders interested in improving drought, heat, cold, herbivore, and disease tolerance.
Publications
PDFs for publications available through my website
Lowry, D. B., K. Hernandez, S. H. Taylor, E. Meyer, T. L. Logan, J. A. Chapman, D. S. Rokhsar, J. Schmutz, T. E. Juenger. The genetics of divergence and reproductive isolation between ecotypes of Panicum hallii. In revision
Oneal, E., D. B. Lowry, K. M. Wright, Z. Zhu, J. H. Willis. Divergent population structure and climate associations of a chromosomal inversion polymorphism across the Mimulus guttatus species complex. In revision
Aspinwall, M. J., S. H. Taylor, D. B. Lowry, P. A. Fay, A. Khasanova, J. Bonnette, B. K. Whitaker, N. S. Johnson, C. V. Hawkes, T. E. Juenger. Physiological plasticity among differentially adapted genotypes of a widespread C4 grass under altered precipitation. In review
Lasky, J. R., D. L. Des Marais, D. B. Lowry, I. Povolotskaya, J. K. McKay, J. H. Richards, T. H. Keitt, T. E. Juenger. Natural variation in abiotic stress responsive gene expression is associated with local adaptation to climate in Arabidopsis thaliana. In revsion
Meyer, E., M. J. Aspinwall, D. B. Lowry, J. Palacio-Mejía, T. L. Logan, P. A. Fay, T. E. Juenger. (2014) Integrating physiological, transcriptional, and metabolomic responses to drought stress and recovery in switchgrass (Panicum virgatum L.). BMC Genomics. In press
Lowry D. B. (2012) Local adaptation in The model plant. New Phytologist. 194: 888-890.
Lowry, D. B. (2010) Landscape evolutionary genomics. Biology Letters. 6: 502-504
Important Things
- Contact Info: You can contact me at davidbryantlowry@gmail.com.
- Make sure to check out the Mimulus Community and the Texas Switchgrass Collaborative.